公开(公告)号：WO1988004552A1

公开(公告)日：1988-06-30

申请号：PCT/HU1987000058

申请日：1987-12-18

Applicant: CHINOIN GYOGYSZER ÉS VEGYÉSZETI TERMÉKEK GYARA ... ,  BODO, György ,  KNOLL József ,  SOMFAI, Éva ,  VIRAG, Sándor ,  ZAK, Ferenc

Inventor： CHINOIN GYOGYSZER ÉS VEGYÉSZETI TERMÉKEK GYARA ...

IPC: A61K31/135

CPC classification number: A61K31/135

Abstract: The compounds of general Formula I (wherein R is hydrogen or halogen) and pharmaceutically acceptable acid addition salts thereof are suitable for the prophylaxis of undesired and unfavourable symptoms (e.g. perspiration, nausea, vomiting, dizziness, etc.)which occur when healthy humans or mammal animals are subjected to unusual moving (e.g. during transportation on aeroplane, or vehicles, ships, etc.). The invention relates to the above pharmaceutical compositions and a process for the preparation thereof.

Abstract translation: 通式I（其中R是氢或卤素）的化合物及其药学上可接受的酸加成盐适用于预防健康人或其他疾病时发生的不良和不利症状（例如出汗，恶心，呕吐，眩晕等） 哺乳动物受到异常移动（例如在飞机上运输，或车辆，船舶等）。 本发明涉及上述药物组合物及其制备方法。