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    REAGENT AND METHOD FOR PROVIDING COATINGS ON SURFACES
    5.
    发明申请
    REAGENT AND METHOD FOR PROVIDING COATINGS ON SURFACES 审中-公开
    用于提供表面涂层的试剂和方法

    公开(公告)号：WO2003055611A1

    公开(公告)日：2003-07-10

    申请号：PCT/US2002/041143

    申请日：2002-12-20

    申请人： SURMODICS, INC. ,  CHAPPA, Ralph A. ,  STUCKE, Sean M. ,  AMOS, Richard A. ,  EVERSON, Terrence P. ,  CHUDZIC, Stephen J. ,  SWAN, Dale G. ,  DUQUETTE, Peter H.

    发明人： CHAPPA, Ralph A. ,  STUCKE, Sean M. ,  AMOS, Richard A. ,  EVERSON, Terrence P. ,  CHUDZIC, Stephen J. ,  SWAN, Dale G. ,  DUQUETTE, Peter H.

    IPC分类号： B05D1/36

    CPC分类号： B82Y30/00 ,  A61L27/34 ,  C09D4/00 ,  Y10S522/904 ,  Y10T428/249991 ,  Y10T428/249992 ,  C08F220/56 ,  C08F220/54

    摘要： A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a performed, and particularly a porous, polymeric substrate. The method includes the steps of a)- providing a porous support surface, b)- providing a nonpolymeric grafting reagent comprising a photoinitator group, c)- providing one or more polymerizable monomers adapted to be contacted with the surface, in the presence of the grafting reagent, and to be polymerized upon activation of the photoinitiator; and d)- applying the grafting reagent and monomer(s) to the surface in a manner, and under conditions, suitable to coat the surface with the grafting reagent and to cause the polymerization of monomers to the surface upon activation of the grafting reagent.

    摘要翻译： 一种接枝试剂和相关方法，其以提供和/或保留所需性质如表面孔隙的方式使用试剂在支撑表面上形成聚合物层，特别是多孔载体表面。 试剂和方法可以用于提供具有所需性质的薄的，顺应的，均匀的未交联的涂层，其在所执行的，特别是多孔的聚合物基材的表面上。 该方法包括以下步骤：a。提供多孔载体表面，b-提供包含光引发剂基团的非聚合接枝试剂，c-在接枝试剂存在下，提供适于与表面接触的一种或多种可聚合单体， 并且在激活光引发剂时聚合，并且以接枝试剂的方式和条件下将接枝试剂和单体施用到表面，并且在适合于用接枝剂涂覆表面的条件下并且在活化时使单体聚合到表面 的接枝试剂。

    WATER SOLUBLE CROSS-LINKING AGENTS
    8.
    发明申请
    WATER SOLUBLE CROSS-LINKING AGENTS 审中-公开
    水溶性交联剂

    公开(公告)号：WO1997016544A1

    公开(公告)日：1997-05-09

    申请号：PCT/US1996017645

    申请日：1996-10-31

    申请人： BSI CORPORATION ,  SWAN, Dale, G. ,  AMOS, Richard, A. ,  EVERSON, Terrence, P.

    发明人： BSI CORPORATION

    IPC分类号： C12N11/00

    CPC分类号： C07D295/112 ,  C07C45/63 ,  C07C225/16 ,  C07C309/14 ,  C07K17/06 ,  G01N33/54353 ,  Y10S530/81 ,  Y10S530/816 ,  C07C49/813

    摘要： A chemical linking agent formed of a di- or higher functional photoactivatable compound and providing at least one group that is charged under the conditions of use in order to provide improved water solubility. The linking agent further provides two or more photoactivatable groups in order to allow the agent to be used as a cross-linking agent in aqueous systems. The charged group can be provided by a radical that includes one or more salts of organic acids, onium compounds, or protonated amines (and optionally one or more additional photoreactive group), and the photoreactive groups can be provided by two or more radicals that include an aryl ketone.

    摘要翻译： 由二官能或更高官能的可光活化化合物形成的化学连接剂，并提供至少一个在使用条件下加入以提供改善的水溶性的基团。 连接剂还提供两个或更多个可光活化基团，以便允许该试剂在含水体系中用作交联剂。 带电基团可以由包括一种或多种有机酸，鎓化合物或质子化胺（和任选的一种或多种另外的光反应性基团）的盐的基团提供，并且光反应性基团可以由两个或更多个基团提供，所述基团包括 芳基酮。