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公开(公告)号：WO2022023759A2
公开(公告)日：2022-02-03
申请号：PCT/GB2021/051965
申请日：2021-07-29
发明人： BEVENIOU, Elina , BENNETT, Matt , KERR, Alex , TROTTER, Sam , HAYWARD, David
IPC分类号： B01D9/00 , A61K31/00 , A61K33/00 , B01D63/00 , A61K31/40 , A61K31/4184 , B01D2325/021 , B01D67/0055 , B01D69/02 , B01D69/04 , B01D71/022 , B01D9/0013 , B01D9/0054 , B01D9/0063 , B23B1/00
摘要： There is described a method of preparing solid particles of a compound, said method comprising controlling provision of a liquid phase, wherein said liquid phase comprises a solution of the compound, in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling the supersaturation of the liquid phase after it has passed through the membrane via the plurality of pores, to form solid particles of the compound. The method may comprise a continuous method.
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2.发明申请
公开(公告)号：WO2021240123A1
公开(公告)日：2021-12-02
申请号：PCT/GB2021/000062
申请日：2021-05-28
发明人： TROTTER, Sam , WILLIAMS, Bruce
IPC分类号： B01F3/08 , B01F5/04 , B01F5/06 , B01F23/41 , B01F23/413 , B01F25/3141 , B01F25/31421 , B01F25/4412 , B01F25/44165 , B01F25/4421 , B01F25/4422
摘要： Membrane Emulsification Apparatus with Refiner There is described a membrane emulsification apparatus for dispersing a first phase in a second phase, comprising: • a membrane defining a plurality of apertures connecting a first volume on a first side of the membrane to a second volume on a second, different, side of the membrane, the apparatus being arranged to receive a first phase containing a liquid in the first volume and to receive a second phase in the second volume the apparatus being adapted to generate an emulsion through egression of the first phase into the second phase via the plurality of apertures; • the apparatus also comprising a refiner (1) arranged to receive the emulsion from the membrane; and wherein said refiner comprises an inlet (4/5) and an outlet (5/4) wherein an opening (8) adapted to converge flow of the emulsion and to break up droplets of the emulsion into a refined emulsion is located between the inlet and the outlet.
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公开(公告)号：WO2013045918A1
公开(公告)日：2013-04-04
申请号：PCT/GB2012/052382
申请日：2012-09-26
发明人： HOLDICH, Richard
CPC分类号： B01F3/0807 , B01F3/0819 , B01F3/2215 , B01F3/2261 , B01F5/0485 , B01F11/0071 , B01F2215/0454
摘要： An apparatus for particle production, the apparatus comprising: a membrane (16) defining a plurality of apertures (36) and configured to receive a first liquid phase and to receive a second liquid phase via the plurality of apertures to form an emulsion; and a first reactor (24) configured to receive the emulsion from the membrane and to at least partially solidify droplets of the second liquid phase in the emulsion, the reactor comprising a plurality of connected reactor chambers (42).
摘要翻译： 一种用于颗粒生产的装置，所述装置包括：限定多个孔（36）并构造成接收第一液相并通过所述多个孔接收第二液相以形成乳液的膜（16） 以及第一反应器（24），其构造成从所述膜接收所述乳液并且至少部分地固化所述乳液中的所述第二液相的液滴，所述反应器包括多个连接的反应室（42）。
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公开(公告)号：WO2022018441A1
公开(公告)日：2022-01-27
申请号：PCT/GB2021/051887
申请日：2021-07-21
发明人： KERR, Alex , TROTTER, Sam , HAYWARD, David
IPC分类号： A61K9/127 , A61K9/51 , A61K31/485 , A61K31/704 , A61K31/7048 , A61K39/12 , A61P25/04 , A61P29/00 , A61P35/00
摘要： There is described a method of preparing lipid vesicles, said method comprising dispersing a first liquid phase in a second liquid phase; wherein said first liquid phase comprises a lipid phase and said second liquid phase comprises an aqueous phase; or said first liquid phase comprises an aqueous phase and said second liquid phase comprises a lipid phase; said method comprising controlling provision of the first liquid phase in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling provision of the second liquid phase to the membrane in a crossflow to the first flow direction, via the plurality of pores, to form a lipid vesicle suspension.
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