公开(公告)号：WO2004071641A3

公开(公告)日：2005-02-24

申请号：PCT/US0334747

申请日：2003-10-30

Applicant: POINTILLISTE INC ,  AULT-RICHE DANA ,  KUMBLE KRISHNANAND D ,  SCHULZ RAINER ,  SCHULZ KENNETH

Inventor： AULT-RICHE DANA ,  KUMBLE KRISHNANAND D ,  SCHULZ RAINER ,  SCHULZ KENNETH

IPC: B01J20060101 ,  G01N33/53 ,  G01N33/543

CPC classification number: G01N33/54353

Abstract: Provided herein are methods, combinations, kits and systems for self-assembly of a self-assembling array to produce self-assembled arrays. The self-assembling arrays contain addressed collections of capture agents and are used with binding partners and reagents for conjugation of binding partners or molecules and/or biological particles for display in self-assembled arrays. The capture agents at each locus in a self-assembling array are specific to one of a set of binding partner molecules. The binding partners are conjugated to molecules and/or biological particles for display. Following conjugation, the resulting conjugates are sorted on the array based on the specific interaction of the binding partner and the capture agent to produce a self-assembled array.

Abstract translation: 本文提供了用于自组装阵列自组装以产生自组装阵列的方法，组合，套件和系统。 自组装阵列包含寻址的捕获剂的集合，并且与结合配偶体和试剂一起使用，用于结合配偶体或分子和/或生物颗粒的缀合以在自组装阵列中显示。 自组装阵列中每个位点的捕获剂对一组结合配偶体分子之一是特异性的。 结合配偶体与分子和/或生物颗粒缀合以进行显示。 在共轭之后，基于结合配偶体和捕获剂的特异性相互作用，将所得到的缀合物在阵列上进行分选以产生自组装阵列。

公开(公告)号：WO2004042561A3

公开(公告)日：2004-05-21

申请号：PCT/US2003/034555

申请日：2003-10-31

Applicant: LOCKHEED MARTIN CORPORATION ,  SCHULZ, Kenneth, R. ,  RAPP, John, W. ,  JACKSON, Larry ,  JONES, Mark ,  CHERASARO, Troy

Inventor： SCHULZ, Kenneth, R. ,  RAPP, John, W. ,  JACKSON, Larry ,  JONES, Mark ,  CHERASARO, Troy

IPC: G06F15/80

Abstract: A pipeline accelerator includes a bus and a plurality of pipeline units, each unit coupled to the bus and including at least one respective hardwired-pipeline circuit. By including a plurality of pipeline units in the pipeline accelerator, one can increase the accelerator's data-processing performance as compared to a single-pipeline-unit accelerator. Furthermore, by designing the pipeline units so that they communicate via a common bus, one can alter the number of pipeline units, and thus alter the configuration and functionality of the accelerator, by merely coupling or uncoupling pipeline units to or from the bus. This eliminates the need to design or redesign the pipeline-unit interfaces each time one alters one of the pipeline units or alters the number of pipeline units within the accelerator.

公开(公告)号：WO2004071641A2

公开(公告)日：2004-08-26

申请号：PCT/US2003/034747

申请日：2003-10-30

Applicant: POINTILLISTE, INC. ,  AULT-RICHE, Dana ,  KUMBLE, Krishnanand, D. ,  SCHULZ, Rainer ,  SCHULZ, Kenneth

Inventor： AULT-RICHE, Dana ,  KUMBLE, Krishnanand, D. ,  SCHULZ, Rainer ,  SCHULZ, Kenneth

IPC: B01J

CPC classification number: G01N33/54353

Abstract: Provided herein are methods, combinations, kits and systems for self-assembly of a self-assembling array to produce self-assembled arrays. The self-assembling arrays contain addressed collections of capture agents and are used with binding partners and reagents for conjugation of binding partners or molecules and/or biological particles for display in self-assembled arrays. The capture agents at each locus in a self-assembling array are specific to one of a set of binding partner molecules. The binding partners are conjugated to molecules and/or biological particles for display. Following conjugation, the resulting conjugates are sorted on the array based on the specific interaction of the binding partner and the capture agent to produce a self-assembled array.

Abstract translation: 本文提供了用于自组装阵列自组装以产生自组装阵列的方法，组合，套件和系统。 自组装阵列包含寻址的捕获剂的集合，并且与结合配偶体和试剂一起使用，用于结合配偶体或分子和/或生物颗粒的缀合以在自组装阵列中显示。 自组装阵列中每个位点的捕获剂对一组结合配偶体分子之一是特异性的。 结合配偶体与分子和/或生物颗粒缀合以进行显示。 在共轭之后，基于结合配偶体和捕获剂的特异性相互作用，将所得到的缀合物在阵列上进行分选以产生自组装阵列。

公开(公告)号：WO2004042561A2

公开(公告)日：2004-05-21

申请号：PCT/US0334555

申请日：2003-10-31

Applicant: LOCKHEED CORP ,  SCHULZ KENNETH R ,  RAPP JOHN W ,  JACKSON LARRY ,  JONES MARK ,  CHERASARO TROY

Inventor： SCHULZ KENNETH R ,  RAPP JOHN W ,  JACKSON LARRY ,  JONES MARK ,  CHERASARO TROY

IPC: G06F9/30 ,  G06F9/38 ,  G06F9/445 ,  G06F9/46 ,  G06F15/78

CPC classification number: G06F9/3879

Abstract: A pipeline accelerator includes a bus and a plurality of pipeline units, each unit coupled to the bus and including at least one respective hardwired-pipeline circuit. By including a plurality of pipeline units in the pipeline accelerator, one can increase the accelerator's data-processing performance as compared to a single-pipeline-unit accelerator. Furthermore, by designing the pipeline units so that they communicate via a common bus, one can alter the number of pipeline units, and thus alter the configuration and functionality of the accelerator, by merely coupling or uncoupling pipeline units to or from the bus. This eliminates the need to design or redesign the pipeline-unit interfaces each time one alters one of the pipeline units or alters the number of pipeline units within the accelerator.

Abstract translation: 流水线加速器包括总线和多个流水线单元，每个单元耦合到总线并且包括至少一个相应的硬连线流水线电路。 通过在流水线加速器中包括多个流水线单元，与单管道单元加速器相比，可以增加加速器的数据处理性能。 此外，通过设计流水线单元使得它们通过公共总线进行通信，只需将流水线单元耦合或从母线解耦即可改变流水线单元的数量，从而改变加速器的配置和功能。 这样就无需设计或重新设计流水线单元接口，每次更换流水线单元之一或改变加速器中的流水线单元数量。