公开(公告)号：WO2013027214A3

公开(公告)日：2013-07-04

申请号：PCT/IL2012050317

申请日：2012-08-19

申请人： UNIV BAR ILAN ,  POPOVTZER RACHEL ,  MACHTEY YOSEPH

发明人： POPOVTZER RACHEL ,  MACHTEY YOSEPH

IPC分类号： A61M1/34 ,  A61M1/36

CPC分类号： A61M1/3472 ,  A61M1/3475 ,  A61M1/3486 ,  A61M1/3493 ,  A61M1/3679 ,  A61M2205/3592 ,  A61M2209/088

摘要： According to an aspect of some embodiments of the present invention there is provided a device configured for selective removal of target substances from a patient's blood, the device comprising: an inlet configured for letting the patient's blood enter the device; an outlet configured for letting the patient's blood exit the device; a chamber adapted for containing fluid; particles disposed in the chamber, the particles adapted for selectively binding to the target substances; and a membrane positioned so that at least the target substances can move from the blood across the membrane into the chamber, the membrane having pores with a size small enough to prevent the particles from entering the blood, the pores are small enough to prevent cellular components from entering the chamber, the pores are large enough to allow molecules having a size at least over 25000 Dalton to enter the chamber.

摘要翻译： 根据本发明的一些实施例的一个方面，提供了一种被配置为从患者血液中选择性去除目标物质的装置，该装置包括：入口，被配置为使患者的血液进入该装置; 用于使患者血液离开装置的出口; 适合容纳流体的室; 设置在室中的颗粒，适于选择性地结合目标物质的颗粒; 以及膜，其定位成使得至少目标物质可以从穿过膜的血液移动到腔室中，该膜具有尺寸足够小以防止颗粒进入血液的孔，孔足够小以防止细胞组分 进入腔室时，孔隙足够大，使得尺寸至少超过25000道尔顿的分子进入腔室。

公开(公告)号：WO2013027214A2

公开(公告)日：2013-02-28

申请号：PCT/IL2012/050317

申请日：2012-08-19

申请人： BAR-ILAN UNIVERSITY ,  POPOVTZER, Rachel ,  MACHTEY, Yoseph

发明人： POPOVTZER, Rachel ,  MACHTEY, Yoseph

IPC分类号： A61M1/34 ,  A61M1/36

CPC分类号： A61M1/3472 ,  A61M1/3475 ,  A61M1/3486 ,  A61M1/3493 ,  A61M1/3679 ,  A61M2205/3592 ,  A61M2209/088

摘要： According to an aspect of some embodiments of the present invention there is provided a device configured for selective removal of target substances from a patient's blood, the device comprising: an inlet configured for letting the patient's blood enter the device; an outlet configured for letting the patient's blood exit the device; a chamber adapted for containing fluid; particles disposed in the chamber, the particles adapted for selectively binding to the target substances; and a membrane positioned so that at least the target substances can move from the blood across the membrane into the chamber, the membrane having pores with a size small enough to prevent the particles from entering the blood, the pores are small enough to prevent cellular components from entering the chamber, the pores are large enough to allow molecules having a size at least over 25000 Dalton to enter the chamber.

摘要翻译： 根据本发明的一些实施方式的一个方面，提供了一种被配置用于从患者血液中选择性去除目标物质的装置，所述装置包括：入口，其被配置用于使患者的血液进入 设备; 配置用于让患者的血液离开装置的出口; 适合于容纳流体的腔室; 置于腔室中的颗粒，所述颗粒适于选择性结合目标物质; 以及定位膜使得至少目标物质可以从血液移动穿过膜进入腔室，膜具有足够小的孔以防止颗粒进入血液，孔足够小以防止细胞组分 从进入腔室，孔隙足够大以允许尺寸至少超过25000道尔顿的分子进入腔室。