公开(公告)号：WO2006006071A1

公开(公告)日：2006-01-19

申请号：PCT/IB2005/002082

申请日：2005-06-27

Applicant: PFIZER PRODUCTS INC. ,  MCDERMOTT, Ruth, Elsbree ,  MCKINLEY, Jason, Daniel ,  RAGAN, John, Anthony ,  WHRITENOUR, David, Curtis

Inventor： MCDERMOTT, Ruth, Elsbree ,  MCKINLEY, Jason, Daniel ,  RAGAN, John, Anthony ,  WHRITENOUR, David, Curtis

IPC: C07D221/22

CPC classification number: C07D221/22 ,  C07D221/24

Abstract: A process of obtaining an enantiomerically enriched salt from a recamic mixture of a compound of formula (I), wherein R is hydrogen or benzyl.

Abstract translation: 从式（I）化合物的反应混合物中获得对映体富集的盐的方法，其中R是氢或苄基。

公开(公告)号：WO2006043175A3

公开(公告)日：2006-07-20

申请号：PCT/IB2005003255

申请日：2005-10-10

Applicant: PFIZER PROD INC ,  RAGAN JOHN ANTHONY

Inventor： RAGAN JOHN ANTHONY

IPC: C07D487/04

CPC classification number: C07D487/04

Abstract: A process for preparing compounds of Formula (I) are described herein as well as key intermediates 1.

Abstract translation: 本文描述了制备式（I）化合物的方法以及关键中间体1。

公开(公告)号：WO2005037790A1

公开(公告)日：2005-04-28

申请号：PCT/IB2004/003261

申请日：2004-10-06

Applicant: PFIZER PRODUCTS INC. ,  COE, Jotham, Wadsworth ,  MCHARDY, Stanton, Furst ,  RAGAN, John, Anthony ,  TICKNER, Derek, Lawrence ,  VANDERPLAS, Brian, Clement

Inventor： COE, Jotham, Wadsworth ,  MCHARDY, Stanton, Furst ,  RAGAN, John, Anthony ,  TICKNER, Derek, Lawrence ,  VANDERPLAS, Brian, Clement

IPC: C07D209/52

CPC classification number: C07D209/52

Abstract: This present invention relates to a new and improved reductive amination process for the preparation of 3-azabicyclo[3.1.0]hexane derivatives of formula I comprising reacting a compound of formula II with a compound of formula III.

Abstract translation: 本发明涉及用于制备式I的3-氮杂双环[3.1.0]己烷衍生物的新的和改进的还原胺化方法，包括使式II化合物与式III化合物反应。

公开(公告)号：WO2006043175A2

公开(公告)日：2006-04-27

申请号：PCT/IB2005/003255

申请日：2005-10-10

Applicant: PFIZER PRODUCTS INC. ,  RAGAN, John, Anthony

Inventor： RAGAN, John, Anthony

IPC: C07D487/04

CPC classification number: C07D487/04

Abstract: A process for preparing compounds of Formula (I) are described herein as well as key intermediates.

Abstract translation: 本文描述了制备式（I）化合物的方法以及关键中间体。