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1.BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN ENGINEERED BACTERIA 审中-公开
Title translation: 人工乳寡糖在工程菌中的生物合成公开(公告)号:WO2012112777A3
公开(公告)日:2012-11-08
申请号:PCT/US2012025450
申请日:2012-02-16
Applicant: GLYCOSYN LLC , MERIGHI MASSIMO , MCCOY JOHN M , HEIDTMAN MATTHEW IAN
Inventor: MERIGHI MASSIMO , MCCOY JOHN M , HEIDTMAN MATTHEW IAN
CPC classification number: C12N15/70 , C07H3/06 , C07H13/04 , C12N9/00 , C12N9/1051 , C12N9/2471 , C12P19/00 , C12P19/18 , C12P19/26 , Y02P20/52
Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
Abstract translation: 本发明提供了用于改造细菌生产岩藻糖基化寡糖的组合物和方法,以及其在预防或治疗感染中的用途。
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2.BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN ENGINEERED BACTERIA 审中-公开
Title translation: 人工细菌中人乳酸低聚糖的生物化学公开(公告)号:WO2012112777A2
公开(公告)日:2012-08-23
申请号:PCT/US2012/025450
申请日:2012-02-16
Applicant: GLYCOSYN LLC , MERIGHI, Massimo , MCCOY, John, M. , HEIDTMAN, Matthew, Ian
Inventor: MERIGHI, Massimo , MCCOY, John, M. , HEIDTMAN, Matthew, Ian
CPC classification number: C12N15/70 , C07H3/06 , C07H13/04 , C12N9/00 , C12N9/1051 , C12N9/2471 , C12P19/00 , C12P19/18 , C12P19/26 , Y02P20/52
Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
Abstract translation: 本发明提供用于工程细菌生产岩藻糖基化寡糖的组合物和方法及其在预防或治疗感染中的用途。
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3.THE USE OF PURIFIED 2'-FUCOSYLLACTOSE, 3-FUCOSYLLACTOSE AND LACTODIFUCOTETRAOSE AS PREBIOTICS 审中-公开
Title translation: 纯化的2'-纤维脂肪酸,3-FUCOSLLACTOSE和LACTODIFOCOTETRAOSE作为预处理的使用公开(公告)号:WO2012158517A1
公开(公告)日:2012-11-22
申请号:PCT/US2012/037522
申请日:2012-05-11
Applicant: GLYCOSYN LLC , TRUSTEES OF BOSTON COLLEGE , NEWBURG, David, S. , MCCOY, John, M. , MERIGHI, Massimo , HEIDTMAN, Matthew, Ian , YU, Zhuoteng
Inventor: NEWBURG, David, S. , MCCOY, John, M. , MERIGHI, Massimo , HEIDTMAN, Matthew, Ian , YU, Zhuoteng
IPC: C07H3/06 , A61K31/702 , A23L1/30 , A61P1/14
CPC classification number: A61K31/702 , A23L2/52 , A23L33/10 , A23L33/21 , A23L33/28 , A23L33/40 , A23V2002/00 , C07H3/06 , Y02A50/473 , Y02A50/481
Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
Abstract translation: 本发明提供了利用合成人乳寡糖作为益生元的组合物和方法。
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