公开(公告)号：WO2007025248A3

公开(公告)日：2007-03-01

申请号：PCT/US2006/033498

申请日：2006-08-24

Applicant: WYETH ,  MOSYAK, Lidia ,  RUSH III, Thomas Saltmarsh ,  ZHONG, Xiaotian ,  MCDONAGH, Thomas E. ,  GEORGIADIS, Katy E. ,  SUM, Phaik-Eng ,  LAVALLIE, Edward R. ,  COLLINS-RACIE, Lisa A. ,  CORCORAN, Christopher John ,  KUMAR, Ravindra ,  HEBERT, Tracy ,  OLLAND, Stephane Hubert ,  MACKIE, Stewart Andrews

Inventor： MOSYAK, Lidia ,  RUSH III, Thomas Saltmarsh ,  ZHONG, Xiaotian ,  MCDONAGH, Thomas E. ,  GEORGIADIS, Katy E. ,  SUM, Phaik-Eng ,  LAVALLIE, Edward R. ,  COLLINS-RACIE, Lisa A. ,  CORCORAN, Christopher John ,  KUMAR, Ravindra ,  HEBERT, Tracy ,  OLLAND, Stephane Hubert ,  MACKIE, Stewart Andrews

IPC: C12N9/64 ,  G06F19/00 ,  G01N23/20 ,  C30B7/00

Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.

公开(公告)号：WO2007025248B1

公开(公告)日：2007-10-11

申请号：PCT/US2006033498

申请日：2006-08-24

Applicant: WYETH CORP ,  MOSYAK LIDIA ,  RUSH III THOMAS SALTMARSH ,  ZHONG XIAOTIAN ,  MCDONAGH THOMAS E ,  GEORGIADIS KATY E ,  SUM PHAIK-ENG ,  LAVALLIE EDWARD R ,  COLLINS-RACIE LISA A ,  CORCORAN CHRISTOPHER JOHN ,  KUMAR RAVINDRA ,  HEBERT TRACY ,  OLLAND STEPHANE HUBERT ,  MACKIE STEWART ANDREWS

Inventor： MOSYAK LIDIA ,  RUSH III THOMAS SALTMARSH ,  ZHONG XIAOTIAN ,  MCDONAGH THOMAS E ,  GEORGIADIS KATY E ,  SUM PHAIK-ENG ,  LAVALLIE EDWARD R ,  COLLINS-RACIE LISA A ,  CORCORAN CHRISTOPHER JOHN ,  KUMAR RAVINDRA ,  HEBERT TRACY ,  OLLAND STEPHANE HUBERT ,  MACKIE STEWART ANDREWS

IPC: C12N9/64 ,  C30B7/00 ,  G01N23/20 ,  G06F19/00

CPC classification number: C12N9/6421 ,  C07K2299/00 ,  C30B7/00

Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.

公开(公告)号：WO2007025248A2

公开(公告)日：2007-03-01

申请号：PCT/US2006033498

申请日：2006-08-24

Applicant: WYETH CORP ,  MOSYAK LIDIA ,  RUSH III THOMAS SALTMARSH ,  ZHONG XIAOTIAN ,  MCDONAGH THOMAS E ,  GEORGIADIS KATY E ,  SUM PHAIK-ENG ,  LAVALLIE EDWARD R ,  COLLINS-RACIE LISA A ,  CORCORAN CHRISTOPHER JOHN ,  KUMAR RAVINDRA ,  HEBERT TRACY ,  OLLAND STEPHANE HUBERT ,  MACKIE STEWART ANDREWS

Inventor： MOSYAK LIDIA ,  RUSH III THOMAS SALTMARSH ,  ZHONG XIAOTIAN ,  MCDONAGH THOMAS E ,  GEORGIADIS KATY E ,  SUM PHAIK-ENG ,  LAVALLIE EDWARD R ,  COLLINS-RACIE LISA A ,  CORCORAN CHRISTOPHER JOHN ,  KUMAR RAVINDRA ,  HEBERT TRACY ,  OLLAND STEPHANE HUBERT ,  MACKIE STEWART ANDREWS

IPC: C07K14/43

CPC classification number: C12N9/6421 ,  C07K2299/00 ,  C30B7/00

Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.

Abstract translation: 本发明涉及聚集蛋白聚糖酶多肽和聚集蛋白聚糖酶多肽/配体复合物，聚集蛋白聚糖酶和聚集蛋白聚糖酶多肽/配体复合物的晶体以及相关方法和软件系统。