MICROPOROUS ARTICLES COMPRISING BIODEGRADABLE MEDICAL POLYMERS, METHOD OF PREPARATION THEREOF AND METHOD OF USE THEREOF
    4.
    发明申请
    MICROPOROUS ARTICLES COMPRISING BIODEGRADABLE MEDICAL POLYMERS, METHOD OF PREPARATION THEREOF AND METHOD OF USE THEREOF 审中-公开
    包含生物可降解医用聚合物的微型制品及其制备方法及其使用方法

    公开(公告)号:WO2004087797A1

    公开(公告)日:2004-10-14

    申请号:PCT/CA2004/000500

    申请日:2004-04-02

    IPC分类号: C08J9/00

    摘要: The present invention relates to a highly controlled method of preparation of a microporous biodegradable polymeric article. Firstly, at least one biodegradable polymer A, one polymer B, biodegradable or not, partially or totally immiscible with A, and a compatibilizer C for A and B are selected. Secondly, the selected polymers are melt-blended, thereby preparing a polymer blend, wherein said polymers A and B have an essentially continuous morphology. Thirdly, after cooling, polymer B and compatibilizer C are selectively extracted from the polymer blend by dissolution in a solvent that is a non-solvent of polymer A. The resulting polymeric article has an essentially continuous porosity with a void volume between 10 and 90% and a unimodal diameter distribution set to a predefined unimodal peak location. It can be used in tissue engineering, for controlled release applications or as an implantable medical device.

    摘要翻译: 本发明涉及高度可控制的微孔可生物降解聚合物制品的方法。 首先,选择至少一种可生物降解的聚合物A,一种可生物降解的或不与A部分或完全不混溶的聚合物B,以及用于A和B的增容剂C。 其次,将所选择的聚合物熔融共混,从而制备聚合物共混物,其中所述聚合物A和B具有基本连续的形态。 第三,冷却后,通过溶解在聚合物A的非溶剂的溶剂中,从聚合物共混物中选择性地提取聚合物B和增容剂C.所得的聚合物制品具有基本上连续的孔隙率,空隙体积为10至90% 和单峰直径分布设置为预定义的单峰峰位置。 它可用于组织工程,控制释放应用或植入式医疗设备。

    THERMOPLASTIC STARCH AND SYNTHETIC POLYMER BLENDS AND METHOD OF MAKING
    5.
    发明申请
    THERMOPLASTIC STARCH AND SYNTHETIC POLYMER BLENDS AND METHOD OF MAKING 审中-公开
    热塑性淀粉和合成聚合物共混物及其制备方法

    公开(公告)号:WO2006116861A1

    公开(公告)日:2006-11-09

    申请号:PCT/CA2006/000695

    申请日:2006-04-28

    IPC分类号: C08L3/02 C08J5/22

    摘要: Disclosed herein is a composition of matter comprising a blend of discontinuous thermoplastic starch domains in a synthetic polymer, said composition of matter being characterized by an average diameter of thermoplastic starch domains of about 0.2 to about 1.5 microns. Also disclosed are compositions of matter comprising a blend of discontinuous thermoplastic starch domains in a synthetic polymer and being characterized by finished articles having key mechanical properties which are essentially maintained or in some cases improved over pure synthetic polymers. In yet another aspect, the present invention provides a method for making the material of the present invention. In a related aspect, the present invention provides the novel materials issued from the method of making the material. In other aspects, the present invention provides novel finished article compositions in the form of films or molded articles.

    摘要翻译: 本文公开了一种物质组合物,其包含合成聚合物中不连续热塑性淀粉结构域的共混物,所述物质组合物的特征在于热塑性淀粉结构域的平均直径为约0.2至约1.5微米。 还公开了包含合成聚合物中的不连续热塑性淀粉结构域的共混物的物质组合物,其特征在于具有主要机械性能的成品,其基本上保持或在某些情况下比纯合成聚合物改进。 另一方面,本发明提供了制造本发明材料的方法。 在有关方面,本发明提供从制造该材料的方法发出的新型材料。 在其它方面,本发明提供了薄膜或模制品形式的新型成品制品。