公开(公告)号：WO1997015343A1

公开(公告)日：1997-05-01

申请号：PCT/AU1996000652

申请日：1996-10-17

Applicant: RESMED LIMITED ,  BRYDON, John, William, Ernest ,  WILLSON, Grant

Inventor： RESMED LIMITED

IPC: A61M16/00

CPC classification number: A61M16/0069 ,  A61M16/024 ,  A61M16/0858 ,  A61M2016/0021 ,  A61M2016/0036 ,  A61M2016/0039

Abstract: Apparatus for the supply of breathable gas cyclically at an inspiratory pressure and the lower expiratory pressure substantially in synchronism with a patient's (16) respiration is disclosed. A flow generator (10) is coupled to a gas delivery system (12) to deliver the breathable gas to the patient's airways. A motor controller (23) receives a signal (36) representing respiratory flow. A motor controller (23) outputs a control signal (24) has control over the electric motor (25) and thus the turbine (22) to generate the required inspiratory and expiratory pressures. The controller (23) detects transitions between inspiration and expiration from the flow signal (36) to discriminate between patient inspiration and expiration. A counter (58) counts a first time duration commenced from the last transition to inspiration, whereby if the first time duration elapses before a transition to expiration, the controller (23) causes the supply of the expiration pressure. Furthermore, another counter (62) counts a second time duration commenced from the last transition to inspiration that forces the turbine (22) to supply the inspiratory pressure until the second time duration elapses even if during the second time duration there is a transition to expiration by the patient.

Abstract translation: 公开了用于以吸气压力循环地供应透气性气体和与患者（16）呼吸基本上同步的较低呼气压力的装置。 流量发生器（10）联接到气体输送系统（12）以将可呼吸气体递送到患者的气道。 马达控制器（23）接收代表呼吸流量的信号（36）。 电动机控制器（23）输出具有对电动机（25）的控制的控制信号（24），从而输出涡轮（22）以产生所需的吸气和呼气压力。 控制器（23）从流量信号（36）检测吸气和呼气之间的转变，以区分患者的吸气和呼气。 计数器（58）对从上一次转换到吸气开始的第一时间段进行计数，从而如果在过渡到期之前经过了第一个持续时间，则控制器（23）引起提供呼气压力。 此外，另一个计数器（62）计算从上一次转换到启动的第二时间段，其强制涡轮机（22）提供吸气压力，直到第二持续时间过去，即使在第二持续时间期间过渡到期满 由病人

公开(公告)号：WO1997010868A1

公开(公告)日：1997-03-27

申请号：PCT/AU1996000586

申请日：1996-09-18

Applicant: RESMED LIMITED ,  BRYDON, John, William, Ernest ,  WICKHAM, Peter, John, Deacon ,  BACHAK, Miroslav ,  HOLLIS, Shane, Douglas

Inventor： RESMED LIMITED

IPC: A61M16/00

CPC classification number: A61M16/0057 ,  A61M16/0066 ,  Y10T137/2544 ,  Y10T137/86558

Abstract: The pressure of breathable gas exiting a flow generator (10) is controlled by adjusting the efficiency of the flow generator. In one embodiment, a baffle plate (44) of a control element (40) can restrict the open entry area of a motor (16) driven turbine (18) of the flow generator. In another form, the degree of opening of the mouth of the flow generator inlet (20), and hence the pneumatic impedance, can be controlled, as in a similar manner can the impedance outlet (22).

Abstract translation: 通过调节流量发生器的效率来控制离开流量发生器（10）的透气气体的压力。 在一个实施例中，控制元件（40）的挡板（44）可以限制流量发生器的电动机（16）驱动涡轮机（18）的打开进入区域。 在另一种形式中，流量发生器入口（20）的开口的程度以及因此的气动阻抗可以被控制，如同样的方式，阻抗出口（22）。

公开(公告)号：WO2003013355A1

公开(公告)日：2003-02-20

申请号：PCT/AU2002/001028

申请日：2002-08-02

Applicant: RESMED LIMITED ,  BRYDON, John, William, Ernest

Inventor： BRYDON, John, William, Ernest

IPC: A61B5/113

CPC classification number: A61B5/4818 ,  A61B5/113 ,  A61B5/6887 ,  A61B2562/0247 ,  A61B2562/043

Abstract: The use of diagnostic processing of signals derived from a respiratory analysis mattress (2) to determine the occurence of central apneas is disclosed. A plurality of sensor strips (5) supply electrical signals arising from localised displacement by a patient's body. The individual body effort (displacement) signals are converted into digital form and provided to a processor (104). The occurence of a central apnea is determined by a relative dimunition of the digitised body effort signals. In one form, dimunition is determined by a reduction in amplitude in excess of a predetermined threshold amount. Alternatively, dimunition is determined by forming a ratio of a reference average movement effort value and a contemporaneous movement effort value, and comparing the ratio against a threshold reference value. Advantageously, a further condition can be that there is also a predominant cyclic signal within the range of respiratory origin present.

Abstract translation: 公开了使用来自呼吸分析床垫（2）的信号的诊断处理来确定中枢呼吸暂停的发生。 多个传感器条（5）提供由患者身体的局部位移产生的电信号。 个体体力（位移）信号被转换成数字形式并提供给处理器（104）。 中枢性呼吸暂停的发生由数字化身体力量信号的相对调节度决定。 在一种形式中，通过超过预定阈值量的幅度减小来确定调光度。 或者，通过形成参考平均移动努力值和同时期移动努力值的比率，并将该比率与阈值参考值进行比较来确定调光度。 有利地，另外的条件可能是在呼吸起源范围内存在主要的循环信号。

公开(公告)号：WO1996032055A1

公开(公告)日：1996-10-17

申请号：PCT/AU1996000218

申请日：1996-04-11

Applicant: RESMED LIMITED ,  COLLA, Gregory, Alan ,  BRYDON, John, William, Ernest

Inventor： RESMED LIMITED

IPC: A61B05/00

CPC classification number: A61B5/4818 ,  A61B5/0205 ,  A61B5/0531 ,  A61B5/0816

Abstract: The occurrence of an arousal in a patient associated with an apneic or hypopneic episode can be determined. Sensors (10) are placed on a patient to obtain signals representative of at least two physiological variables, for example skin conductance, heart rate and blood oxygen concentration. The signals are conditioned by conditioning circuitry (12), then processed by a processor (18) to correlate at least two thereof. A coincident change in at least two of the processed signals is indicative of the occurrence of an arousal, that in turn indicates an apneic or hypopneic episode has occurred. A patient thus can be diagnosed as suffering conditions such as obstructive sleep apnea.

Abstract translation: 可以确定与呼吸暂停或呼吸不全发作相关的患者中的觉醒的发生。 将传感器（10）放置在患者身上以获得表示至少两个生理变量的信号，例如皮肤电导，心率和血氧浓度。 信号由调理电路（12）调节，然后由处理器（18）处理以使其至少两个相关。 至少两个处理过的信号中的重合变化表示发觉，这反过来表明发生呼吸暂停或呼吸不畅。 因此，可以将患者诊断为患有障碍性睡眠呼吸暂停等症状。

公开(公告)号：WO1996041571A1

公开(公告)日：1996-12-27

申请号：PCT/AU1996000347

申请日：1996-06-07

Applicant: RESMED LIMITED ,  BRYDON, John, William, Ernest ,  PICCIONE, Patrick, Manuel

Inventor： RESMED LIMITED

IPC: A61B05/087

CPC classification number: A61B5/097 ,  A61B5/087 ,  Y10S128/911

Abstract: A pair of nasal prongs (15), suitable for insertion into the lower portion of the nares, join together via a small plenum chamber (16) to form a single tube (17) conveying the nasal pressure towards an electrical pressure transducer (19). Another prong (20) is held in proximity with the patient's mouth. A baffle element (25) extends downwards from a location above the open end of the prong (20) to redirect a portion of oral airflow. The oral tube (21) extends towards the electrical pressure transducer (19), and conjoins with the nasal tube (17) at a junction (22) to form a common tube (18) connected to the pressure transducer (19). The relative lengths and/or diameters of the nasal tube (17) and the oral tube (21) are arranged so that the respective pneumatic impedances are different, so that the contributions of respiratory airflow from each of said tubes (17, 21) are substantially equal.

Abstract translation: 适于插入鼻孔下部的一对鼻尖（15）通过小的压力室16连接在一起以形成将鼻压传送到电压力传感器（19）的单个管（17） 。 另外一个分支（20）位于患者口附近。 挡板元件（25）从尖头（20）的开口端上方的位置向下延伸，以重新定向一部分口腔气流。 口管（21）朝向电压力传感器（19）延伸，并且在结（22）处与鼻管（17）结合，以形成连接到压力传感器（19）的公共管（18）。 鼻管（17）和口管（21）的相对长度和/或直径被布置成使得相应的气动阻抗不同，使得来自每个所述管（17,21）的呼吸气流的贡献为 基本相等

公开(公告)号：WO1989005606A1

公开(公告)日：1989-06-29

申请号：PCT/GB1988001138

申请日：1988-12-20

Applicant: ROYAL POSTGRADUATE MEDICAL SCHOOL ,  WERTHEIM, David, Frank, Philip ,  CONNELL, John, Anthony ,  OOZEER, Rowena, Carey ,  BRYDON, John, William, Ernest ,  DUBOWITZ, Victor

Inventor： ROYAL POSTGRADUATE MEDICAL SCHOOL

IPC: A61B05/04

CPC classification number: A61B5/0476

Abstract: A method for analysing an electro-encephalogram (EEG) and apparatus for implementing the method are described. Preferably EEG's from the left and right sides of the head are analysed together. An EEG is analysed by detecting the bursts of activity having amplitudes which exceed a threshold voltage and each burst of activity in the EEG is determined to have ended when it is followed by a quiescent period below the threshold voltage having a duration of, say, at least 6 seconds. The total time of all quiescent periods occurring within an epoch, for example, 10 minutes is then calculated and displayed. The apparatus may include a digital computer for effecting statistical analysis of the total times for many consecutive epochs. The computer may also be used in generating the total times. A graphical output representing the total times may be produced enabling the progress of a patient to be assessed rapidly.

Abstract translation: 描述用于分析脑电图（EEG）的方法和用于实现该方法的装置。 优选地，从头部的左侧和右侧分别分析脑电图。 通过检测具有超过阈值电压的幅度的活动脉冲串来分析EEG，并且当其后面是低于具有例如持续时间的持续时间的阈值电压的静止时段时，EEG中的每个活动突发被确定为已经结束 至少6秒钟。 然后计算并显示在时期内例如10分钟内发生的所有静止时段的总时间。 该装置可以包括数字计算机，用于对许多连续历元进行总时间的统计分析。 计算机也可用于产生总时间。 可以产生表示总时间的图形输出，使得能够快速评估患者的进展。

公开(公告)号：WO1997005824A1

公开(公告)日：1997-02-20

申请号：PCT/AU1996000500

申请日：1996-08-08

Applicant: RESMED LIMITED ,  BRYDON, John, William, Ernest ,  CAPPIUS, Hans-Joachim

Inventor： RESMED LIMITED

IPC: A61B05/087

CPC classification number: G01F1/28 ,  A61B5/0876 ,  A61B5/097

Abstract: Apparatus (40) for monitoring oro-nasal respiratory flow is disclosed. The apparatus (40) is formed of a curved plate (42) to which is substantially perpendicularly arranged a planar member (44), the plate (42) and the member (44) are connected by a neck portion (46). Mounted in an upstanding fashion from the planar member (44) are two nasal prongs (48, 50). Two PVDF sensors (60) are mounted from, and lie in, the plane of the planar member (44), co-operating with a respective nasal prong (48, 50). A further PVDF sensor (80) in planar form is arranged to be downwardly directed and perpendicular to the planar member (44) so as to be located in the vicinity of the mouth when the apparatus (40) is being worn by a patient. The PVDF sensors (60, 80) deflect respectively under the influence of nasal and oral airflow, and generate electrical charge having a determined relationship with the airflow.

Abstract translation: 公开了用于监测鼻呼吸流量的装置（40）。 该装置（40）由弯曲板（42）形成，平板构件（44）基本上垂直布置，板（42）和构件（44）通过颈部（46）连接。 从平面构件（44）以直立方式安装有两个鼻针（48,50）。 两个PVDF传感器（60）从平面构件（44）的平面安装并位于平面构件（44）的平面中，与相应的鼻尖（48,50）配合。 平面形式的另一个PVDF传感器（80）布置成向下指向并垂直于平面构件（44），以便当装置（40）被患者佩戴时位于嘴的附近。 PVDF传感器（60,80）分别在鼻腔和口腔气流的影响下偏转，并产生与气流具有确定关系的电荷。

公开(公告)号：WO1988002618A1

公开(公告)日：1988-04-21

申请号：PCT/GB1987000725

申请日：1987-10-15

Applicant: ROYAL POSTGRADUATE MEDICAL SCHOOL ,  COOMBS, Richard, Robert, Harvey ,  BRYDON, John, William, Ernest ,  BEVERLY, Michael

Inventor： ROYAL POSTGRADUATE MEDICAL SCHOOL

IPC: A61B17/18

CPC classification number: A61B17/8004 ,  A61B17/66 ,  A61B2017/00544

Abstract: An external fixator for use in the treatment of bone fractures comprises a pair of rigid body member 1a and 1b, each of the body members being provided with a plurality of mountings (24) for holding bone pins (25) securely relative to the associated body member after the bone pins have been inserted into a bone part, the body members being so interconnected as to permit only rectilinear relative movement between them, means (12) for applying, in use, a substantially constant force tending to urge the body members towards each other and means (19) for temporarily increasing the applied force above the constant value.

Abstract translation: 用于治疗骨折的外固定器包括一对刚体部件1a和1b，每个主体部件设置有多个安装件（24），用于相对于相关联的身体牢固地保持骨销（25） 在骨销已经插入骨头部分中之后，主体部件被互连，以便仅允许它们之间的直线相对运动，用于在使用中施加基本上恒定的力的装置（12） 彼此以及用于将所施加的力临时增加到恒定值以上的装置（19）。