公开(公告)号：WO1994015609A1

公开(公告)日：1994-07-21

申请号：PCT/KR1993000127

申请日：1993-12-31

Applicant: SUNKYONG INDUSTRIES CO., LTD. ,  MIN, Dong, Son ,  UM, Kee, An ,  KIM, Yong, Soo ,  PARK, Pyeong, Uk ,  KIM, Key, Hyup ,  YANG, Ho, Seung ,  JEONG, Hey, Soon ,  PARK, Mi, Young

Inventor： SUNKYONG INDUSTRIES CO., LTD.

IPC: A61K31/54

CPC classification number: A61K9/7061 ,  A61K31/54 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/18 ,  A61K47/20

Abstract: The present invention is directed to pharmaceutical compositions improving percutaneous absorbability by absorption assistants, which remarkably increase permeation and dissolution of piroxicam, and penetration enhancers. A further surprising feature of the present invention resides in the fact that absorption assistant which assists penetration enhancer is able to include the active substance excessively in adhesive matrix as solvent of the active substance.

Abstract translation: 本发明涉及通过吸收助剂改善经皮吸收性的药物组合物，其显着增加了炎痛喜珠菌的渗透和溶解以及渗透促进剂。 本发明的另一个令人惊奇的特征在于，辅助渗透促进剂的吸收助剂能够将活性物质过量地包含在作为活性物质的溶剂的粘合剂基质中。

公开(公告)号：WO1995023138A1

公开(公告)日：1995-08-31

申请号：PCT/KR1994000102

申请日：1994-07-29

Applicant: SUNKYONG INDUSTRIES CO., LTD. ,  KIM, Dae-Kee ,  GAM, Jongsik ,  KIM, Ganghyeok ,  KIM, Young-Woo ,  LEE, Namkyu ,  LIM, Jinsoo ,  KIM, Hun-Taek ,  KIM, Key, Hyup

Inventor： SUNKYONG INDUSTRIES CO., LTD.

IPC: C07D239/545

CPC classification number: C07D239/56 ,  C07D239/54

Abstract: The present invention relates to novel pyrimidine acyclonucleoside derivatives represented by general formula (I), antiviral agents containing the derivatives as the active ingredients and processes of preparation therefor. In formula (I), R represents ethyl group or isopropyl group; R represents phenylselenenyl group, optionally substituted with one or more suitable substituents selected from C1-C3 alkyl group or halogen atom; R represents hydrogen atom, C1-C3 alkyl group, C1-C3 hydroxyalkyl group, acyloxyalkyl group, or phenyl group that is optionally substituted with one or more suitable substituents selected from C1-C3 alkyl group, C1-C3 alkoxy group or halogen atom; X represents oxygen atom or sulfur atom; and Y represents oxygen atom or methylene; with the proviso that R does not represent ethyl group when R represents phenylselenenyl group, R represents methyl group, and X and Y represent oxygen atom.

Abstract translation: 本发明涉及由通式（I）表示的新型嘧啶阿昔洛韦衍生物，含有该衍生物作为活性成分的抗病毒剂及其制备方法。 在式（I）中，R 1表示乙基或异丙基; R 2表示苯基硒基，任选被一个或多个选自C 1 -C 3烷基或卤素原子的合适取代基取代; R 3表示氢原子，C 1 -C 3烷基，C 1 -C 3羟基烷基，酰氧基烷基或任选被一个或多个选自C 1 -C 3烷基，C 1 -C 3烷氧基或 卤素原子; X表示氧原子或硫原子; Y代表氧原子或亚甲基; 条件是当R 2表示苯基硒基时，R 1不表示乙基，R 3表示甲基，X和Y表示氧原子。

公开(公告)号：WO2008105618A1

公开(公告)日：2008-09-04

申请号：PCT/KR2008/001102

申请日：2008-02-26

Applicant: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY ,  KIM, Gyung Soo ,  SHIN, Myung-Kyo ,  KIM, Yong Jin ,  OH, Kyeong Keun ,  KIM, JUN SEOK ,  RYU, Hyun Jin ,  KIM, Key Hyup

Inventor： KIM, Gyung Soo ,  SHIN, Myung-Kyo ,  KIM, Yong Jin ,  OH, Kyeong Keun ,  KIM, JUN SEOK ,  RYU, Hyun Jin ,  KIM, Key Hyup

IPC: C12P7/06

CPC classification number: C12P7/06 ,  C12P7/04 ,  C12P7/16 ,  C12P7/28 ,  Y02E50/10 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to a method of producing biofuel, more specifically a method of producing biofuel comprising the steps of generating monosugars from marine algae, or from polysaccharides extracted from marine algae by treating the marine algae or the polysaccharides with a hydrolytic enzyme and/or a hydrolytic catalyst; and fermenting the monosugars using a microorganism to produce biofuel. The method of producing biofuel of the present invention solve the problem of raw material suppliance since it uses marine algae as a raw material for biomass, and reduce the production costs by excluding lignin eliminating process that has been required by the conventional method using wood-based raw materials, resulting in economic and environmental advantages.

Abstract translation: 本发明涉及一种生产生物燃料的方法，更具体地说是一种生产生物燃料的方法，包括以下步骤：从海藻中产生单糖，或从海藻中提取的多糖，用水解酶处理海藻或多糖，和/或 水解催化剂; 并使用微生物发酵单糖以生产生物燃料。 本发明生产生物燃料的方法解决了由于采用海藻作为生物质原料的原料消耗问题，并且通过排除木质素消除过程来降低生产成本 原料，造成经济环境优势。

公开(公告)号：WO1992016539A1

公开(公告)日：1992-10-01

申请号：PCT/KR1991000036

申请日：1991-12-30

Applicant: SUNKYONG INDUSTRIES LTD. ,  KIM, Dae-Kee ,  KIM, Ganghyeok ,  GAM, Jongsik ,  CHO, Yong, Baik ,  KIM, Hun, Taek ,  TAI, Joo, Ho ,  KIM, Key, Hyup

Inventor： SUNKYONG INDUSTRIES LTD.

IPC: C07F15/00

CPC classification number: C07F15/0093

Abstract: Disclosed herein are novel platinum(II) complexe having a potent anti-tumor activity which are represented by formula (1), wherein R1 and R2, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cycloalkane group together with the carbon atom attached thereto; two Xs jointly form a group represented by formula (a) or (b) wherein, R3 is a hydrogen atom or a methyl group; R4 and R5, which may be the same or different, are a hydrogen atom or a C1-4 alkyl group, respectively, or jointly form a cyclobutane together with the carbon thereto; and the absolute configurations at the respective chiral centers in the 4,5-bis(aminomethyl)-1,3-dioxolane moiety are (4R, 5R) or (4S, 5S); processes for preparing the same; and their use for treating animal or human cancer. Further, disclosed herein are novel intermediates useful for the preparation of the platinum(II) complexes and processes for preparing said intermediates.

Abstract translation: 本文公开了具有由式（1）表示的有效抗肿瘤活性的新型铂（II）络合物，其中可以相同或不同的R 1和R 2为氢原子或C 1-4烷基， 或者与连接的碳原子一起共同形成环烷烃基; 两个X共同形成由式（a）或（b）表示的基团，其中R3是氢原子或甲基; R4和R5可以相同或不同，分别为氢原子或C1-4烷基，或与其一起共同形成环丁烷; 并且4,5-双（氨基甲基）-1,3-二氧戊环部分各手性中心的绝对构型为（4R，5R）或（4S，5S）; 制备方法 及其用于治疗动物或人类癌症的用途。 此外，本文公开了可用于制备铂（II）络合物的新中间体和用于制备所述中间体的方法。