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    HYBRID ULTRAFAST LASER SURGERY AND GROWTH FACTOR STIMULATION FOR ULTRA-PRECISION SURGERY WITH HEALING
    1.
    发明申请
    HYBRID ULTRAFAST LASER SURGERY AND GROWTH FACTOR STIMULATION FOR ULTRA-PRECISION SURGERY WITH HEALING 审中-公开
    混合超声激光手术和生长因子刺激超声精密手术与治疗

    公开(公告)号：WO2007022616A2

    公开(公告)日：2007-03-01

    申请号：PCT/CA2006/001293

    申请日：2006-08-03

    Applicant: GIRARD, Bruno ,  CLOKIE, Cameron, ,  WILSON, Brian Campbell ,  MILLER, Robert John Dwayne

    Inventor： GIRARD, Bruno ,  CLOKIE, Cameron, ,  WILSON, Brian Campbell ,  MILLER, Robert John Dwayne

    IPC: A61B18/20 ,  A61K38/17 ,  A61K38/18 ,  A61K38/30 ,  A61P17/02 ,  A61P41/00

    CPC classification number: A61B18/20 ,  A61K38/1875 ,  B23K26/0624 ,  B23K2203/32 ,  B23K2203/50

    Abstract: The present invention relates to methods for laser surgery and growth factor stimulation for ultra-precision surgery with healing. The method is achieved by cutting biological tissue using an ultrafast laser, which produces laser pulses less than 10 picosecond in duration, to induce a cold ablation process in order to avoid the formation of carbonaceous or other materials that cannot be removed efficiently or completely from the wounded area through natural healing mechanisms. By use of femtosecond lasers, a negligible amount of debris is generated and an outer layer of intact but non viable cells are created principally through shock wave induce damage and ionizing radiation effects induced by multiphoton absorption of ultrashort laser pulses. The normal healing process is blocked by this outer layer of cells as all cell contacts are still intact. Therefore the healing process must be stimulated. The healing may be triggered or accelerated, or both, by application of growth factor molecules and/or signal proteins to the effectively undamaged cells causing the damaged cells to be replaced and the wound to close. The combination of very precise laser cutting used in combination with growth factors is the key to this unique tool.

    Abstract translation: 本发明涉及用于具有愈合的超精密手术的激光手术和生长因子刺激方法。 该方法通过使用超快激光切割生物组织来实现，该超快激光产生持续时间小于10皮秒的激光脉冲，以诱导冷消融过程，以避免形成不能有效或完全地从 受伤区域通过自然愈合机制。 通过使用飞秒激光器，产生可忽略量的碎片，并且主要通过冲击波诱发损伤和由超短激光脉冲的多光子吸收引起的电离辐射效应产生完整但不活细胞的外层。 正常的愈合过程被这个外层的细胞所阻挡，因为所有细胞接触仍然完整。 因此，必须刺激愈合过程。 通过将生长因子分子和/或信号蛋白应用于有效的未损伤的细胞，导致损伤的细胞被替换并且使伤口闭合，可以触发或加速愈合或两者。 与生长因子结合使用的非常精确的激光切割的组合是这种独特工具的关键。

    METHOD AND APPARATUS FOR HIGH POWER OPTICAL AMPLIFICATION IN THE INFRARED WAVELENGTH RANGE (0.7-20 μm)
    3.
    发明申请
    METHOD AND APPARATUS FOR HIGH POWER OPTICAL AMPLIFICATION IN THE INFRARED WAVELENGTH RANGE (0.7-20 μm) 审中-公开
    红外波长范围内高功率光学放大的方法和装置（0.7-20 mum）

    公开(公告)号：WO2005112207A1

    公开(公告)日：2005-11-24

    申请号：PCT/CA2005/000765

    申请日：2005-05-16

    Applicant: MILLER, Robert John Dwayne ,  FRANJIC, Kresimir ,  KRAEMER, Darren ,  PICHE, Michel

    Inventor： MILLER, Robert John Dwayne ,  FRANJIC, Kresimir ,  KRAEMER, Darren ,  PICHE, Michel

    IPC: H01S3/094

    CPC classification number: G02F1/39 ,  G02F2001/392 ,  H01S3/0057 ,  H01S3/109

    Abstract: Method for high power optical amplification of ultra-short pulses in IR wavelength range (0.7- 20 µm). The method is based on the optical parametric chirp pulse amplification (OPCPA) technique where a pico-second or nanosecond mode locked laser system synchronized to a signal laser oscillator is used as a pump source or alternatively the pump pulse is created from the signal pulse by using certain types of optical nonlinear processes described later in the document. This significantly increases stability, extraction efficiency and bandwidth of the amplified signal pulse.á Further, we disclose several practical methods of shaping the temporal and spatial profiles of the signal and pump pulses for optimization of the OPCPA interaction.

    Abstract translation: IR波长范围（0.7〜20μm）超短脉冲大功率光放大的方法。 该方法基于光学参量啁啾脉冲放大（OPCPA）技术，其中与信号激光振荡器同步的微秒级或纳秒模式锁定激光系统用作泵浦源，或者，泵浦脉冲是由信号脉冲由 使用文献中稍后描述的某些类型的光学非线性过程。 这显着增加了放大信号脉冲的稳定性，提取效率和带宽。此外，我们公开了形成信号和泵浦脉冲的时间和空间分布的几种实际方法，以优化OPCPA相互作用。

    MULTI-MODE RING SCANNER
    5.
    发明申请
    MULTI-MODE RING SCANNER 审中-公开
    多模式环形扫描仪

    公开(公告)号：WO2008070634A1

    公开(公告)日：2008-06-12

    申请号：PCT/US2007/086309

    申请日：2007-12-03

    Applicant: SOCKET COMMUNICATIONS, INC ,  MILLER, Robert, John ,  LEAFBLAD, Allan ,  NEWMAN, Thomas, J. ,  OTT, Leonard ,  BRANDON, John, E. ,  ADER, Charles, E. ,  MILLER, Timothy

    Inventor： MILLER, Robert, John ,  LEAFBLAD, Allan ,  NEWMAN, Thomas, J. ,  OTT, Leonard ,  BRANDON, John, E. ,  ADER, Charles, E. ,  MILLER, Timothy

    IPC: G06K7/10

    CPC classification number: G06K7/0004 ,  G06K7/10722 ,  G06K7/10891

    Abstract: A multi-mode ring scanner (MMRS) has a ring unit for wearing on a finger. The MMRS optionally has a wrist unit coupled to the ring unit, such as via a cable. The MMRS optionally communicates wirelessly with a computing device. The ring unit has one or more scanners (such as an optical scanner or an RFID tag reader). The ring unit optionally has two paddle switches for activation by inward pressure from fingers adjacent to the finger. The two switches enable specifying operation of the MMRS in a plurality of modes and/or to communicate a plurality of information codes to the computing device. The computing device is optionally enabled to assign a function to each combination of activation of the two switches. A scanning system including the MMRS optionally provides feedback to a user based on feedback from a host processor.

    Abstract translation: 多模式环形扫描器（MMRS）具有用于在手指上佩戴的环形单元。 MMRS可选地具有联接到环形单元的手腕单元，例如经由电缆。 MMRS可选地与计算设备进行无线通信。 环形单元具有一个或多个扫描仪（例如光学扫描仪或RFID标签读取器）。 环形单元可选地具有两个桨叶开关，用于通过邻近手指的手指的向内压力进行激活。 两个开关使得能够以多种模式指定MMRS的操作和/或将多个信息代码传送到计算设备。 可选地，计算设备能够为两个开关的激活的每个组合分配功能。 包括MMRS的扫描系统可选地基于来自主处理器的反馈向用户提供反馈。

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