公开(公告)号：WO2005051360A1

公开(公告)日：2005-06-09

申请号：PCT/IB2004/003863

申请日：2004-11-24

Applicant: RANBAXY LABORATORIES LIMITED ,  SINGH, Romi, Barat ,  SHILPA, Anu ,  PRASAD, Vishnubhotla, Naga ,  SETHI, Sanjeev, Kumar

Inventor： SINGH, Romi, Barat ,  SHILPA, Anu ,  PRASAD, Vishnubhotla, Naga ,  SETHI, Sanjeev, Kumar

IPC: A61K9/20

CPC classification number: A61K31/198 ,  A61K9/2004

Abstract: The present invention relates to pharmaceutical compositions comprising nateglinide in combination with a surfactant, and processes for their preparation.

Abstract translation: 本发明涉及包含那格列奈与表面活性剂组合的药物组合物及其制备方法。

公开(公告)号：WO2005016315A1

公开(公告)日：2005-02-24

申请号：PCT/IB2004/002654

申请日：2004-08-13

Applicant: RANBAXY LABORATORIES LIMITED ,  SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla ,  SETHI, Sanjeev, Kumar

Inventor： SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla ,  SETHI, Sanjeev, Kumar

IPC: A61K9/20

CPC classification number: A61K31/00 ,  A61K9/2009 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054

Abstract: The present invention relates to pharmaceutical compositions of Nateglinide with 50-70% of water-soluble filler such as lactose alone or in combination with a channeling agent such as sodium chloride or compressible sugar. These compositions may have a dissolution profile wherein at least 70% by weight of Nateglinide is released within 45 minute period.

Abstract translation: 本发明涉及那格列奈的药物组合物，其具有50-70％的水溶性填料，例如单独的乳糖或与窜流剂如氯化钠或可压缩糖组合。 这些组合物可具有溶解曲线，其中至少70重量％的那格列奈在45分钟内释放。

公开(公告)号：WO2005020979A1

公开(公告)日：2005-03-10

申请号：PCT/IB2004/051678

申请日：2004-09-02

Applicant: RANBAXY LABORATORIES LIMITED ,  SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla ,  SETHI, Sanjeev, Kumar

Inventor： SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla ,  SETHI, Sanjeev, Kumar

IPC: A61K31/198

CPC classification number: A61K31/198 ,  A61K9/1611 ,  A61K9/1652 ,  A61K9/2009 ,  A61K9/2054

Abstract: The present invention relates to a pharmaceutical composition comprising nateglinide, and a process for its preparation.

Abstract translation: 本发明涉及包含那格列奈的药物组合物及其制备方法。

公开(公告)号：WO2005117840A1

公开(公告)日：2005-12-15

申请号：PCT/IB2005/051750

申请日：2005-05-27

Applicant: RANBAXY LABORATORIES LIMITED ,  SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla

Inventor： SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla

IPC: A61K9/20

CPC classification number: A61K9/2018 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/1694 ,  A61K9/2054 ,  A61K9/2095

Abstract: The present invention relates to stable pharmaceutical compositions comprising nateglinide of Form B and processes for making them which include a step of pulverization.

Abstract translation: 本发明涉及稳定的药物组合物，其包含形式B的那格列奈及其制备方法，其包括粉碎步骤。

公开(公告)号：WO2005092319A1

公开(公告)日：2005-10-06

申请号：PCT/IB2005/000814

申请日：2005-03-29

Applicant: RANBAXY LABORATORIES LIMITED ,  SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla

Inventor： SINGH, Romi, Barat ,  SHILPA, Anu ,  NAGAPRASAD, Vishnubhotla

IPC: A61K31/198

CPC classification number: A61K31/198 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2059

Abstract: The present invention relates to rapidly disintegrating pharmaceutical compositions of nateglinide and processes for their preparation. The rapidly disintegrating pharmaceutical compositions include nateglinide and a disintegrant selected from sodium starch glycolate, crospovidone and mixtures thereof.

Abstract translation: 本发明涉及那格列奈的快速崩解药物组合物及其制备方法。 快速崩解的药物组合物包括那格列奈和选自淀粉羟乙酸钠，交聚维酮及其混合物的崩解剂。