PROCESS FOR MAKING MICRONEEDLES, MICRONEEDLE ARRAYS, MASTERS, AND REPLICATION TOOLS
    3.
    发明申请
    PROCESS FOR MAKING MICRONEEDLES, MICRONEEDLE ARRAYS, MASTERS, AND REPLICATION TOOLS 审中-公开
    制作麦克风,麦克风阵列,主机和复印工具的方法

    公开(公告)号:WO2007112309A3

    公开(公告)日:2007-12-27

    申请号:PCT/US2007064789

    申请日:2007-03-23

    Abstract: A process for making a microneedle array master comprises: (a) providing a photoreactive composition, the photoreactive composition comprising: (1) at least one reactive species that is capable of undergoing an acid- or radical-initiated chemical reaction, and (2) at least one multiphoton photoinitiator system; and (b) imagewise exposing at least a portion of the composition to light sufficient to cause simultaneous absorption of at least two photons, thereby inducing at least one acid- or radical-initiated chemical reaction where the composition is exposed to the light, the imagewise exposing being carried out in a pattern that is effective to define at least the surface of a plurality of microneedles. The microneedles may be solid and the outer surface of the microneedles may be characterized by at least one concave area. The master may be used to fabricate a tool for replication.

    Abstract translation: 制备微针阵列母版的方法包括:(a)提供光反应性组合物,所述光反应性组合物包含:(1)能够经历酸或自由基引发的化学反应的至少一种反应性物质,和(2) 至少一种多光子光引发剂体系; 和(b)将组合物的至少一部分成像曝光至足以引起同时吸收至少两个光子的光,从而诱导至少一种酸或自由基引发的化学反应,其中组合物暴露于光,成像 以能有效地限定多个微针的表面的图案进行曝光。 微针可以是固体,并且微针的外表面可以由至少一个凹入区域表征。 主人可能用于制作复制工具。

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