公开(公告)号：WO2008047129A2

公开(公告)日：2008-04-24

申请号：PCT/GB2007/003978

申请日：2007-10-18

Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH ,  BAXTER, Robert, Laurence ,  JONES, Anita, Claire ,  BAXTER, Helen, Cochrane ,  RICHARDSON, Patricia, Rose ,  GRANT, Keith, James ,  HALOUANI, Hatem

Inventor： BAXTER, Robert, Laurence ,  JONES, Anita, Claire ,  BAXTER, Helen, Cochrane ,  RICHARDSON, Patricia, Rose ,  GRANT, Keith, James ,  HALOUANI, Hatem

IPC: G01N33/58 ,  C07D493/10

CPC classification number: C07D311/90 ,  C07D219/02 ,  C07D335/20 ,  G01N33/542

Abstract: Compounds for use as latent fluorescent probes, and methods for the detection of biological matter on surgical instruments, and for the detection of analytes, is described. The compounds comprise a fluorophore, and an associated fluorescence quencher which inhibits the normal fluorescence of the fluorophore until certain conditions are fulfilled, which conditions may include contact of the compound with a biological material including substances capable of reacting with one or more functionalities of the compound.

Abstract translation: 描述了用作潜在荧光探针的化合物，以及用于检测手术器械上的生物物质以及用于检测分析物的方法。 所述化合物包含荧光团和相关荧光猝灭剂，其抑制荧光团的正常荧光，直到满足特定条件，该条件可包括使化合物与生物材料接触，生物材料包括能够与化合物的一种或多种官能团反应的物质 。

公开(公告)号：WO2008047129A3

公开(公告)日：2008-11-27

申请号：PCT/GB2007003978

申请日：2007-10-18

Applicant: UNIV EDINBURGH ,  BAXTER ROBERT LAURENCE ,  JONES ANITA CLAIRE ,  BAXTER HELEN COCHRANE ,  RICHARDSON PATRICIA ROSE ,  GRANT KEITH JAMES ,  HALOUANI HATEM

Inventor： BAXTER ROBERT LAURENCE ,  JONES ANITA CLAIRE ,  BAXTER HELEN COCHRANE ,  RICHARDSON PATRICIA ROSE ,  GRANT KEITH JAMES ,  HALOUANI HATEM

IPC: G01N33/58 ,  C07D493/10

CPC classification number: C07D311/90 ,  C07D219/02 ,  C07D335/20 ,  G01N33/542

Abstract: Compounds for use as latent fluorescent probes, and methods for the detection of biological matter on surgical instruments, and for the detection of analytes, is described. The compounds comprise a fluorophore, and an associated fluorescence quencher which inhibits the normal fluorescence of the fluorophore until certain conditions are fulfilled, which conditions may include contact of the compound with a biological material including substances capable of reacting with one or more functionalities of the compound.

Abstract translation: 描述了用作潜在荧光探针的化合物，以及用于检测外科器械上的生物物质的方法和用于检测分析物的方法。 所述化合物包含荧光团和相关联的荧光猝灭剂，其抑制荧光团的正常荧光，直到满足某些条件，该条件可包括化合物与生物材料的接触，包括能够与化合物的一种或多种官能团反应的物质 。