公开(公告)号：WO2007107792A1

公开(公告)日：2007-09-27

申请号：PCT/GB2007/050138

申请日：2007-03-21

申请人： THE UNIVERSITY OF LINCOLN ,  WHITE, Peter, Cyril ,  HJORTKJÆR, Jakob, Howie

发明人： WHITE, Peter, Cyril ,  HJORTKJÆR, Jakob, Howie

IPC分类号： B01J13/00 ,  C22B11/00 ,  B22F1/00 ,  B22F9/24

CPC分类号： B01J13/0043 ,  B22F1/0022 ,  B22F9/24 ,  B82Y15/00 ,  B82Y30/00 ,  C22B11/04

摘要： A method is described for producing highly stable silver colloidal solu- tions by reducing silver nitrate with lithium citrate. In the method, the main steps consist of: (a) heating a first quantity of water to a first predetermined temperature; (b) adding a second quantity of silver nitrate to the water; (c) heat- ing the mixture to a second predetermined temperature; (d) adding a third quan- tity of an aqueous lithium citrate solution to the mixture; (e) maintaining the mix- ture at the second predetermined temperature for a predetermined time; and (f) cooling the mixture. The mixing process is accompanied by constant stirring. The colloid exhibits high light-scattering properties and intense SERS or SERRS spectra with low background fluorescence levels and a long shelf life, making it particularly suitable for Raman spectroscopy.

摘要翻译： 描述了通过用柠檬酸锂还原硝酸银来生产高度稳定的银胶体溶液的方法。 在该方法中，主要步骤包括：（a）将第一量的水加热至第一预定温度; （b）向水中加入第二量的硝酸银; （c）将混合物加热至第二预定温度; （d）向混合物中加入第三量的柠檬酸锂水溶液; （e）将混合物保持在第二预定温度一段预定时间; 和（f）冷却混合物。 混合过程伴随着持续搅拌。 胶体表现出高的光散射性能和强烈的SERS或SERRS光谱，具有低背景荧光水平和长保质期，使其特别适用于拉曼光谱。