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公开(公告)号：WO2021154102A1
公开(公告)日：2021-08-05
申请号：PCT/NZ2021/050012
申请日：2021-01-29
Applicant: DAVIS, Paul Frank , MACKAY, Sean Marshall , PATERSON, Erin Fay , TAN, Swee Thong , TAN, Eng Wui
Inventor： DAVIS, Paul Frank , MACKAY, Sean Marshall , PATERSON, Erin Fay , TAN, Swee Thong , TAN, Eng Wui
IPC: A61K31/138 , A61K31/40 , A61K31/403 , A61K31/41 , A61K31/433 , A61K31/435 , A61K31/513 , A61K31/551 , A61K9/00 , A61K9/06 , A61K9/127 , A61P17/02 , A61P35/00
Abstract: The present invention relates to methods and compositions for the treatment of hemangioma, and particularly, but not exclusively, methods and compositions for the treatment of infantile hemangioma. In certain aspects, the methods comprise locally administering an ACE inhibitor or an ATIIR2 antagonist to a subject. In other aspects, the methods comprise systemically administering two or more of an ACE inhibitor, a beta-blocker and an ATIIR2 antagonist. The present invention also relates to compositions that are suitable for local administration and comprise: an ACEi and a beta-blocker; an ACEi and an ATIIR2 antagonist; a beta-blocker and an AT11R2 antagonist; or, an ACEi, a beta-blocker, and an AT11R2 antagonist.
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公开(公告)号：WO2017034418A1
公开(公告)日：2017-03-02
申请号：PCT/NZ2016/050130
申请日：2016-08-19
Applicant: REYNOLDS, John Noble James , TAN, Eng Wui , HYLAND, Brian Ian , JAMESON, Guy Nicholas Louis , MYINT, Maung Mo Aung , MACKAY, Sean Marshall , WICKENS, Jeffery Russell
Inventor： REYNOLDS, John Noble James , TAN, Eng Wui , HYLAND, Brian Ian , JAMESON, Guy Nicholas Louis , MYINT, Maung Mo Aung , MACKAY, Sean Marshall , WICKENS, Jeffery Russell
CPC classification number: A61K41/0028 , A61K9/0009 , A61K9/127 , A61K9/5115
Abstract: The present invention provides acoustically activated liposome compositions for use as drug delivery vehicles, and to methods for drug release and drug delivery for therapeutic applications.
Abstract translation: 本发明提供用作药物递送载体的声学活化的脂质体组合物，以及用于治疗应用的药物释放和药物递送的方法。
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