公开(公告)号：WO2004002510A1

公开(公告)日：2004-01-08

申请号：PCT/EP2003/006817

申请日：2003-06-27

Applicant: FACULTE UNIVERSITAIRE DES SCIENCES AGRONOMIQUES DE GEMBLOUX ,  UNIVERSITE DE LIEGE INTERFACE EMTREPRISES- UNIVERSITE ,  DELEU, Magali ,  BRASSEUR, Robert ,  PAQUOT, Michel ,  LEGROS, Hervé ,  DUFOUR, Samuel ,  JACQUES, Philippe ,  DESTAIN, Jacqueline ,  THONART, Philippe ,  BRANS, Alain ,  JORIS, Bernard ,  FRERE, Jean-Marie

Inventor： DELEU, Magali ,  BRASSEUR, Robert ,  PAQUOT, Michel ,  LEGROS, Hervé ,  DUFOUR, Samuel ,  JACQUES, Philippe ,  DESTAIN, Jacqueline ,  THONART, Philippe ,  BRANS, Alain ,  JORIS, Bernard ,  FRERE, Jean-Marie

IPC: A61K38/12

CPC classification number: C07K7/06 ,  A61K38/12 ,  C07K14/195 ,  C07K14/24 ,  C07K14/32 ,  C07K14/37

Abstract: The present invention relates to the use of lipopeptide preparations as anti-titled-peptide agent, which are able to inhibit or limit de destabilisation effect of tilted peptides on hydrophobic/hydrophilic interfaces, for instance on membranes. The lipopeptides comprise surfactins, iturins, and fengycins. It also relates to a process for the production of the lipopeptide preparations.

Abstract translation: 本发明涉及脂肽制剂作为抗标题肽试剂的用途，其能够抑制或限制倾斜肽对疏水/亲水界面（例如膜）上的去稳定作用。 脂肽包括表面活性素，神经蛋白和风味蛋白。 它还涉及生产脂肽制剂的方法。