公开(公告)号：WO2008115385A3

公开(公告)日：2009-01-08

申请号：PCT/US2008003292

申请日：2008-03-12

Applicant: SCHERING CORP ,  BLACK TODD A ,  MCNICHOLAS PAUL M ,  WALKER SCOTT S ,  XU YIMING ,  TING PAULINE C

Inventor： BLACK TODD A ,  MCNICHOLAS PAUL M ,  WALKER SCOTT S ,  XU YIMING ,  TING PAULINE C

IPC: A61K31/501 ,  A01N43/60 ,  A61P31/10

CPC classification number: A61K31/501 ,  A01N43/58 ,  A01N43/60

Abstract: There is disclosed a method for treating or preventing fungal infections comprising the administration of at least one glucan synthase inhibitor of a formula as described above in the specification or a pharmaceutically acceptable salt thereof; also claimed are methods of preparing pharmaceutical compositions comprising a compound as described above in the specification and a carrier, method of treating or preventing fungal infections comprising administration of combinations of glucan synthase inhibitor of a formula as described above in the specification and other antifungal agents, and method of treating or preventing fungal infections comprising administration of pharmaceutical compositions prepared according to a method described above in the specification, and a method of preparing a kit in a single package of the above described pharmaceutical composition and other antifungal agents.

Abstract translation: 公开了一种用于治疗或预防真菌感染的方法，其包括施用至少一种如说明书中所述的式的葡聚糖合成酶抑制剂或其药学上可接受的盐; 还要求的是制备药物组合物的方法，所述药物组合物包含上述说明书中所述的化合物和载体，治疗或预防真菌感染的方法，包括施用上述说明书中所述的式的葡聚糖合成酶抑制剂和其它抗真菌剂的组合， 以及治疗或预防真菌感染的方法，包括施用根据说明书中所述的方法制备的药物组合物，以及在上述药物组合物和其它抗真菌剂的单一包装中制备试剂盒的方法。

公开(公告)号：WO2008115385A2

公开(公告)日：2008-09-25

申请号：PCT/US2008/003292

申请日：2008-03-12

Applicant: SCHERING CORPORATION ,  BLACK, Todd, A. ,  MCNICHOLAS, Paul, M. ,  WALKER, Scott, S. ,  XU, Yiming ,  TING, Pauline, C.

Inventor： BLACK, Todd, A. ,  MCNICHOLAS, Paul, M. ,  WALKER, Scott, S. ,  XU, Yiming ,  TING, Pauline, C.

IPC: A61K31/501 ,  A61P31/10 ,  A01N43/60

CPC classification number: A61K31/501 ,  A01N43/58 ,  A01N43/60

Abstract: There is disclosed a method for treating or preventing fungal infections comprising the administration of at least one glucan synthase inhibitor of a formula as described above in the specification or a pharmaceutically acceptable salt thereof; also claimed are methods of preparing pharmaceutical compositions comprising a compound as described above in the specification and a carrier, method of treating or preventing fungal infections comprising administration of combinations of glucan synthase inhibitor of a formula as described above in the specification and other antifungal agents, and method of treating or preventing fungal infections comprising administration of pharmaceutical compositions prepared according to a method described above in the specification, and a method of preparing a kit in a single package of the above described pharmaceutical composition and other antifungal agents.

Abstract translation: 公开了一种用于治疗或预防真菌感染的方法，其包括施用至少一种如说明书中所述的式的葡聚糖合成酶抑制剂或其药学上可接受的盐; 还要求的是制备药物组合物的方法，所述药物组合物包含上述说明书中所述的化合物和载体，治疗或预防真菌感染的方法，包括施用上述说明书中所述的式的葡聚糖合成酶抑制剂和其它抗真菌剂的组合， 以及治疗或预防真菌感染的方法，包括施用根据说明书中所述的方法制备的药物组合物，以及在上述药物组合物和其它抗真菌剂的单一包装中制备试剂盒的方法。