公开(公告)号：WO2009002808A3

公开(公告)日：2009-07-23

申请号：PCT/US2008067571

申请日：2008-06-19

申请人： ARQULE INC ,  LIU JIFENG ,  ALI SYED M ,  ASHWELL MARK A ,  YE PING ,  GUAN YOUSHENG ,  NG SHI-CHUNG ,  PALMA ROCIO ,  YOHANNES DAN

发明人： LIU JIFENG ,  ALI SYED M ,  ASHWELL MARK A ,  YE PING ,  GUAN YOUSHENG ,  NG SHI-CHUNG ,  PALMA ROCIO ,  YOHANNES DAN

IPC分类号： C07D239/90 ,  A61K31/517 ,  A61P35/00

CPC分类号： C07D239/90

摘要： The present invention relates to quinazolinone compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising the quinazolinone compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a quinazolinone compound of the present invention

摘要翻译： 本发明涉及喹唑啉酮化合物及其制备方法。 本发明还涉及包含喹唑啉酮化合物的药物组合物。 本发明提供了通过向有需要的受试者施用治疗有效量的本发明的喹唑啉酮化合物来治疗细胞增殖性疾病如癌症的方法

公开(公告)号：WO2009002808A2

公开(公告)日：2008-12-31

申请号：PCT/US2008/067571

申请日：2008-06-19

申请人： ARQULE, INC. ,  LIU, Jifeng ,  ALI, Syed, M. ,  ASHWELL, Mark, A. ,  YE, Ping ,  GUAN, Yousheng ,  NG, Shi-chung ,  PALMA, Rocio ,  YOHANNES, Dan

发明人： LIU, Jifeng ,  ALI, Syed, M. ,  ASHWELL, Mark, A. ,  YE, Ping ,  GUAN, Yousheng ,  NG, Shi-chung ,  PALMA, Rocio ,  YOHANNES, Dan

IPC分类号： C07D239/90 ,  A61K31/517 ,  A61P35/00

CPC分类号： C07D239/90

摘要： The present invention relates to quinazolinone compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising the quinazolinone compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a quinazolinone compound of the present invention

摘要翻译： 本发明涉及喹唑啉酮化合物及其制备方法。 本发明还涉及包含喹唑啉酮化合物的药物组合物。 本发明提供了通过向有需要的受试者施用治疗有效量的本发明的喹唑啉酮化合物来治疗细胞增殖性疾病如癌症的方法