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    MICROORGANISM PRODUCING 5'-XANTHYLIC ACID
    1.
    发明申请
    MICROORGANISM PRODUCING 5'-XANTHYLIC ACID 审中-公开
    生产5'-硫酸的微生物

    公开(公告)号：WO2004053110A1

    公开(公告)日：2004-06-24

    申请号：PCT/KR2003/002704

    申请日：2003-12-10

    Applicant: CJ CORPORATION ,  KWAG, Young-Hyeon ,  OH, Ki-Hoon ,  KIM, Jeong-Hwan ,  OH, Yoon-Suk ,  SIM, Jae-Ick ,  PARK, Young-Hoon ,  CHANG, Jea-Young

    Inventor： KWAG, Young-Hyeon ,  OH, Ki-Hoon ,  KIM, Jeong-Hwan ,  OH, Yoon-Suk ,  SIM, Jae-Ick ,  PARK, Young-Hoon ,  CHANG, Jea-Young

    IPC: C12N1/20

    CPC classification number: C12P17/182 ,  C12R1/15

    Abstract: The invention relates to Corynebacterium ammoniagenes CJXSP 0201 KCCM 10448 producing 5'-xanthylic acid. More specifically, the invention relates to Corynebacterium ammoniagenes CJXSP 0201 KCCM 10448 which is a mutant strain of Corynebacterium ammoniagenes KCCM 10340 having a resistance to osmotic pressure. In order to obtain mutant strain having enhanced respiratory activity, the present invention adopted Corynebacterium ammoniagenes KCCM 10340 as parent strain and treated it with UV radiation and mutation derivatives such as N-methyl-N'-nitro-n-nitrosoguanidine(NTG) according to ordinary procedure. Therefore, Corynebacterium ammoniagenes CJXSP 0201 KCCM 10448 of the present invention makes it possible to overcome growth-standing phase rapidly on early culture and for same period of fermentation, can accumulate 5'-xanthylic acid in culture medium at a high yield and concentration rate.

    Abstract translation: 本发明涉及产生5'-戊酸的产氨棒杆菌CJXSP 0201 KCCM 10448。 更具体地，本发明涉及具有抗渗透压的耐氨基酸棒杆菌KCCM 10340的突变菌株的产氨棒杆菌CJXSP 0201 KCCM 10448。 为了获得具有增强的呼吸活性的突变菌株，本发明使用产氨杆菌KCCM 10340作为亲本菌株，并用UV辐射和N-甲基-N'-硝基-N-亚硝基胍（NTG）等突变衍生物按照 普通程序。 因此，本发明的产氨酸棒杆菌CJXSP 0201 KCCM 10448可以在早期培养中快速克服生长稳定期，并且在相同的发酵期内，可以以高产率和浓度的速率在培养基中积累5'-叶酸。

    MICROORGANISM PRODUCING 5'XANTHYLIC ACID
    3.
    发明申请
    MICROORGANISM PRODUCING 5'XANTHYLIC ACID 审中-公开
    生产5'-羟乙酸的微生物

    公开(公告)号：WO2004053109A1

    公开(公告)日：2004-06-24

    申请号：PCT/KR2003/002703

    申请日：2003-12-10

    Applicant: CJ CORPORATION ,  KWAG, Young-Hyeon ,  OH, Ki-Hoon ,  KIM, Jeong-Hwan ,  OH, Yoon-Suk ,  SIM, Jae-Ick ,  PARK, Young-Hoon ,  CHANG, Jea-Young

    Inventor： KWAG, Young-Hyeon ,  OH, Ki-Hoon ,  KIM, Jeong-Hwan ,  OH, Yoon-Suk ,  SIM, Jae-Ick ,  PARK, Young-Hoon ,  CHANG, Jea-Young

    IPC: C12N1/20

    CPC classification number: C12P19/32 ,  C12P19/40 ,  C12R1/15

    Abstract: The invention relates to Corynebacterium ammoniagenes CJXOL 0201 KCCM 10447 producing 5'-xanthylic acid. More specifically, the invention relates to Corynebacterium ammoniagenes CJXOL 0201 KCCM 10447 which is a mutant strain of Corynebacterium ammoniagenes KCCM 10340 having a resistance to oligomycin. In order to obtain mutant strain having enhanced respiratory activity, the present invention adopted Corynebacterium ammoniagenes KCCM 10340 as parent strain and treated it with UV radiation and mutation derivatives such as N-methyl-N'-nitro-n-nitrosoguanidine(NTG) according to ordinary procedure. Therefore, Corynebacterium ammoniagenes CJXOL 0201 KCCM 10447 of the present invention makes it possible to increase ATP reproducing activity for same period of fermentation and can accumulate 5'xanthylic acid in culture medium at a high yield and concentration rate.

    Abstract translation: 本发明涉及产生5'-戊酸的产氨棒杆菌CJXOL 0201 KCCM 10447。 更具体地，本发明涉及产氨杆菌CJXOL 0201 KCCM 10447，它是具有对寡霉素抗性的产氨棒杆菌KCCM10340的突变菌株。 为了获得具有增强的呼吸活性的突变菌株，本发明使用产氨杆菌KCCM 10340作为亲本菌株，并用UV辐射和N-甲基-N'-硝基-N-亚硝基胍（NTG）等突变衍生物按照 普通程序。 因此，本发明的产氨酸棒杆菌CJXOL 0201 KCCM 10447可以在相同的发酵期内增加ATP的再生活性，并且可以以高产率和浓度的速率在培养基中积累5'-戊酸。

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