Abstract:
An ingestible device includes a sample chamber configured to hold a sample, the sample chamber including a base having an aperture; a fluorometer separated from the sample chamber by the sample chamber base, the fluorometer including (I) a light source configured to emit excitation light, (II) a light guide configured to guide the excitation light from the light source to the sample, (III) a photodetector configured to detect emission light generated via the interaction of the excitation light with the sample. The photodetector is configured to receive the emission light from the sample through the aperture. Additionally, the fluorometer includes (IV) an emission filter between the aperture and the photodetector, the emission filter configured to (i) transmit the emission light incident thereon, and (ii) block excitation light incident thereon. In addition, the ingestible device includes a housing that houses the sample chamber and the fluorometer.
Abstract:
An image projection system includes a liquid crystal on silicon (LCOS) panel (504), a projection lens assembly (505), and a wire-grid PBS (503) disposed to direct at least a portion of source light towards the LCOS panel (504), and to direct a portion of light reflected from the LCOS panel (504) to the projection lens assembly (504). In addition, a field léns (506) and a quarter-wave retarder (507) are optically interposed between the LCOS panel (504) and the wire-grid PBS (503). The insertion of the quarter wave retarder (507) between the LCOS panel (504) and wire-grid PBS (503) helps improve contrast by correcting polarization aberrations otherwise caused by the nontelecentricity of the field lens (506).
Abstract:
In a LCD (Liquid Crystal Display), uniformity correction of black and white is employed to improve picture quality and contrast. Extending the drive range and allocating a few gray scale levels to this extended range can accomplish the correction without penalty to contrast. Such an arrangement can be particularly helpful for projection display systems such as those based on LCOS (liquid crystal on silicon).
Abstract:
Backlighting is provided for a display panel display by directing light from a source (10) via rotating means (16, 30) to plurality of optical wave guides (24) which are positioned with one end (24') towards said means and the other end (24") attached along one edge (26') of the panel (26) to which backlighting is provided. The beam is rotated providing light sequentially to each of the wave guides (24) with resulting scrolling of the light across the panel (26) behind the display panel array.
Abstract:
Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.