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1.COMBINATION COMPOSITIONS OF CAMPTOTHECINS AND FLUOROPYRIMIDINES 审中-公开
Title translation: CAMPTOTHECINS和氟氟吡啶的组合组成公开(公告)号:WO2004087115A2
公开(公告)日:2004-10-14
申请号:PCT/CA2004000507
申请日:2004-04-02
Applicant: CELATOR TECHNOLOGIES INC , MAYER LAWRENCE , BALLY MARCEL , WEBB MURRAY , TARDI PAUL , JOHNSTONE SHARON
Inventor: MAYER LAWRENCE , BALLY MARCEL , WEBB MURRAY , TARDI PAUL , JOHNSTONE SHARON
CPC classification number: A61K31/4745 , A61K9/127 , A61K31/7072 , A61K2300/00
Abstract: Compositions which comprise liposomes having stably associated therewith a camptothecin and a fluoropyrimidine are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered.
Abstract translation: 包含稳定与喜树碱相关的脂质体和氟嘧啶的组合物在施用这些药物的组合时可用于获得增强的治疗效果。
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2.COMBINATION FORMULATIONS OF PLATINUM AGENT AND FLUOROPYRIMIDINES 审中-公开
Title translation: 白蛋白剂和氟维酮的组合制剂公开(公告)号:WO2004087105A1
公开(公告)日:2004-10-14
申请号:PCT/CA2004/000508
申请日:2004-04-02
Applicant: CELATOR TECHNOLOGIES INC. , MAYER, Lawrence , BALLY, Marcel , WEBB, Murray , TARDI, Paul , SHEW, Clifford
Inventor: MAYER, Lawrence , BALLY, Marcel , WEBB, Murray , TARDI, Paul , SHEW, Clifford
IPC: A61K9/127
CPC classification number: A61K9/127 , A61K9/1271 , A61K33/24 , A61K45/06 , A61K2300/00
Abstract: Compositions which comprise liposomes having stably associated therewith a platinum agent and an antimetabolite are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered.
Abstract translation: 包含与铂剂和抗代谢物稳定相关的脂质体的组合物在施用这些药物的组合时可用于获得增强的治疗效果。
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公开(公告)号:WO2006081354A3
公开(公告)日:2006-08-03
申请号:PCT/US2006/002782
申请日:2006-01-26
Applicant: CELATOR PHARMACEUTICALS, INC. , TARDI, Paul , MAYER, Lawrence , CABRAL-LILLY, Donna
Inventor: TARDI, Paul , MAYER, Lawrence , CABRAL-LILLY, Donna
IPC: A61K9/127
Abstract: The invention relates to a method for reducing the polydispersity of a population of gel-phase lipid-based delivery vehicles.
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公开(公告)号:WO2004093795A3
公开(公告)日:2005-04-07
申请号:PCT/US2004011812
申请日:2004-04-16
Applicant: CELATOR TECHNOLOGIES INC , TARDI PAUL , HARASYM TROY , WEBB MURRAY , SHEW CLIFFORD , JANOFF PAUL
Inventor: TARDI PAUL , HARASYM TROY , WEBB MURRAY , SHEW CLIFFORD , JANOFF PAUL
IPC: A61K20060101 , A61K9/00 , A61K9/127 , A61K9/14 , A61K9/50 , A61K31/00 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06
CPC classification number: A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/282 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
Abstract translation: 包含与两种或多种试剂(例如抗肿瘤剂)的非拮抗组合稳定相关的递送载体的组合物在施用药物组合时可用于实现非拮抗作用。
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5.NANO-SIZED VEHICLES TRANSPORTING A THERAPEUTIC AGENT AND AT LEAST ONE DRUG RESISTANCE MODULATOR FOR THE TREATMENT OF MULTI DRUG RESISTANCE 审中-公开
Title translation: 纳米级车辆运输治疗药物和至少一种用于治疗多药耐药性的药物阻力调节剂公开(公告)号:WO2004087094A3
公开(公告)日:2004-11-25
申请号:PCT/CA2004000506
申请日:2004-04-02
Applicant: CELATOR TECHNOLOGIES INC , TARDI PAUL , HARASYM TROY , WEBB MURRAY , SHEW CLIFFORD
Inventor: TARDI PAUL , HARASYM TROY , WEBB MURRAY , SHEW CLIFFORD
CPC classification number: A61K9/127 , A61K9/1075 , A61K9/51 , A61K45/06
Abstract: Delivery vehicle compositions having stably associated therewith at least one therapeutic agent and at least one drug resistance modulator are useful in achieving a biologic effect to a drug resistance target.
Abstract translation: 具有与其稳定相关的至少一种治疗剂和至少一种耐药调节剂的递送载体组合物可用于实现对耐药靶标的生物学作用。
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公开(公告)号:WO03028697A3
公开(公告)日:2003-05-30
申请号:PCT/CA0201501
申请日:2002-10-03
Applicant: CELATOR TECHNOLOGIES INC , TARDI PAUL , JOHNSTONE SHARON , WEBB MURRAY , BALLY MARCEL , ABRAHAM SHEELA
Inventor: TARDI PAUL , JOHNSTONE SHARON , WEBB MURRAY , BALLY MARCEL , ABRAHAM SHEELA
IPC: A61K9/127 , A61K31/00 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K47/02 , A61K47/28 , A61P35/00 , A61P43/00 , A61K9/00 , A61K9/14
CPC classification number: A61K31/7072 , A61K9/127 , A61K9/1271 , A61K9/1272 , A61K31/00 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7076 , A61K33/24 , A61K45/06 , A61K2300/00
Abstract: This invention relates to encapsulation of drugs and other agents into liposomes.
Abstract translation: 本发明涉及将药物和其他试剂包封到脂质体中。
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7.LIPOSOMAL FORMULATIONS COMPRISING SECONDARY AND TERTIARY AMINES AND METHODS FOR PREPARING THEREOF 审中-公开
Title translation: 包含二级胺和三级胺的脂质体制剂及其制备方法公开(公告)号:WO2007076117A2
公开(公告)日:2007-07-05
申请号:PCT/US2006/049245
申请日:2006-12-22
Applicant: CELATOR PHARMACEUTICALS, INC. , DICKO, Awa , TARDI, Paul , MAYER, Lawrence , JOHNSTONE, Sharon
Inventor: DICKO, Awa , TARDI, Paul , MAYER, Lawrence , JOHNSTONE, Sharon
IPC: C12Q1/68
CPC classification number: A61K9/1278
Abstract: Provided herein are liposomal compositions comprising a therapeutic agent having a protonatable amino group and a secondary or tertiary amine, and methods for encapsulating such therapeutic agents. In one aspect, the present invention relates to liposomal formulations comprising irinotecan in a triethanolamine solution, and optionally comprising copper gluconate, and methods for preparing the same.
Abstract translation: 本文提供了包含具有可质子化氨基和仲胺或叔胺的治疗剂的脂质体组合物,以及用于包封这些治疗剂的方法。 在一个方面,本发明涉及包含伊立替康在三乙醇胺溶液中并且任选地包含葡糖酸铜的脂质体制剂及其制备方法。 p>
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8.
公开(公告)号:WO2006055903A1
公开(公告)日:2006-05-26
申请号:PCT/US2005/042131
申请日:2005-11-18
Applicant: CELATOR PHARMACEUTICALS, INC. , TARDI, Paul , WEBB, Murray , JOHNSTONE, Sharon , HARVIE, Pierrot , MAYER, Lawrence
Inventor: TARDI, Paul , WEBB, Murray , JOHNSTONE, Sharon , HARVIE, Pierrot , MAYER, Lawrence
IPC: A61K9/127
CPC classification number: A61K9/127 , A61K9/1278
Abstract: This invention relates to encapsulation of drugs and other agents into preformed delivery vehicles.
Abstract translation: 本发明涉及将药物和其他药剂包封到预先形成的运载工具中。 p> p>
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9.COMBINATION FORMULATIONS OF PLATINUM AGENTS AND FLUOROPYRIMIDINES 审中-公开
Title translation: 白蛋白剂和氟代嘧啶的组合制剂公开(公告)号:WO2004087105A8
公开(公告)日:2005-03-10
申请号:PCT/CA2004000508
申请日:2004-04-02
Applicant: CELATOR TECHNOLOGIES INC , MAYER LAWRENCE , BALLY MARCEL , WEBB MURRAY , TARDI PAUL , SHEW CLIFFORD
Inventor: MAYER LAWRENCE , BALLY MARCEL , WEBB MURRAY , TARDI PAUL , SHEW CLIFFORD
IPC: A61K9/127 , A61K33/24 , A61K45/06 , A61K31/282 , A61K31/513 , A61K31/7068 , A61K31/7072
CPC classification number: A61K9/127 , A61K9/1271 , A61K33/24 , A61K45/06 , A61K2300/00
Abstract: Compositions which comprise liposomes having stably associated therewith a platinum agent and an antimetabolite are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered.
Abstract translation: 包含与铂剂和抗代谢物稳定相关的脂质体的组合物在施用这些药物的组合时可用于获得增强的治疗效果。
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公开(公告)号:WO2004087115A3
公开(公告)日:2004-10-14
申请号:PCT/CA2004/000507
申请日:2004-04-02
Applicant: CELATOR TECHNOLOGIES INC. , MAYER, Lawrence , BALLY, Marcel , WEBB, Murray , TARDI, Paul , JOHNSTONE, Sharon
Inventor: MAYER, Lawrence , BALLY, Marcel , WEBB, Murray , TARDI, Paul , JOHNSTONE, Sharon
IPC: A61K9/127
Abstract: Compositions which comprise liposomes having stably associated therewith a camptothecin and a fluoropyrimidine are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered.
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