公开(公告)号：WO2008125823A1

公开(公告)日：2008-10-23

申请号：PCT/GB2008/001280

申请日：2008-04-11

Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS ,  TAYSIDE HEALTH BOARD ,  THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW ,  SAMUEL, Ifor, Daniel, William ,  FERGUSON, James ,  MARSH, Paul, Nigel ,  PADGETT, Miles ,  O'DWYER, Martin

Inventor： SAMUEL, Ifor, Daniel, William ,  FERGUSON, James ,  MARSH, Paul, Nigel ,  PADGETT, Miles ,  O'DWYER, Martin

IPC: A61B5/00

CPC classification number: A61B5/0075 ,  A61B5/0071 ,  A61B5/443 ,  A61B5/444 ,  A61B5/4848 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6486

Abstract: Apparatus for analysing a biological substance comprises a probe (1) for directing light emitted by a light source onto an area of the substance to cause fluorescence at that area. The fluorescent light is received by receiving means in the probe and is conveyed to spectral analysis means (4; 1-8; 2-8) for use in analysing the spectrum of the received fluorescent light and temporal analysis means (8, 10; 118) for analysing temporal characteristics of the received fluorescent light. The use of common receiving means ensures that the temporal and spectral analyses are conducted on the same area, and both types of analysis can, in combination, provide more information on the area being analysed than each individual type of analysis. Apparatus for analysing a biological substance by causing a substance to fluoresce and measuring characteristics of the resultant fluorescent light may have spectral analysis means and temporal analysis means, wherein the spectral analysis means is connected to the temporal analysis means so as to select the wavelength of the received light to be analysed by the temporal analysis means.

Abstract translation: 用于分析生物物质的装置包括用于将由光源发射的光引导到物质的区域上以在该区域引起荧光的探针（1）。 荧光由探头中的接收装置接收并被传送到频谱分析装置（4; 1-8; 2-8），用于分析所接收的荧光的光谱和时间分析装置（8,10; 118 ），用于分析所接收的荧光的时间特性。 使用通用接收装置确保时间和频谱分析在相同的区域进行，并且两种类型的分析可以组合地提供关于正在分析的区域的更多信息，而不是每种单独的分析类型。 用于通过使物质发荧光并测量所得荧光的特性来分析生物物质的装置可以具有光谱分析装置和时间分析装置，其中光谱分析装置连接到时间分析装置，以便选择 接收光通过时间分析手段进行分析。