公开(公告)号：WO2010120926A1

公开(公告)日：2010-10-21

申请号：PCT/US2010/031092

申请日：2010-04-14

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC.

Inventor： BEREZ, Aaron Lee ,  TRAN, Quang, Quoc

IPC: A61F2/06

CPC classification number: A61F2/86 ,  A61B17/12118 ,  A61B2017/12054 ,  A61F2/852 ,  A61F2/90 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/9505 ,  A61F2002/9665 ,  A61F2230/0078 ,  A61F2230/0095 ,  A61F2250/0015 ,  A61F2250/0017 ,  A61F2250/0063

Abstract: Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatuses for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allow adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen- demanding tissues, are not deprived of the necessary blood flow. A plurality of stents, for example at least partially overlapping, can be used. Some embodiments describe various methods for confirming the occlusion of an aneurysm or for dislodging material from a vessel wall.

Abstract translation: 这里描述的是可以例如导航神经血管系统的曲折血管的柔性可植入闭塞装置。 闭塞装置还可以符合脉管系统的曲折血管的形状。 在一些实施例中，闭塞装置可引导血管内血流远离动脉瘤或限制血液流向动脉瘤。 一些实施例描述了用于沿着装置的长度调节闭塞装置的孔隙率的方法和装置。 在一些实施例中，闭塞装置允许向相邻结构提供足够的血液流动，使得这些结构，无论它们是分支血管还是需氧组织，都不会被剥夺必要的血流。 可以使用多个支架，例如至少部分重叠。 一些实施例描述用于确认动脉瘤闭塞或从血管壁移走材料的各种方法。

公开(公告)号：WO2007139689A3

公开(公告)日：2007-12-06

申请号：PCT/US2007/011551

申请日：2007-05-15

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC. ,  GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  BEREZ, Aaron, L.

Inventor： GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  BEREZ, Aaron, L.

IPC: A61F2/06

Abstract: A vascular occluding device for modifying blood flow in a vessel, while maintaining blood flow to the surrounding tissue. The occluding device includes a flexible, easily compressible and bendable occluding device that is particularly suited for treating aneurysms in the brain. The neurovascular occluding device can be deployed using a micro-catheter. The occluding device can be formed by braiding wires in a helical fashion and can have varying lattice densities along the length of the occluding device. The occluding device could also have different lattice densities for surfaces on the same radial plane.

公开(公告)号：WO2007139699A2

公开(公告)日：2007-12-06

申请号：PCT/US2007/011668

申请日：2007-05-16

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC. ,  GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  BEREZ, Aaron, L.

Inventor： GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  BEREZ, Aaron, L.

IPC: A61F2/06

CPC classification number: A61B17/12113 ,  A61B17/12022 ,  A61B17/12118 ,  A61B2017/1205 ,  A61F2/90 ,  A61F2002/823 ,  A61F2230/0078 ,  A61F2230/0091 ,  A61F2230/0095

Abstract: A vascular occluding device for modifying blood flow in a vessel, while maintaining blood flow to the surrounding tissue. The occluding device includes a flexible, easily compressible and bendable occluding device that is particularly suited for treating aneurysms in the brain. The neurovascular occluding device can be deployed using a micro-catheter. The occluding device can be formed by braiding wires in a helical fashion and can have varying lattice densities, along the length of the occluding device. The occluding device could also have different lattice densities for surfaces on the same radial plane.

Abstract translation: 一种血管阻塞装置，用于改变血管中的血流，同时保持血液流向周围组织。 闭塞装置包括柔性，易压缩和可弯曲的闭塞装置，其特别适用于治疗脑中的动脉瘤。 可以使用微导管部署神经血管闭塞装置。 闭塞装置可以通过以螺旋方式编织线而形成，并且可以沿着闭塞装置的长度具有变化的晶格密度。 闭塞装置对于同一径向平面上的表面也可以具有不同的晶格密度。

公开(公告)号：WO2010123831A1

公开(公告)日：2010-10-28

申请号：PCT/US2010/031643

申请日：2010-04-19

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC.

Inventor： GARCIA, Adrian ,  GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Quoc ,  BEREZ, Aaron, Lee

IPC: A61F2/06

CPC classification number: A61B17/12109 ,  A61B17/12022 ,  A61B17/12118 ,  A61B2017/12054 ,  A61M25/09 ,  A61M2025/0042 ,  A61M2025/0681 ,  A61M2025/09083 ,  A61M2025/0915 ,  A61M2025/09183

Abstract: Systems, assemblies, and methods for deploying an occluding device that can be used to remodel an aneurysm within the vessel by, for example, neck reconstruction or balloon remodeling. The system can comprise an introducer sheath and an assembly for carrying the occluding device. The assembly can include an elongated flexible member having an occluding device retaining member for receiving a first end of the occluding device, a proximally positioned retaining member for engaging a second end of the occluding device and a support surrounding a portion of the elongated flexible member over which the occluding device can be positioned. The elongated flexible member can form a coil portion.

Abstract translation: 用于部署闭塞装置的系统，组件和方法，其可以用于通过例如颈部重建或气囊重塑来改造血管内的动脉瘤。 该系统可以包括导引器鞘和用于携带闭塞装置的组件。 组件可以包括细长的柔性构件，其具有用于接收闭塞装置的第一端的闭塞装置保持构件，用于接合闭塞装置的第二端的近侧定位的保持构件和围绕细长柔性构件的一部分的支撑件 闭塞装置可以被定位。 细长的柔性构件可以形成线圈部分。

公开(公告)号：WO2008063156A2

公开(公告)日：2008-05-29

申请号：PCT/US2006/041695

申请日：2006-10-26

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC. ,  GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  PIPLANI, Alec ,  BEREZ, Aaron, L. ,  BOJANOWSKI, Bart

Inventor： GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  PIPLANI, Alec ,  BEREZ, Aaron, L. ,  BOJANOWSKI, Bart

IPC: A61B17/22

CPC classification number: A61B17/221 ,  A61B2017/2215

Abstract: An intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tube member having a distal end portion. An elongated core member is disposed with the interior cavity of the tubular member for rotational or slidably movement within the tubular member and the elongated core member having a proximal end portion and a distal end portion. The elongated core member comprises a uniform diameter tube having some flexibility at the proximal end portion and greater flexibility while along a longitudinal axis in a direction towards the distal end portion; and a grasping configuration is provided for capturing an object (e.g., clot or debris) therein and the assembly may have a proximal end secured to the distal end of the elongated core member. The configuration has an expanded and contracted configuration, and distal sections configured to grasp an object. The grasping configuration may be formed by at least one movable jaw attached to the distal end portion of the elongated core member and a length portion of the distal end portion of the tube member. The grasping configuration may include unitarily formed plurality of movable jaws attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by a plurality of loop members attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen. The device has the spiral member provided at the distal end portion of the elongated core member. The grasping configuration can be formed by at least one web member for retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.

Abstract translation: 体内抓握装置包括用于进入人体内腔的管状构件和具有远端部分的管构件。 细长的芯构件设置有管状构件的内部空腔，用于在管状构件内旋转或可滑动地移动，并且细长的芯构件具有近端部分和远端部分。 细长的芯构件包括均匀直径的管，其在近端部分具有一些柔性，并且在朝向远端部分的方向上沿着纵向轴线具有更大的柔性; 并且提供抓握构造用于捕获其中的物体（例如，凝块或碎屑），并且组件可以具有固定到细长芯构件的远端的近端。 该配置具有扩展和收缩配置，并且远端部分配置为抓住对象。 夹持构造可以由附接到细长芯构件的远端部分的至少一个可动夹爪和管构件的远端部分的长度部分形成。 抓持构造可以包括连接到细长芯构件的远端部分的一体形成的多个可动爪。 此外，抓持构造可以由附接到细长芯构件的远端部的多个环构件形成。 此外，抓持构造可以由至少一个螺旋构件形成，该至少一个螺旋构件具有用于穿透要从人体腔去除的物体的远端。 该装置具有设置在细长芯部件的远端部分的螺旋部件。 抓持构造可以由至少一个腹板构件形成，用于将要从人体腔移除的物体保持在该细长的芯构件的远端部。

公开(公告)号：WO2007139698A2

公开(公告)日：2007-12-06

申请号：PCT/US2007/011666

申请日：2007-05-16

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC. ,  GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  BEREZ, Aaron, L.

Inventor： GARCIA, Adrian ,  YE, Ting, Tina ,  TRAN, Quang, Q. ,  BEREZ, Aaron, L.

IPC: A61F2/06

CPC classification number: A61F2/966 ,  A61B17/12022 ,  A61B17/12118 ,  A61B2017/12054 ,  A61F2/95

Abstract: A system and method for deploying an occluding device that can be used to remodel an aneurysm within the vessel by, for example, neck reconstruction or balloon remodeling. The system comprises an introducer sheath and an assembly for carrying the occluding device. The assembly includes an elongated flexible member having an occluding device retaining member for receiving a first end of the occluding device, a proximalIy positioned retaining member for engaging a second end of the occluding device and a support surrounding a portion of the elongated flexible member over which the occluding device can be positioned.

Abstract translation: 一种用于部署闭塞装置的系统和方法，所述闭塞装置可用于通过例如颈部重建或气囊重塑来改造血管内的动脉瘤。 该系统包括导引鞘和用于携带闭塞装置的组件。 组件包括细长的柔性构件，其具有用于接收闭塞装置的第一端的闭塞装置保持构件，用于接合闭塞装置的第二端的近端定位的保持构件和围绕细长柔性构件的一部分的支撑件， 可以定位闭塞装置。

公开(公告)号：WO2006127005A1

公开(公告)日：2006-11-30

申请号：PCT/US2005/018441

申请日：2005-05-25

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC. ,  BEREZ, Aaron, Lee ,  TRAN, Quang, Quoc

Inventor： BEREZ, Aaron, Lee ,  TRAN, Quang, Quoc

IPC: A61F2/06

CPC classification number: A61F2/966 ,  A61B17/12022 ,  A61B17/12118 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61F2/90 ,  A61F2002/823 ,  A61F2002/9665

Abstract: A system and method for deploying an occluding device that can be used to remodel an aneurysm within the vessel by, for example, neck reconstruction or balloon remodeling. The system comprises an introducer sheath and an assembly for carrying the occluding device. The assembly includes an elongated flexible member having an occluding device retaining member for receiving a first end of the occluding device, a proximally positioned retaining member for engaging a second end of the occluding device and a support surrounding a portion of the elongated flexible member over which the occluding device can be positioned.

Abstract translation: 一种用于部署闭塞装置的系统和方法，所述闭塞装置可用于通过例如颈部重建或气囊重塑来改造血管内的动脉瘤。 该系统包括导引鞘和用于携带闭塞装置的组件。 组件包括细长的柔性构件，其具有用于接收闭塞装置的第一端的闭塞装置保持构件，用于接合闭塞装置的第二端的近端定位的保持构件和围绕细长柔性构件的一部分的支撑件， 可以定位闭塞装置。

公开(公告)号：WO2005115118A2

公开(公告)日：2005-12-08

申请号：PCT/US2005/018442

申请日：2005-05-25

Applicant: CHESTNUT MEDICAL TECHNOLOGIES, INC. ,  BEREZ, Aaron, Lee ,  TRAN, Quang, Quoc

Inventor： BEREZ, Aaron, Lee ,  TRAN, Quang, Quoc

IPC: A61B17/12 ,  A61F2/82 ,  A61F2/90

CPC classification number: A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61F2/90 ,  A61F2002/823 ,  A61F2230/001 ,  A61F2230/0078 ,  A61F2230/0091 ,  A61F2230/0095

Abstract: A vascular occluding device for modifying blood flow in a vessel, while maintaining blood flow to the surrounding tissue. The occluding device includes a flexible, easily compressible and bendable occluding device that is particularly suited for treating aneurysms in the brain. The neurovascular occluding device and be deployed using a micro-catheter. The occluding device can be formed braiding wires in a helical fashion and can have varying lattice densities along the length of the occluding device. The occluding device could also have different lattice densities for surfaces on the same radial plane.

Abstract translation: 一种血管阻塞装置，用于改变血管中的血流，同时保持血液流向周围组织。 闭塞装置包括柔性，易压缩和可弯曲的闭塞装置，其特别适用于治疗脑中的动脉瘤。 神经血管闭塞装置并使用微导管部署。 闭塞装置可以以螺旋方式形成编织线，并且沿着阻塞装置的长度可以具有变化的晶格密度。 闭塞装置对于同一径向平面上的表面也可以具有不同的晶格密度。