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公开(公告)号:WO2008094849A2
公开(公告)日:2008-08-07
申请号:PCT/US2008/052165
申请日:2008-01-28
Applicant: UNITED THERAPEUTICS CORPORATION , DWEK, Raymond, Allen , SCANLAN, Christopher , DUNLOP, David, Cameron , MANSAB, Fatma, Mii , TULLY, Sarah, Erin , WENTWORTH, Paul , ZITZMANN, Nicole
Inventor: DWEK, Raymond, Allen , SCANLAN, Christopher , DUNLOP, David, Cameron , MANSAB, Fatma, Mii , TULLY, Sarah, Erin , WENTWORTH, Paul , ZITZMANN, Nicole
CPC classification number: A61K39/21 , A61K39/12 , A61K39/385 , A61K2039/6087 , A61K2039/645 , C07K14/005 , C12N2740/16122 , C12N2740/16134
Abstract: Disclosed are compositions and methods useful for inducing an immunogenic response in a subject or host. In particular, the compositions and methods may be directed to carbohydrate HIV vaccines and to methods of producing a carbohydrate HIV vaccine by introducing antigenic sugars into mimics of the glycans of the HIV envelope glycoproteins gpl20 and gp41.
Abstract translation: 公开了可用于在受试者或宿主中诱导免疫原性应答的组合物和方法。 特别地,组合物和方法可以涉及碳水化合物HIV疫苗,并且涉及通过将抗原性糖引入HIV包膜糖蛋白gp120和gp41的聚糖的模拟物中来产生碳水化合物HIV疫苗的方法。 p>
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公开(公告)号:WO2008094849A3
公开(公告)日:2008-12-31
申请号:PCT/US2008052165
申请日:2008-01-28
Applicant: UNITED THERAPEUTICS CORP , DWEK RAYMOND ALLEN , SCANLAN CHRISTOPHER , DUNLOP DAVID CAMERON , MANSAB FATMA MII , TULLY SARAH ERIN , WENTWORTH PAUL , ZITZMANN NICOLE
Inventor: DWEK RAYMOND ALLEN , SCANLAN CHRISTOPHER , DUNLOP DAVID CAMERON , MANSAB FATMA MII , TULLY SARAH ERIN , WENTWORTH PAUL , ZITZMANN NICOLE
IPC: A61K39/21
CPC classification number: A61K39/21 , A61K39/12 , A61K39/385 , A61K2039/6087 , A61K2039/645 , C07K14/005 , C12N2740/16122 , C12N2740/16134
Abstract: Disclosed are compositions and methods useful for inducing an immunogenic response in a subject or host. In particular, the compositions and methods may be directed to carbohydrate HIV vaccines and to methods of producing a carbohydrate HIV vaccine by introducing antigenic sugars into mimics of the glycans of the HIV envelope glycoproteins gpl20 and gp41.
Abstract translation: 公开了用于在受试者或宿主中诱导免疫原性应答的组合物和方法。 特别地,组合物和方法可以涉及碳水化合物HIV疫苗,以及通过将抗原性糖引入HIV包膜糖蛋白gp120和gp41的聚糖的模拟物来生产碳水化合物HIV疫苗的方法。
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