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1.发明申请
公开(公告)号：WO2008133731A2
公开(公告)日：2008-11-06
申请号：PCT/US2007085059
申请日：2007-11-19
发明人： WITHIAM MICHAEL C , MEHRA DEV K , CORNELIUS JOHN M
IPC分类号： A61K9/46 , A61K8/02 , A61K8/25 , A61K8/34 , A61K8/35 , A61K8/49 , A61K8/73 , A61K9/20 , A61Q11/00
CPC分类号： A61K8/02 , A61K8/0216 , A61K8/25 , A61K8/345 , A61K8/35 , A61K8/4913 , A61K8/732 , A61Q11/00
摘要： This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a silica material in combination with other common tablet components. Such a silica material must exhibit a sufficiently low surface area in order to boost the ability of the table to separate quickly when introduced into a user's mouth cavity. Such a tablet is dimensionally stable prior to use (low friability) and, when immersed in water the tablet disintegrates therein in less than about 60 seconds.
摘要翻译： 本发明涉及通过将二氧化硅材料与其它常用片剂组合物组合而提供快速崩解片剂的能力。 这样的二氧化硅材料必须表现出足够低的表面积，以便在引入使用者的口腔时提高桌子快速分离的能力。 这种片剂在使用前是尺寸稳定的（低脆性），并且当浸入水中时，片剂在小于约60秒内崩解。
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2.发明申请
公开(公告)号：WO2008082808A1
公开(公告)日：2008-07-10
申请号：PCT/US2007/085048
申请日：2007-11-19
IPC分类号： A61K9/20
CPC分类号： A61K45/06 , A61K8/19 , A61K8/345 , A61K8/731 , A61K8/732 , A61K8/8176 , A61K9/0056 , A61K9/2018 , A61K31/00 , A61Q11/00
摘要： This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a calcium carbonate material in combination with other common tablet components. Such a calcium carbonate material must exhibit a sufficiently low surface area in order to boost the ability of the tablet to separate quickly when introduced into a user's mouth cavity. Such a tablet is dimensionally stable prior to use (low friability) and, when immersed in water the tablet disintegrates therein in less than about 60 seconds.
摘要翻译： 本发明涉及通过将碳酸钙材料与其它普通片剂组合物组合而提供快速崩解片剂的能力。 这种碳酸钙材料必须表现出足够低的表面积，以便在引入使用者口腔时提高片剂快速分离的能力。 这种片剂在使用前是尺寸稳定的（低脆性），并且当浸入水中时，片剂在小于约60秒内崩解。
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公开(公告)号：WO2005110376A3
公开(公告)日：2006-06-15
申请号：PCT/US2005003538
申请日：2005-01-28
发明人： MEHRA DEV K , WITHIAM MICHAEL C , CORNELIUS JOHN M
CPC分类号： A61K9/2027 , A61K9/0056 , A61K9/2009 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K33/24
摘要： An orally-administered, rapidly disintegrating tablet is provided. The tablet comprises: a titanium dioxide; a super disintegrant; and a sugar alcohol. When immersed in water the tablet has a friability of less than about 2% and disintegrates in less than about 60 seconds.
摘要翻译： 提供口服的快速崩解片剂。 片剂包括：二氧化钛; 超级崩解剂 和糖醇。 当浸在水中时，片剂具有小于约2％的脆性，并在小于约60秒内分解。
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公开(公告)号：WO2005110346A1
公开(公告)日：2005-11-24
申请号：PCT/US2005/003508
申请日：2005-01-28
IPC分类号： A61K7/16
CPC分类号： A61K9/2009 , A61K8/19 , A61K9/0056 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61Q11/00
摘要： A rapidly disintegration oral care tablet is provided. The tablet comprises: a calcium phosphate; a super disintegrant; and a sugar alcohol. When immersed in water the tablet has a friability of less than about 2 % and disintegrates in less than about 60 seconds.
摘要翻译： 提供快速崩解的口腔护理片剂。 片剂包括：磷酸钙; 超级崩解剂 和糖醇。 当浸在水中时，片剂具有小于约2％的脆性，并在小于约60秒内分解。
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5.发明申请ENTERIC FILM COATING COMPOSITIONS, METHOD OF COATING THEREWITH, AND COATED FORMS 审中-公开电镀膜组合物，涂层方法和涂层形式
公开(公告)号：WO1996010995A1
公开(公告)日：1996-04-18
申请号：PCT/US1995012934
申请日：1995-10-06
申请人： BERWIND PHARMACEUTICAL SERVICES, INC. , MEHRA, Dev, K. , RAMIREDDY, Chittamuru , TANG, Li-Juan , PORTER, Stuart, C.
IPC分类号： A61K09/36
CPC分类号： A61K9/2813 , A61K9/284 , A61K9/2866
摘要： A non-toxic edible enteric film coating dry powder composition for use in making an aqueous enteric coating suspension which may be used in coating pharmaceutical tablets and the like comprises an enteric film forming polymer, a detackifier, a viscosity modifier, and an alkalizing/anti-coagulating agent. Advantageously, the inventive dry powder compositions may include a solid plasticizer, a lubricant, an anti-caking agent, a liquid plasticizer, and a pigment.
摘要翻译： 用于制备可用于包衣药片等的水性肠溶衣悬浮液的无毒可食性肠溶薄膜包衣干粉组合物包括肠溶成膜聚合物，防粘剂，粘度调节剂和碱化/抗 凝固剂。 有利地，本发明的干粉组合物可包括固体增塑剂，润滑剂，抗结块剂，液体增塑剂和颜料。
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6.发明申请
公开(公告)号：WO2008082810A1
公开(公告)日：2008-07-10
申请号：PCT/US2007/085050
申请日：2007-11-19
IPC分类号： A61K9/46
CPC分类号： A61K9/0056 , A61K9/2009 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K33/24
摘要： This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a titanium dioxide materia! in combination with other common tablet components Such a titanium dioxide material must exhibit a sufficiently low surface area in order to boost the ability of the tablet to separate quickly when introduced into a user's mouth cavity. Such a tablet is dimensionaily stable prior to use (low friability) and, when immersed in water the tablet disintegrates therein in less than about 60 seconds.
摘要翻译： 本发明涉及通过包含二氧化钛材料来提供快速崩解片剂的能力！ 与其它常见的片剂组分组合这样的二氧化钛材料必须表现出足够低的表面积，以便在引入使用者的口腔时提高片剂快速分离的能力。 这样的片剂在使用前具有维度上的稳定性（低脆性），并且当浸入水中时，片剂在小于约60秒内崩解。
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7.发明申请
公开(公告)号：WO2008082809A1
公开(公告)日：2008-07-10
申请号：PCT/US2007/085049
申请日：2007-11-19
CPC分类号： A61K8/19 , A61K9/0056 , A61K9/2009 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61Q11/00
摘要： This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a calcium phosphate material in combination with other common tablet components. Such a calcium phosphate material must exhibit a sufficiently low surface area in order to boost the ability of the table to separate quickly when introduced into a user's mouth cavity. Such a tablet is dimensionally stable prior to use (low friability) and, when immersed in water the tablet disintegrates therein in less than about 60 seconds.
摘要翻译： 本发明涉及通过将磷酸钙材料与其它普通片剂组合物组合而提供快速崩解片剂的能力。 这种磷酸钙材料必须表现出足够低的表面积，以便在引入使用者的口腔时提高桌子快速分离的能力。 这种片剂在使用前是尺寸稳定的（低脆性），并且当浸入水中时，片剂在小于约60秒内崩解。
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公开(公告)号：WO2008133731A3
公开(公告)日：2008-11-06
申请号：PCT/US2007/085059
申请日：2007-11-19
IPC分类号： A61K9/20
摘要： This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a silica material in combination with other common tablet components. Such a silica material must exhibit a sufficiently low surface area in order to boost the ability of the table to separate quickly when introduced into a user's mouth cavity. Such a tablet is dimensionally stable prior to use (low friability) and, when immersed in water the tablet disintegrates therein in less than about 60 seconds.
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公开(公告)号：WO2005110376A2
公开(公告)日：2005-11-24
申请号：PCT/US2005/003538
申请日：2005-01-28
IPC分类号： A61K9/20
CPC分类号： A61K9/2027 , A61K9/0056 , A61K9/2009 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K33/24
摘要： An orally-administered, rapidly disintegrating tablet is provided. The tablet comprises: a titanium dioxide; a super disintegrant; and a sugar alcohol. When immersed in water the tablet has a friability of less than about 2% and disintegrates in less than about 60 seconds.
摘要翻译： 提供口服的快速崩解片剂。 片剂包括：二氧化钛; 超级崩解剂 和糖醇。 当浸在水中时，片剂具有小于约2％的脆性，并在小于约60秒内分解。
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