公开(公告)号：WO2008073298A3

公开(公告)日：2008-08-28

申请号：PCT/US2007025077

申请日：2007-12-07

Applicant: UNITED COLOR MFG INC ,  FREDERICO JUSTIN J ,  DESAI BHARAT ,  SMITH MICHAEL J ,  HINTON MICHAEL P

Inventor： FREDERICO JUSTIN J ,  DESAI BHARAT ,  SMITH MICHAEL J ,  HINTON MICHAEL P

IPC: G01N37/00

CPC classification number: C10L1/003 ,  A61K31/343 ,  A61K2300/00

Abstract: The present invention is directed to a mixture of at least two different alkylated phenolphthalein ester compounds. Specifically, the present invention is directed to a mixture of at least two different compounds of formula I: wherein R 1 mixtures of aromatic esters for marking or tagging organic products, marker compositions comprising the same and manufacturing methods thereof represents a straight chain alkyl group having 1 to 11 carbon atoms; R 2 represents a hydrogen atom or a group of the formula C(O)R 4 where R 4 is a hydrogen atom or a straight chain alkyl group having 1 to 11 carbon atoms; X2 - X5 independently represent hydrogen; X6 - X13 is same or different, and represents hydrogen or a straight or branched chain alkyl group having 1 to 12 carbon atoms. It further relates to a marker composition containing said mixtures dissolved in a solvent.

Abstract translation: 本发明涉及至少两种不同的烷基化酚酞酯化合物的混合物。 具体而言，本发明涉及至少两种不同的式I化合物的混合物：其中用于标记或标记有机产物的芳族酯的混合物，包含其的标记物组合物及其制备方法 表示具有1至11个碳原子的直链烷基; R 2代表氢原子或式C（O）R 4的基团，其中R 4是氢原子或直链 具有1至11个碳原子的烷基; X2-X5独立地表示氢; X 6〜X 13相同或不同，表示氢或碳原子数1〜12的直链状或支链状的烷基。 它还涉及包含溶解在溶剂中的所述混合物的标记组合物。

公开(公告)号：WO2008011018A3

公开(公告)日：2008-06-26

申请号：PCT/US2007016185

申请日：2007-07-17

Applicant: ORTHOHELIX SURGICAL DESIGNS ,  DUCHARME DUSTIN ,  DEN HARTOG BRYAN D ,  MCGLAMRY MICHAEL C ,  DESAI BHARAT M ,  KAY DAVID B ,  STRNAD LEE A

Inventor： DUCHARME DUSTIN ,  DEN HARTOG BRYAN D ,  MCGLAMRY MICHAEL C ,  DESAI BHARAT M ,  KAY DAVID B ,  STRNAD LEE A

IPC: A61B17/58

CPC classification number: A61B17/8061 ,  A61B17/8057

Abstract: The present invention is a fully contoured calcaneal plate having substantially no planar surfaces except at the origin. The contoured plate includes radiused sections, one extending inferior to superior is curved inferior to superior in a shape which is close to cylindrical and which approximates the shape of the cuboid bone. The second radiused section is curved in the vicinity of the anterior strut, and in particular at the inferior portion of the plate, to accommodate the peroneal tubercle. The plate has a rectangular or modified ovoid body section and a dog boned shaped tail with triangular placed holes for fixation.

Abstract translation: 本发明是完全成型的跟骨板，其基本上没有平面，除了原点。 轮廓板包括圆形部分，一个延伸到上部的部分弯曲成较接近圆柱形并且近似长方体形状的上部的上部。 第二弧形部分在前支柱附近弯曲，特别是在板的下部弯曲，以适应腓骨结节。 该板具有矩形或修改的卵形体部分，并且具有三角形放置的孔用于固定的狗骨形尾部。

公开(公告)号：WO2008011018A2

公开(公告)日：2008-01-24

申请号：PCT/US2007/016185

申请日：2007-07-17

Applicant: ORTHOHELIX SURGICAL DESIGNS, INC. ,  DUCHARME, Dustin ,  DEN HARTOG, Bryan D. ,  MCGLAMRY, Michael C. ,  DESAI, Bharat M. ,  KAY, David B. ,  STRNAD, Lee A.

Inventor： DUCHARME, Dustin ,  DEN HARTOG, Bryan D. ,  MCGLAMRY, Michael C. ,  DESAI, Bharat M. ,  KAY, David B. ,  STRNAD, Lee A.

IPC: A61B17/58

CPC classification number: A61B17/8061 ,  A61B17/8057

Abstract: The present invention is a fully contoured calcaneal plate having substantially no planar surfaces except at the origin. The contoured plate includes radiused sections, one extending inferior to superior is curved inferior to superior in a shape which is close to cylindrical and which approximates the shape of the cuboid bone. The second radiused section is curved in the vicinity of the anterior strut, and in particular at the inferior portion of the plate, to accommodate the peroneal tubercle. The plate has a rectangular or modified ovoid body section and a dog boned shaped tail with triangular placed holes for fixation.

Abstract translation: 本发明是完全仿形的跟骨板，除了原点之外基本上没有平面。 成形板包括圆角部分，其中一个向下延伸的部分弯曲成向下弯曲成靠近圆柱形并接近长方体骨形状的形状。 第二圆角部分在前支柱附近弯曲，特别是在板的下部，以容纳腓骨结节。 该板有一个矩形或改进的卵形体部分和一个狗骨头形状的尾巴，三角形放置孔用于固定。

公开(公告)号：WO2008073298A2

公开(公告)日：2008-06-19

申请号：PCT/US2007/025077

申请日：2007-12-07

Applicant: UNITED COLOR MANUFACTURING, INC. ,  FREDERICO, Justin, J. ,  DESAI, Bharat ,  SMITH, Michael, J. ,  HINTON, Michael, P.

Inventor： FREDERICO, Justin, J. ,  DESAI, Bharat ,  SMITH, Michael, J. ,  HINTON, Michael, P.

IPC: G01N37/00

CPC classification number: C10L1/003 ,  A61K31/343 ,  A61K2300/00

Abstract: The present invention is directed to a mixture of at least two different alkylated phenolphthalein ester compounds. Specifically, the present invention is directed to a mixture of at least two different compounds of formula I: wherein R 1 mixtures of aromatic esters for marking or tagging organic products, marker compositions comprising the same and manufacturing methods thereof represents a straight chain alkyl group having 1 to 11 carbon atoms; R 2 represents a hydrogen atom or a group of the formula C(O)R 4 where R 4 is a hydrogen atom or a straight chain alkyl group having 1 to 11 carbon atoms; X2 - X5 independently represent hydrogen; X6 - X13 is same or different, and represents hydrogen or a straight or branched chain alkyl group having 1 to 12 carbon atoms. It further relates to a marker composition containing said mixtures dissolved in a solvent.

Abstract translation: 本发明涉及至少两种不同的烷基化酚酞化合物的混合物。 具体地说，本发明涉及至少两种不同的式I化合物的混合物：其中用于标记或标记有机产物的芳族酯的R 1 O 1混合物，包含其的标记组合物及其制备方法 表示碳原子数为1〜11的直链烷基。 R 2表示氢原子或式C（O）R 4的基团，其中R 4是氢原子或直链 具有1至11个碳原子的烷基; X2-X5独立地表示氢; X 6 -X 13相同或不同，表示氢或碳原子数1〜12的直链或支链烷基。 它还涉及含有溶解在溶剂中的所述混合物的标记组合物。

公开(公告)号：WO2010082111A1

公开(公告)日：2010-07-22

申请号：PCT/IB2010/000042

申请日：2010-01-12

Applicant: CADILA PHARMACEUTICALS LTD. ,  SODAGAR, Keval, Rameshchandra ,  MALIK, Vineet ,  DESAI, Bharat, Ramchandra ,  JAIN, Sudhir, Hukamchand ,  PARIKH, Sanjay, Natvarlal ,  SHARMA, Arun, Omprakash ,  BAPAT, Uday, Rajaram ,  KHAMAR, Bakulesh, Mafatlal

Inventor： SODAGAR, Keval, Rameshchandra ,  MALIK, Vineet ,  DESAI, Bharat, Ramchandra ,  JAIN, Sudhir, Hukamchand ,  PARIKH, Sanjay, Natvarlal ,  SHARMA, Arun, Omprakash ,  BAPAT, Uday, Rajaram ,  KHAMAR, Bakulesh, Mafatlal

IPC: C07D471/00

CPC classification number: C07D471/02

Abstract: The invention relates to an improved process for preparation of 3-(2-hydroxy ethyl)-9- hydroxy-2-methyl-4 H -pyrido[1,2-a]pyrimidin-4-one or its acid addition salt and its conversion to paliperidone or its acid addition salt without involving the use of an acid catalyst.

Abstract translation: 本发明涉及一种制备3-（2-羟基乙基）-9-羟基-2-甲基-4H-吡啶并[1,2-a]嘧啶-4-酮或其酸加成盐的改进方法及其转化率 至帕培酮或其酸加成盐，而不涉及使用酸催化剂。