STABILIZED AMYLOID- β OLIGOMERS AND USES THEREOF
    4.
    发明申请
    STABILIZED AMYLOID- β OLIGOMERS AND USES THEREOF 审中-公开
    稳定的AMYLOID-ß低聚物及其用途

    公开(公告)号:WO2011149917A1

    公开(公告)日:2011-12-01

    申请号:PCT/US2011/037711

    申请日:2011-05-24

    CPC classification number: C07K14/4711 C07K1/14

    Abstract: The present invention pertains to stabilized Αβ oligomer compositions. Methods for generating stabilized Αβ oligomer compounds are also provided herein. Additionally, screening assays employing the Αβ oligomer compounds and methods for generating therapeutics with the Αβ oligomers are also provided. In a particular embodiment, the Αβ oligomer described herein is comprised of Αβ42 peptide.

    Abstract translation: 本发明涉及稳定的β低聚物组合物。 本文还提供了产生稳定的β低聚物化合物的方法。 此外,还提供了使用β低聚物化合物的筛选测定法和用β-低聚物产生治疗剂的方法。 在一个具体的实施方案中,本文所述的β低聚物由β42肽组成。

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