公开(公告)号：WO2011025649A1

公开(公告)日：2011-03-03

申请号：PCT/US2010/044966

申请日：2010-08-10

Applicant: PPG INDUSTRIES OHIO, INC. ,  CHENG, Shan ,  HOCKSWENDER, Thomas R. ,  CHASSER, Anthony M. ,  ROWLEY, James P. ,  SIMPSON, Dennis A.

Inventor： CHENG, Shan ,  HOCKSWENDER, Thomas R. ,  CHASSER, Anthony M. ,  ROWLEY, James P. ,  SIMPSON, Dennis A.

IPC: C08L63/00

CPC classification number: C08G59/306 ,  C08G59/3254 ,  C08L63/00 ,  C09D163/00 ,  Y10T428/249991 ,  Y10T428/31511 ,  Y10T428/31525 ,  Y10T428/31529 ,  Y10T442/20 ,  C08L2666/22

Abstract: Film-forming coating compositions are disclosed. The composition comprises a) an epoxy-containing polymer system; and b) a polyacid curing agent comprising two acid functional groups per molecule; wherein the epoxy-containing polymer system comprises: (i) an epoxy resin comprising at least two epoxy functional groups per molecule and which is different from (ii); and (ii) an epoxy functional silsesquioxane. Also disclosed are processes for applying the film-forming composition to a basecoat, and substrates coated in part by a coating deposited from the film-forming compositions.

Abstract translation: 公开了成膜涂料组合物。 该组合物包含a）含环氧基的聚合物体系; 和b）每分子含有两个酸官能团的多元酸固化剂; 其中所述含环氧基的聚合物体系包括：（i）每分子包含至少两个环氧官能团并且不同于（ⅱ）的环氧树脂; 和（ii）环氧官能硅倍半氧烷。 还公开了将成膜组合物施用于底涂层的方法，以及通过由成膜组合物沉积的涂层部分涂覆的基材。

公开(公告)号：WO9836779A3

公开(公告)日：1999-04-22

申请号：PCT/US9802945

申请日：1998-02-18

Applicant: UNIV NORTH CAROLINA ,  JOHNSTON ROBERT E ,  DAVIS NANCY L ,  SIMPSON DENNIS A

Inventor： JOHNSTON ROBERT E ,  DAVIS NANCY L ,  SIMPSON DENNIS A

IPC: C12N15/09 ,  A61K31/7105 ,  A61K35/76 ,  A61K48/00 ,  A61P31/12 ,  C07K14/18 ,  C12N5/10 ,  C12N7/00 ,  C12N15/86 ,  A61K39/12 ,  C12N7/01 ,  C12N15/33

CPC classification number: C07K14/005 ,  A61K48/00 ,  C12N15/86 ,  C12N2770/36122 ,  C12N2770/36143

Abstract: The present invention provides a method of delivering immunogenic or therapeutic proteins to bone marrow cells using alphavirus vectors. The alphavirus vectors disclosed herein target specifically to bone marrow tissue, and viral genomes persist in bone marrow for at least three months post-infection. No or very low levels of virus were detected in quadricep, brain, and sera of treated animals. The sequence of a consensus Sindbis cDNA clone, pTR339, and infectious RNA transcripts, infectious virus particles, and pharmaceutical formulations derived therefrom are also disclosed. The sequence of the genomic RNA of the Girdwood S.A. virus, and cDNA clones, infectious RNA transcripts, infectious virus particles, and pharmaceutical formulations derived therefrom are also disclosed.

Abstract translation: 本发明提供使用甲病毒载体将免疫原性或治疗性蛋白递送至骨髓细胞的方法。 本文公开的甲病毒载体特异性靶向骨髓组织，并且病毒基因组在感染后至少三个月持续存在于骨髓中。 在经治疗的动物的四头肌，脑和血清中检测不到或非常低水平的病毒。 还公开了一致的辛德毕斯cDNA克隆，pTR339和感染性RNA转录物，感染性病毒颗粒和由其衍生的药物制剂的序列。 还公开了Girdwood S.A.病毒和cDNA克隆，感染性RNA转录物，感染性病毒颗粒和由其衍生的药物制剂的基因组RNA的序列。

公开(公告)号：WO2012078681A1

公开(公告)日：2012-06-14

申请号：PCT/US2011/063605

申请日：2011-12-06

Applicant: PPG INDUSTRIES OHIO, INC. ,  FUHRY, Mary Ann M. ,  FENN, David R. ,  DUDIK, John M. ,  ANDERSON, Linda K. ,  WANG, Wei ,  SIMPSON, Dennis A. ,  MORAVEK, Scott J. ,  NIEDERST, Ken W.

Inventor： FUHRY, Mary Ann M. ,  FENN, David R. ,  DUDIK, John M. ,  ANDERSON, Linda K. ,  WANG, Wei ,  SIMPSON, Dennis A. ,  MORAVEK, Scott J. ,  NIEDERST, Ken W.

IPC: C09D7/04 ,  C09D7/06 ,  C09D7/12

CPC classification number: C08J7/047 ,  C08J2433/12 ,  C09D7/20 ,  C09D7/65 ,  C09D133/08 ,  C09D133/10

Abstract: A non-aqueous dispersion comprising the dispersion polymerization reaction product of an ethylenically unsaturated monomer and a nonlinear, random acrylic polymer stabilizer is disclosed. Related coatings, methods, and substrates are also disclosed.

Abstract translation: 公开了包含烯属不饱和单体和非线性无规丙烯酸类聚合物稳定剂的分散聚合反应产物的非水分散体。 还公开了相关涂料，方法和基材。

公开(公告)号：WO2011123632A1

公开(公告)日：2011-10-06

申请号：PCT/US2011/030709

申请日：2011-03-31

Applicant: PPG INDUSTRIES OHIO, INC. ,  SINGER, Debra L. ,  SIMPSON, Dennis A. ,  DUDIK, John M. ,  CHASSER, Anthony M. ,  LOCK, Kam Lun ,  WOODS, Richard ,  MASTERS, Nigel Francis

Inventor： SINGER, Debra L. ,  SIMPSON, Dennis A. ,  DUDIK, John M. ,  CHASSER, Anthony M. ,  LOCK, Kam Lun ,  WOODS, Richard ,  MASTERS, Nigel Francis

IPC: B65D25/14 ,  C08F299/04 ,  C08G63/52 ,  C09D167/00

CPC classification number: C09D167/06 ,  C08F299/04 ,  Y10T428/1355 ,  Y10T428/31786

Abstract: A polyester prepared by free radical polymerization of an unsaturated polyester prepolymer, wherein the polymerization occurs primarily by reaction of the unsaturation is disclosed. Coatings comprising the same are also disclosed, as are substrates coated at least in part with such coatings.

Abstract translation: 公开了通过不饱和聚酯预聚物的自由基聚合制备的聚酯，其中聚合主要通过不饱和键的反应而发生。 还公开了包含该涂层的涂层，以及至少部分地涂覆有这样的涂层的基材。

公开(公告)号：WO2011056555A1

公开(公告)日：2011-05-12

申请号：PCT/US2010/054065

申请日：2010-10-26

Applicant: PPG INDUSTRIES OHIO, INC. ,  SCHMELTZER, Robert ,  DONALDSON, Susan F. ,  OLSON, Kevin C. ,  OLSON, Kurt G. ,  SCHWENDEMAN, John E. ,  SIMPSON, Dennis A. ,  WILLIAMS, Frank C.

Inventor： SCHMELTZER, Robert ,  DONALDSON, Susan F. ,  OLSON, Kevin C. ,  OLSON, Kurt G. ,  SCHWENDEMAN, John E. ,  SIMPSON, Dennis A. ,  WILLIAMS, Frank C.

IPC: C09D183/04 ,  C09D183/06 ,  C09D183/08 ,  C08G18/83 ,  C09D201/10

CPC classification number: C09D183/04 ,  C08G18/792 ,  C08K3/22 ,  C08K3/36 ,  C09D183/06 ,  C09D183/08 ,  C09D201/10 ,  C08L2666/02

Abstract: The present invention is directed to a coating composition, such as a substantially clear coating composition, which comprises (1) an alkoxysilane, (2) a polysiloxane, (3) a plurality of particles, and (4) curing agent that is reactive with the polysiloxane. The coating composition of the present invention can exhibit increased physical properties, such as scratch resistance, when compared to similar coating compositions that lack the components disclosed herein.

Abstract translation: 本发明涉及涂料组合物，例如基本上透明的涂料组合物，其包括（1）烷氧基硅烷，（2）聚硅氧烷，（3）多个颗粒，和（4）与 聚硅氧烷。 当与缺乏本文公开的组分的类似涂料组合物相比时，本发明的涂料组合物可以表现出增加的物理性能，例如耐刮擦性。

公开(公告)号：WO1996037220A1

公开(公告)日：1996-11-28

申请号：PCT/US1996007457

申请日：1996-05-22

Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ,  JOHNSTON, Robert, E. ,  DAVIS, Nancy, L. ,  SIMPSON, Dennis, A.

Inventor： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

IPC: A61K39/12

CPC classification number: C07K14/005 ,  A61K39/00 ,  C12N2770/36122

Abstract: The present invention provides a recombinant DNA comprising a cDNA coding for an infectious South African Arbovirus No. 86 (S.A.AR86) virus RNA transcript and a heterologous promoter positioned upstream from the cDNA and operatively associated therewith. The present invention also provides an infectious RNA transcript encoded by the cDNA, and infectious attenuated viral particles produced from cells transfected with the RNA transcript encoded by the cDNA.

Abstract translation: 本发明提供了一种重组DNA，其包含编码感染性南非野兽病毒86号（S.A.AR86）病毒RNA转录物的cDNA和位于cDNA上游并与其可操作地相关联的异源启动子。 本发明还提供了由cDNA编码的感染性RNA转录物和由由cDNA编码的RNA转录物转染的细胞产生的感染性减毒病毒颗粒。