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    NITRATION OF AROMATIC COMPOUNDS
    1.
    发明申请
    NITRATION OF AROMATIC COMPOUNDS 审中-公开
    芳香化合物的硝化

    公开(公告)号：WO2016118450A1

    公开(公告)日：2016-07-28

    申请号：PCT/US2016/013795

    申请日：2016-01-18

    Applicant: ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA ,  JAGADISH, Bhumasamudram ,  MASH, Eugene

    Inventor： JAGADISH, Bhumasamudram ,  MASH, Eugene

    IPC: C07C201/02 ,  C07C205/37

    CPC classification number: C07C201/08 ,  C07B2200/05 ,  C07C201/16 ,  C07C205/37 ,  C07C205/06 ,  C07C205/12

    Abstract: The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an anhydride compound under conditions sufficient to produce a reactive intermediate. The aromatic compound to be nitrated is then added to this reactive intermediate to produce a nitroaromatic compound. The nitroaromatic compound can be substituted with one or more, typically, one to three, and often one or two nitrate (-NO 2 ) groups.

    Abstract translation: 本发明提供一种硝化芳族化合物而不需要固体催化剂和/或任何有机溶剂和/或任何其它添加剂的方法。 典型的方法包括在足以产生反应性中间体的条件下混合或混合硝酸和酸酐化合物。 然后将待硝化的芳族化合物加入到该反应性中间体中以产生硝基芳族化合物。 硝基芳族化合物可以被一个或多个，通常为1-3个，通常为一个或两个硝酸根（-NO 2）基团取代。

    SULFONATED TETRAFLUOROETHYLENE BASED IONOMER COATED CARBON FIBER
    2.
    发明申请
    SULFONATED TETRAFLUOROETHYLENE BASED IONOMER COATED CARBON FIBER 审中-公开
    磺化四氟乙烯基离心涂层碳纤维

    公开(公告)号：WO2016086211A1

    公开(公告)日：2016-06-02

    申请号：PCT/US2015/062814

    申请日：2015-11-26

    Applicant: ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA ,  HEIEN, Michael ,  VREELAND, Richard ,  LAUDE, Nicholas ,  ATCHERLEY, Christopher

    Inventor： HEIEN, Michael ,  VREELAND, Richard ,  LAUDE, Nicholas ,  ATCHERLEY, Christopher

    IPC: H01M4/04

    CPC classification number: G01N27/308 ,  A61B5/14503 ,  A61B5/40 ,  A61B5/4064 ,  A61B5/685 ,  C04B35/62844 ,  C04B35/62886 ,  C04B2235/5248 ,  C08L71/00

    Abstract: The present invention provides a carbon fiber that is coated with a composite material. The composite material coating comprises a sulfonated tetrafluoroethylene based ionomer. The present invention also provides a method for producing and using the same. Some aspects of the invention provide a carbon fiber comprising a substantially uniformly coated composite material. In some embodiments, the term "substantially uniformly coated" refers to having a variation of thickness of the coating of about 25% or less, typically about 20% or less, often about 15% or less, more often about 10% or less, and most often about 5% or less throughout at least about 90%, typically at least about 95% and most often at least 98% of the length of the coated carbon fiber.

    Abstract translation: 本发明提供涂覆有复合材料的碳纤维。 复合材料涂层包含磺化四氟乙烯基离聚物。 本发明还提供了制造和使用该方法。 本发明的一些方面提供了一种包含基本均匀涂布的复合材料的碳纤维。 在一些实施方案中，术语“基本上均匀地涂覆”是指涂层的厚度变化为约25％或更少，通常约20％或更少，通常约15％或更少，更经常约10％或更少， 并且最经常为包覆碳纤维长度的至少约90％，通常为约5％或更少，通常为至少约95％，最经常为至少98％。

    METHOD FOR TREATING COGNITIVE DYSFUNCTION
    7.
    发明申请
    METHOD FOR TREATING COGNITIVE DYSFUNCTION 审中-公开
    治疗认知功能障碍的方法

    公开(公告)号：WO2015002903A1

    公开(公告)日：2015-01-08

    申请号：PCT/US2014/044962

    申请日：2014-06-30

    Applicant: ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA ,  HAY, Meredith ,  BARNES, Carol ,  KONHILAS, John

    Inventor： HAY, Meredith ,  BARNES, Carol ,  KONHILAS, John

    IPC: A61K38/08

    CPC classification number: A61K38/085 ,  A61K9/0019 ,  A61K31/381

    Abstract: The present invention provides compositions and methods for treating cognitive impairment or dysfunction in a subject. In particular, the present invention provides a method for using a composition comprising an angiotensin-(l-7) receptor agonist to treat cognitive dysfunction or impairment that is due to a various clinical conditions including, but not limited to, those associated with increase in inflammation, cytokine production, increases in reactive oxygen species, changes in expression of brain inflammatory related genes and/or in the expression of genes involved in learning and memory within the central nervous system of a subject.

    Abstract translation: 本发明提供用于治疗受试者的认知障碍或功能障碍的组合物和方法。 特别地，本发明提供了一种使用包含血管紧张素（I-7）受体激动剂的组合物来治疗由于各种临床状况而引起的认知功能障碍或损伤的方法，包括但不限于与增加相关的那些 炎症，细胞因子产生，活性氧物质的增加，脑炎症相关基因的表达变化和/或涉及受试者中枢神经系统内的学习和记忆的基因的表达。

    AUTOMATED DETECTION METHOD FOR INSIDER THREAT
    10.
    发明申请
    AUTOMATED DETECTION METHOD FOR INSIDER THREAT 审中-公开
    内部威胁的自动检测方法

    公开(公告)号：WO2014205149A1

    公开(公告)日：2014-12-24

    申请号：PCT/US2014/043057

    申请日：2014-06-18

    Applicant: ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA ,  VALACICH, Joseph, S. ,  JENKINS, Jeffrey, L.

    Inventor： VALACICH, Joseph, S. ,  JENKINS, Jeffrey, L.

    IPC: G06F21/00

    CPC classification number: A61B5/164 ,  G06F21/316 ,  G06F21/32 ,  G06F21/40

    Abstract: The present invention provides a system and a method for eliciting information to sensitive questions and reliably detecting whether one is being deceptive, concealing information, or experiencing a heightened emotional response to the question. In particular, the system and the method of the invention are based on analyzing the user behavioral biometric of using one or more input device(s).

    Abstract translation: 本发明提供了一种用于向敏感问题引出信息并可靠地检测一个是欺骗性的，隐藏信息还是对该问题经历高度的情绪反应的系统和方法。 特别地，本发明的系统和方法基于分析使用一个或多个输入设备的用户行为生物特征。

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