公开(公告)号：WO2021127202A1

公开(公告)日：2021-06-24

申请号：PCT/US2020/065645

申请日：2020-12-17

Applicant: INARI MEDICAL, INC.

Inventor： THRESS, John Coleman

IPC: A61B17/221 ,  A61B17/22 ,  A61B17/3207 ,  A61B17/34 ,  A61F2/01 ,  A61F2/86 ,  A61B17/22031 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61B2017/22035

Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. In one embodiment, a system includes a coring element for coring and separating the clot material. The coring element can comprise a unitary structure having a first region, a second region, a third region, and a fourth region. The first region is adjacent to a proximal portion of the unitary structure and includes a first mouth configured to core and separate the clot material. The second region is distal of the first region, generally tubular, and includes a first plurality of interconnected struts. The third region is distal of the second region and includes a second mouth configured to core and separate the vascular thrombus. The fourth region is distal of the third region, generally tubular, and includes a second plurality of interconnected struts.

公开(公告)号：WO2021076954A1

公开(公告)日：2021-04-22

申请号：PCT/US2020/056067

申请日：2020-10-16

Applicant: INARI MEDICAL, INC.

Inventor： DINH, James Quang

IPC: A61B17/14 ,  A61B17/22 ,  A61B17/32 ,  A61F2/01 ,  A61M25/01 ,  A61M25/08

Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A device in accordance with embodiments of the present technology can include, for example, a plurality of interconnected struts forming a unitary structure having a proximal portion and a distal portion. The struts can form a plurality of first cells in the proximal portion and a plurality of second cells, smaller than the first cells, in the distal portion. The device can be pulled against clot material within a blood vessel to engage, disrupt, and/or capture the clot material.

公开(公告)号：WO2022103848A1

公开(公告)日：2022-05-19

申请号：PCT/US2021/058793

申请日：2021-11-10

Applicant: INARI MEDICAL, INC. ,  MACIAS, Jacqueline

Inventor： ENRIGHT, Paige Elizabeth ,  TU, Thomas M.

IPC: A61B17/03 ,  A61B17/04

Abstract: Disclosed herein are devices, systems, and methods for adjustably tensioning sutures, such as sutures used to close a catheter access site of a human patient. In some embodiments, a suture tensioning device includes a housing and an actuation member slidably coupled to the housing. The housing can include a first through-hole and a second through-hole at least partially aligned along an axis. The actuation member can include a third-through-hole. The suture tensioning device can further include a biasing member operably coupled between the actuation member and the housing. The biasing member can bias the actuation member to a first position in which the third through-hole is offset from the axis. The actuation member is movable to a second position in which the third through-hole is at least partially aligned with the first and second through-holes along the axis.

公开(公告)号：WO2020036809A1

公开(公告)日：2020-02-20

申请号：PCT/US2019/045794

申请日：2019-08-08

Applicant: INARI MEDICAL, INC.

Inventor： MERRITT, Ben ,  MACIAS, Jaqueline ,  STRAUSS, Brian Michael ,  TU, Thomas

IPC: A61B17/22 ,  A61B17/221 ,  A61B17/3207 ,  A61M25/02 ,  A61M25/08 ,  A61M25/09

Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

公开(公告)号：WO2019050765A1

公开(公告)日：2019-03-14

申请号：PCT/US2018/048786

申请日：2018-08-30

Applicant: INARI MEDICAL, INC.

Inventor： MERRITT, Benjamin, E. ,  THRESS, John, C. ,  LUBOCK, Paul

IPC: A61M39/06

Abstract: Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

公开(公告)号：WO2022032173A1

公开(公告)日：2022-02-10

申请号：PCT/US2021/045072

申请日：2021-08-06

Applicant: INARI MEDICAL, INC. ,  RUGGLES, Kendall Anne ,  MERRITT, Benjamin Edward ,  STRAUSS, Brian Michael

Inventor： THRESS, John Coleman ,  HUNTER, Evan Stuart ,  ZIKRY, Christopher Andrew

IPC: A61M5/32 ,  A61M5/315 ,  A61B17/22 ,  A61B2017/22079 ,  A61M1/67 ,  A61M1/84 ,  A61M2205/584

Abstract: Automatically-locking syringes are disclosed herein. A syringe in accordance with embodiments of the present technology can include (i) a barrel, (ii) a plunger slidably positioned within the barrel, and (iii) a lock plate coupled to the barrel. The plunger also extends through an opening in the lock plate, and a biasing member is configured to bias the lock plate to a locking position. When the plunger is moved from a depressed position to a withdrawn position, the lock feature engages the lock plate to drive the lock plate away from the locking position to thereby permit the lock feature to pass through the opening in the lock plate. After the lock feature passes through the opening, the biasing member drives the lock plate to the locking position to inhibit movement of the plunger from the withdrawn position to the depressed position.

公开(公告)号：WO2017106877A1

公开(公告)日：2017-06-22

申请号：PCT/US2016/067628

申请日：2016-12-19

Applicant: INARI MEDICAL, INC.

Inventor： QUICK, Richard ,  COX, Brian, J.

IPC: A61M25/00

CPC classification number: A61M25/0045 ,  A61M2025/0059

Abstract: Catheter shafts and associated devices, systems, and methods are disclosed herein, A representative catheter in accordance with an embodiment of the disclosure includes a generally tubular outer structure and an inner structure surrounded by the outer structure. The inner structure surrounds a catheter lumen. The inner structure includes over-lapping edges such that, when the catheter is bent along its longitudinal axis, the over-lapping edges move relative to one another.

Abstract translation: 本文公开了导管轴和相关装置，系统和方法。根据本公开的实施例的代表性导管包括大致管状的外部结构和由外部结构围绕的内部结构。 内部结构围绕导管内腔。 内部结构包括重叠边缘，使得当导管沿其纵向轴线弯曲时，重叠边缘相对于彼此移动。

公开(公告)号：WO2017070702A1

公开(公告)日：2017-04-27

申请号：PCT/US2016/058536

申请日：2016-10-24

Applicant: INARI MEDICAL, INC.

Inventor： MARCHAND, Phil ,  THRESS, John C. ,  LOUW, Jacob F. ,  COX, Brian J. ,  QUICK, Richard

IPC: A61B17/221

CPC classification number: A61B17/221 ,  A61B17/320725 ,  A61B17/3415 ,  A61B2017/22094 ,  A61B2017/2212

Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

Abstract translation: 本文公开了用于从患者身体的血管中去除血栓的系统和方法。 该方法可以包括：提供血栓抽取装置，该血栓抽取装置包括由单一开窗结构形成的近侧自膨胀构件，由网状细丝网状结构形成的远侧基本圆柱形部分以及连接至远侧端部的内轴部件， 网状细丝网结构; 推进限制血栓提取装置的导管通过血管血栓，展开血栓提取; 缩回血栓提取装置以从血管壁分离一部分血栓并捕获网状细丝网状结构内的血栓部分; 并从体内抽出血栓提取装置以从患者体内除去血栓。

公开(公告)号：WO2022109034A1

公开(公告)日：2022-05-27

申请号：PCT/US2021/059735

申请日：2021-11-17

Applicant: INARI MEDICAL, INC.

Inventor： DOLENDO, Edward Enriquez ,  BRODT, Thomas Robert ,  TU, Thomas M.

IPC: A61M25/00

Abstract: Disclosed herein are clot removal systems including steerable catheters, and associated systems and methods. In some embodiments, a clot removal system includes (i) an aspiration catheter having a proximal region and a distal region and (ii) a handle coupled to the proximal region of the catheter and having an actuator. The distal region of the catheter can include a deflectable member, and the clot removal system can include a pull wire extending between the actuator and the deflectable member. Actuation of the actuator is configured to pull the pull wire to deflect the deflectable member to deflect the distal region relative to the proximal region. The deflection can facilitate steering of the catheter to hard-to-reach (e.g., tortuous) portions of the anatomy of a patient.

公开(公告)号：WO2022109021A1

公开(公告)日：2022-05-27

申请号：PCT/US2021/059718

申请日：2021-11-17

Applicant: INARI MEDICAL, INC.

Inventor： DOLENDO, Edward Enriquez ,  BRODT, Thomas Robert ,  TU, Thomas M.

IPC: A61M25/00 ,  A61B17/22

Abstract: Disclosed herein are aspiration guide catheters having a pre-shaped distal portion configured to deflect away from a longitudinal axis of the catheter, and associated systems and methods. In some embodiments, an aspiration guide catheter includes an inner liner defining a lumen and having a proximal region and a distal region. The catheter further includes a braid of wires over the inner liner, and a wire coiled around the braid over at least a portion of the distal region of the inner liner. At least a portion of the braid over the distal region of the inner liner is configured to deflect away from a longitudinal axis of the proximal region. The catheter can further include an outer sheath over the braid, the wire, and the inner liner.