公开(公告)号：WO2013124618A1

公开(公告)日：2013-08-29

申请号：PCT/GB2013/050263

申请日：2013-02-05

Applicant: INNOVATA BIOMED LIMITED

Inventor： PARKES, Philip Carl

IPC: A61M15/00

CPC classification number: A61M15/0003 ,  A61M15/0006 ,  A61M15/0065 ,  A61M2202/064

Abstract: A medicament delivery device (1) comprises a metering member (25) mounted for rotation adjacent a reservoir (22) containing a bulk quantity of medicament. The metering member (25) is adapted when at a filling position to volumetrically meter a desired dose of medicament from the reservoir (22). By rotation of the metering member (25) in a first sense said dose is transferred to a dispensing position at which the dose can be dispensed from the device (1). The metering member (25) and/or a component (90) to which the metering member (25) is operably linked is provided with formations (95) effective to prevent reverse rotation of the metering member (25) from the filling position.

Abstract translation: 药物输送装置（1）包括计量构件（25），该计量构件（25）安装成用于围绕容纳大量药物的贮存器（22）旋转。 计量构件（25）适于当在填充位置上容积地计量来自储存器（22）的期望剂量的药物时。 通过第一意义上的计量构件（25）的旋转，所述剂量被转移到可以从装置（1）分配剂量的分配位置。 计量构件（25）和/或与计量构件（25）可操作地连接的部件（90）设置有有效地防止计量构件（25）从填充位置反向旋转的结构（95）。

公开(公告)号：WO2013110927A1

公开(公告)日：2013-08-01

申请号：PCT/GB2013/050101

申请日：2013-01-17

Applicant: INNOVATA BIOMED LIMITED

Inventor： PARKES, Philip Carl

IPC: A61M15/00 ,  G06M1/24

CPC classification number: A61M15/0081 ,  A61M15/00 ,  A61M15/0003 ,  A61M15/0065 ,  A61M15/007 ,  A61M15/0078 ,  A61M2202/0007 ,  A61M2202/064 ,  A61M2205/0216 ,  A61M2205/273 ,  G06M1/246 ,  G06M3/02

Abstract: A medicament delivery device (1) comprises an actuation mechanism by successive operation of which a predetermined number of unit doses of medicament can be dispensed. The device includes a locking mechanism for preventing further operation of the actuation mechanism after dispensing of said predetermined number of unit doses. The locking mechanism comprises a resilient member (51), a formation (18) with which the resilient member (51) is engageable to disable operation of the actuation mechanism, and a barrier member (20) that prevents engagement of the resilient member (51) and the formation (18) until said predetermined number of unit doses has been dispensed. The device (1) may be a dry powder inhaler.

Abstract translation: 药物输送装置（1）包括通过连续操作的致动机构，可以分配预定数量的单位剂量的药物。 该装置包括锁定机构，用于在分配所述预定数量的单位剂量之后防止致动机构的进一步操作。 锁定机构包括弹性构件（51），与弹性构件（51）可接合以禁止致动机构的操作的构件（18）以及防止弹性构件（51）的接合的阻挡构件（20） ）和形成（18），直到已经分配所述预定数量的单位剂量。 装置（1）可以是干粉吸入器。

公开(公告)号：WO2005102430A1

公开(公告)日：2005-11-03

申请号：PCT/GB2005/001572

申请日：2005-04-22

Applicant: INNOVATA BIOMED LIMITED ,  PARKES, Philip, Carl

Inventor： PARKES, Philip, Carl

IPC: A61M15/00

CPC classification number: G06M1/246 ,  A61M15/0065 ,  A61M15/0078 ,  A61M2202/064 ,  G06M1/04

Abstract: A dose counter mechanism is suitable for use with a medicament delivery device. The dose counter mechanism comprises a rollable tape (20) provided with indicia (22), a tape housing (10) and a tape collector spool (40). The tape housing comprises a tape dispenser housing (14) within which, in use, a roll (24) of the tape is inserted and a tape collector spool housing (16) within which, in use, the tape collector spool is mounted. The tape dispenser housing and the tape collector spool housing are connected by a tape display area (15).

Abstract translation: 剂量计数机构适用于药物输送装置。 剂量计数机构包括设置有标记（22）的可卷绕带（20），带壳（10）和带收集器卷轴（40）。 胶带外壳包括胶带分配器壳体（14），在使用中，胶带分配器壳体（14）在其中插入带的辊（24）和带收集器卷轴壳体（16），在使用中，胶带收集器卷轴安装在该收集器卷轴壳体内。 带分配器壳体和收集卷轴壳体通过带显示区域（15）连接。

公开(公告)号：WO2004103446A1

公开(公告)日：2004-12-02

申请号：PCT/GB2004/002234

申请日：2004-05-24

Applicant: INNOVATA BIOMED LIMITED ,  GORDON, James

Inventor： GORDON, James

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0036 ,  A61M15/0051

Abstract: Receptacle and delivery system for drugs delivered by powder inhalation and a method related thereto which provides improved entrainment, deagglomeration and/or aerosolisation of the powder. The receptacle (1) for holding a medicament comprises a cavity provided with a raised ridge (6, 22) which is adapted so that, in use, the airflow (in particular the inlet air or flushing air within the receptacle) is split into two substantially equal parts, e.g. providing first and second reservoirs.

Abstract translation: 通过粉末吸入输送的药物的插管和递送系统及其相关方法，其提供粉末的改进的夹带，解聚和/或雾化。 用于保持药物的容器（1）包括设置有凸脊（6,22）的腔，其适于使得在使用中，空气流（特别是容器内的入口空气或冲洗空气）被分成两部分 基本相等的部分，例如 提供第一和第二储层。

公开(公告)号：WO2009087407A1

公开(公告)日：2009-07-16

申请号：PCT/GB2009/000077

申请日：2009-01-12

Applicant: INNOVATA BIOMED LIMITED ,  BRIANT, John, Philip ,  MCDERMENT, Iain, Grierson ,  MARTYN, Glen, Patrick

Inventor： BRIANT, John, Philip ,  MCDERMENT, Iain, Grierson ,  MARTYN, Glen, Patrick

IPC: A61M15/00

CPC classification number: A61M15/0065 ,  A61M15/0003 ,  A61M2202/064

Abstract: A dry powder inhaler comprises at least one medicament reservoir containing a bulk quantity of a powdered medicament, and a metering mechanism by which unit doses of said medicament can be dispensed from the medicament reservoir for inhalation by a user of the inhaler. The at least one medicament reservoir is formed in polyester material. Penetration of moisture through the walls of the medicament reservoir is considerably reduced.

Abstract translation: 干粉吸入器包括至少一个含有大量粉末药物的药物储存器，以及计量机构，通过该计量机构可以从药剂容器分配单位剂量的所述药物以供吸入器的使用者吸入。 所述至少一个药剂容器在聚酯材料中形成。 通过药物储存器的壁渗透水分显着减少。

公开(公告)号：WO2005102429A1

公开(公告)日：2005-11-03

申请号：PCT/GB2005/001538

申请日：2005-04-21

Applicant: INNOVATA BIOMED LIMITED ,  PENG, Weidong ,  TOWNSEND, Christopher, Andrew

Inventor： PENG, Weidong ,  TOWNSEND, Christopher, Andrew

IPC: A61M15/00

CPC classification number: A61M15/0065 ,  A61M15/0003 ,  A61M2202/064 ,  A61M2206/14 ,  A61M2206/16

Abstract: A dry powder inhaler comprises an airway (1) along which, in use, air is drawn from an upstream, inlet end (2) to a downstream, outlet end (3). The airway (1) includes a medicament presentation region (4) at which, in use, a dose of medicament is presented to the airway (1), a primary air inlet (10), and a barrel (5) extending from the medicament presentation region (4) to the outlet end (3) of the airway (1). The inlet end of the barrel (5) is of reduced internal dimension relative to the medicament presentation region (4) and relative to the outlet end of the barrel (5), such that the inlet end of the barrel (5) constitutes a constriction of the airway (1). At least one secondary air inlet (11) is disposed such that, in use, air enters the airway (1) from the secondary air inlet (11) in a direction that is substantially orthogonal to the direction of flow of air along said barrel (5).

Abstract translation: 干粉吸入器包括气道（1），在使用中，空气从上游入口端（2）抽吸到下游出口端（3）。 气道（1）包括药物呈现区域（4），在使用中，一定剂量的药物呈现给气道（1），主空气入口（10）和从药物 呈现区域（4）到气道（1）的出口端（3）。 筒体（5）的入口端相对于药物呈现区域（4）相对于筒体（5）的出口端具有减小的内部尺寸，使得筒体（5）的入口端构成收缩部 的气道（1）。 设置至少一个二次空气入口（11），使得在使用中，空气沿着沿着所述筒的空气流动方向基本正交的方向从二次空气入口（11）进入气道（1） 5）。

公开(公告)号：WO2005030305A1

公开(公告)日：2005-04-07

申请号：PCT/GB2004/004082

申请日：2004-09-27

Applicant: INNOVATA BIOMED LIMITED ,  BRAITHWAITE, Philip

Inventor： BRAITHWAITE, Philip

IPC: A61M15/00

CPC classification number: B67B7/40 ,  A61M15/0003 ,  A61M15/0031 ,  A61M15/0036 ,  A61M15/0045 ,  A61M15/0051 ,  A61M2202/064 ,  B65B69/0041

Abstract: A system for delivery of a medicament comprises a medicament container in the form of a reservoir (31) with a frangible closure (35), and a plurality of opening means (310). At least one of the opening means (310) is capable of displacing at least a portion of the frangible closure (35) outwardly. The system is particularly suited to incorporation into a dry powder inhaler.

Abstract translation: 用于递送药物的系统包括具有易碎封闭件（35）的储存器（31）形式的药物容器和多个开启装置（310）。 开口装置（310）中的至少一个能够使易碎封闭件（35）的至少一部分向外移位。 该系统特别适用于掺入干粉吸入器。

公开(公告)号：WO2003045483A3

公开(公告)日：2003-06-05

申请号：PCT/GB2002/005272

申请日：2002-11-22

Applicant: INNOVATA BIOMED LIMITED ,  BRAITHWAITE, Philip

Inventor： BRAITHWAITE, Philip

IPC: A61M15/00

Abstract: There is described a medicament delivery assembly which comprises mouthpiece (8) provided with an air amplifier (12) and a primer source (1,4), wherein the mouthpiece (8) and the air amplifier (12) are each is connected to the primer source (1,4) via an actuatable valve (6); the air amplifier (6) is also provided with a medicament extraction tube such that when the actuatable valve (6) is opened then the primer source (4) is activated and causes air to flow to the air amplifier (4). There is also described a method of administering a medicament which comprises the use of such a medicament delivery assembly.

公开(公告)号：WO2002098495A1

公开(公告)日：2002-12-12

申请号：PCT/GB2002/002301

申请日：2002-06-05

Applicant: INNOVATA BIOMED LIMITED ,  BRAITHWAITE, Philip

Inventor： BRAITHWAITE, Philip

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0036 ,  A61M15/0048 ,  A61M15/0051 ,  A61M15/0061 ,  A61M2202/064

Abstract: There is described a unit dosage powder receptacle which receptacle is provided with a frangible sealing member characterised in that the receptacle is provided with means to enable the frangible sealing member to be ruptured by inserting a powder flow channel through the sealing member such that the sealing member ruptures in a direction away from the powder. There is also described a rupturing member adapted for rupturing such a unit dosage powder receptacle and also a powder delivery device comparing a unit dosage powder receptacle and a method of treatment related thereto.

Abstract translation: 描述了一种单位剂量粉末容器，其容器设置有易碎的密封构件，其特征在于，容器设置有使脆性密封构件能够通过将粉末流动通道插入穿过密封构件而破裂的装置，使得密封构件 在远离粉末的方向上破裂。 还描述了一种破裂构件，其适于破裂这种单位剂量粉末容器以及比较单位剂量粉末容器的粉末输送装置和与之相关的处理方法。

公开(公告)号：WO2007042822A3

公开(公告)日：2007-04-19

申请号：PCT/GB2006/003803

申请日：2006-10-12

Applicant: INNOVATA BIOMED LIMITED ,  LUCKING, Samuel, William ,  MARTYN, Glen, Patrick

Inventor： LUCKING, Samuel, William ,  MARTYN, Glen, Patrick

IPC: A61M15/00

Abstract: An inhaler comprising a first and second body member, the first body member and the second body member fitting closely together to form an inhaler body, and an outlet. The first body member includes a medicament chamber containing a unit dose of powdered medicament and a foil that closes the medicament chamber extending outwardly of the inhaler body to be grasped and withdrawn, thereby releasing the powdered medicament from the medicament chamber. The second body member includes a medicament collection well in which the released medicament is collected. The medicament collection well forms part of an airway communicating with the outlet, allowing inhalation air to entrain medicament in the medicament collection well. In another embodiment, the inhaler body includes a dispersion chamber. There is also disclosed a dry powder for inhalation comprising a desiccant and a bioactive agent, and a method of delivering a medicament to a patient.