公开(公告)号：WO2022234054A1

公开(公告)日：2022-11-10

申请号：PCT/EP2022/062227

申请日：2022-05-05

Applicant: 4LIVING BIOTECH ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT PASTEUR DE LILLE ,  UNIVERSITE DE LILLE

Inventor： RATTENBACH, Revital ,  BISMUTH, Keren ,  BRETON, Jérome ,  TROTTEIN, François ,  SENCIO, Valentin

IPC: A61K31/395 ,  A61K31/4709 ,  A61K45/06 ,  A61P11/00 ,  A61P31/16 ,  A61K31/4353 ,  A61K31/4427 ,  A61K31/192 ,  A61K31/404 ,  A61K31/573 ,  A61P31/14

Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or hydrate thereof, for use in the treatment of a viral pulmonary disease or a chronic respiratory distress syndrome (CRDS) resulting from a viral pulmonary disease in a subject, said disease being different from COVID-19, wherein formula (I) is Z-R-A-R'-Y, including plerixafor.

公开(公告)号：WO2021224356A1

公开(公告)日：2021-11-11

申请号：PCT/EP2021/061919

申请日：2021-05-05

Applicant: 4LIVING BIOTECH ,  UNIVERSITE DE BORDEAUX ,  CENTRE HOSPITALIER DE BORDEAUX ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM ,  INSTITUT PASTEUR DE LILLE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITÉ DE LILLE

Inventor： BERGER, Patrick ,  DUPIN, Isabelle ,  PREVEL, Renaud ,  JAMES, Chloé ,  GIRODET, Pierre-Olivier ,  BISMUTH, Keren ,  RATTENBACH, Revital ,  BRETON, Jérôme ,  TROTTEIN, Francois ,  SENCIO, Valentin

IPC: A61K31/395 ,  A61P11/00

Abstract: The present invention relates novel composition to for use in a method of treating COVID-19, comprising administering to a patient a therapeutically effective amount of at least one antagonist or inhibitor of chemokine receptor CXCR4.