公开(公告)号：WO0222773A3

公开(公告)日：2003-10-09

申请号：PCT/EP0110668

申请日：2001-09-14

Applicant: SHELL INT RESEARCH ,  CORCHO-SANCHEZ DIEGO ,  LERNER DAVID NICHOLAS ,  STEPHENSON RICHARD JOHN ,  WATKINSON ROBERT JAMES

Inventor： CORCHO-SANCHEZ DIEGO ,  LERNER DAVID NICHOLAS ,  STEPHENSON RICHARD JOHN ,  WATKINSON ROBERT JAMES

IPC: C02F3/10 ,  C12M1/12

CPC classification number: C12M29/04

Abstract: A bioreactor for microbial conversion of at least one conversion substrate, which comprises a treatment zone to accommodate when in use a solution of said at least one conversion substrate, a culture holding zone to accommodate when in use a microbial culture capable of metabolising said at least one conversion substrate, a source of primary growth substrate for the microbial culture, a first permeable membrane forming an interface between the treatment zone and the culture holding zone, and a second permeable membrane forming an interface between the source of primary growth substrate and the culture holding zone, the first permeable membrane being of a material which will allow passage of the at least one conversion substrate from the treatment zone to the culture holding zone whilst being impermeable to the microbial culture, the second permeable membrane being of a material permeable to the primary growth substrate but substantially impermeable to water; and a process of operating said bioreactor.

Abstract translation: 一种用于至少一种转化底物的微生物转化的生物反应器，其包含处理区，以在使用时适应所述至少一种转化底物的溶液，培养保持区，以在使用时适应能够代谢至少所述至少一种转化底物的微生物培养物 一个转化底物，用于微生物培养的一次生长底物源，形成处理区和培养保持区之间的界面的第一渗透膜，以及形成初级生长底物源和培养物之间的界面的第二渗透膜 所述第一渗透膜是允许所述至少一个转化基质从所述处理区通过所述培养保持区同时对所述微生物培养物不可渗透的材料，所述第二渗透膜是可透过的 初级生长基质，但基本上不透水; 以及操作所述生物反应器的过程。