-
公开(公告)号:WO2021046467A1
公开(公告)日:2021-03-11
申请号:PCT/US2020/049565
申请日:2020-09-04
发明人: AZIZGOLSHANI, Hesham , COPPETA, Jonathan , CHAREST, Joseph L. , ZOM, Alex M. , BALDWIN, Keith B.
摘要: This disclosure provides systems and methods for integrating an array of electronic sensors capable of performing trans-epithelial electrical resistance (TEER) measurements into a microfluidic device that includes a well plate. In some implementations, the sensors can include electrodes that are submerged into fluidically connected wells of the microfluidic device, which can contain an electrically conductive fluid such as the cell culture media or a buffered salt solution. An array of such electrodes can be integrated into a lid of the system that includes the microfluidic device. These electrodes can be routed using a printed circuit board through a number of multiplex switches that can allow addressing of a desired unit of the device through a microprocessor in communication with a computer.
-
公开(公告)号:WO2020086951A1
公开(公告)日:2020-04-30
申请号:PCT/US2019/058038
申请日:2019-10-25
发明人: MOEBIUS, Michael G. , SPECTOR, Steven J. , BYRNES, Steven J. , BESSETTE, Christopher , LENNOX, Scott Evan , SINCLAIR, Matthew A. , ROGOMENTICH, Francis J.
摘要: A LiDAR system includes an array of optical emitters, an objective lens optically coupling each optical emitter to a respective unique portion of a field of view, an optical switching network coupled between a laser and the array of optical emitters and a controller coupled to the optical switching network and configured to cause the optical switching network to route light from the laser to a sequence of the optical emitters according to a dynamically varying temporal pattern and to vary the temporal pattern in a way that reduces risk of eye injury from the laser light.
-
公开(公告)号:WO2020056380A1
公开(公告)日:2020-03-19
申请号:PCT/US2019/051183
申请日:2019-09-13
摘要: Current technologies allow a robot to acquire a tool only if the tool is in a set known location, such as in a rack. In an embodiment, a method and corresponding system, can determine the previously unknown pose of a tool freely placed in an environment. The method can then calculate a trajectory that allows for a robot to move from its current position to the tool and attach with the tool. In such a way, tools can be located and used by a robot when placed at any location in an environment.
-
公开(公告)号:WO2020056377A1
公开(公告)日:2020-03-19
申请号:PCT/US2019/051180
申请日:2019-09-13
摘要: In an embodiment, a method for handling an order includes determining a plurality of ingredients based on an order, received from a user over a network, for a location having a plurality of robots. The method further includes planning at least one trajectory for at least one robot based on the plurality of ingredients and utensils available at the location, and proximity of each ingredient and utensil to the at least one robot. Each trajectory can be configured to move one of the plurality of ingredients into a container associated with the order. In an embodiment, the method includes executing the at least one trajectory by the at least one robot to fulfill the order. In an embodiment, the method includes moving the container to a pickup area.
-
公开(公告)号:WO2020056376A1
公开(公告)日:2020-03-19
申请号:PCT/US2019/051179
申请日:2019-09-13
发明人: CHU, Cody , TAYOUN, Anthony , JOHNSON, David, M.S. , ROONEY, Justin , WAGNER, Syler , LINES, Steven
摘要: An adaptor (200) comprising an element having a first interface component (404) and second interface component (415) wherein the first interface component (404) is configured to removably mate with a connector (112) of a robot (110) and the second interface component (415) is configured to attach to a tool (108).
-
公开(公告)号:WO2020056373A1
公开(公告)日:2020-03-19
申请号:PCT/US2019/051175
申请日:2019-09-13
IPC分类号: B25J9/16
摘要: Embodiments provide methods and systems to modify motion of a robot based on sound and context. An embodiment detects a sound in an environment and processes the sound. The processing includes comparing the detected sound to a library of sound characteristics associated with sound cues and/or extracting features or characteristics from the detected sound using a model. Motion of a robot is modified based on a context of the robot and at least one of: (i) the comparison, (ii) the features extracted from the detected sound, and (iii) the characteristics extracted from the detected sound.
-
公开(公告)号:WO2020056362A1
公开(公告)日:2020-03-19
申请号:PCT/US2019/051161
申请日:2019-09-13
发明人: CHU, Cody , TRUEBA, Luis , JOHNSON, David, M.S. , ROONEY, Justin
摘要: A problem with current food service robots is making the robots safe to work around food. A solution provided by the present disclosure is a food-safe tool switcher and corresponding tool. The tool switcher can mate with a variety of tools, which can be molded or 3D printed out of food-safe materials into a single-part, instead of constructed modularly. This provides for easier cleaning.
-
公开(公告)号:WO2020056279A1
公开(公告)日:2020-03-19
申请号:PCT/US2019/051040
申请日:2019-09-13
摘要: In an embodiment, a method and system use various sensors to determine a shape of a collection of materials (e.g., foodstuffs). A controller can determine a trajectory which achieves the desired end-state, possibly chosen from a set of feasible, collision-free trajectories to execute, and a robot executes that trajectory. The robot, executing that trajectory, scoops, grabs, or otherwise acquires the desired amount of material from the collection of materials at a desired location. The robot then deposits the collected material in the desired receptacle at a specific location and orientation.
-
公开(公告)号:WO2020047504A2
公开(公告)日:2020-03-05
申请号:PCT/US2019/049210
申请日:2019-08-30
发明人: TANDON, Vishal , LISSANDRELLO, Charles A. , BALESTRINI, Jenna L. , COPPETA, Jonathan R. , SWIERK, Patricia A.
摘要: Transfer of genetic and other materials to cells is conducted in a hands-free, automated, high throughput, continuous process. A system using a microfluidic hydrodynamic sheath flow configuration includes arrangements for pushing cells from side streams containing a cell culture medium to a central stream containing an electroporation buffer. Electroporation can be conducted in an assembly in which two or more microfluidic channels are provided in a parallel configuration and in which various layers can be stacked together to form a laminate type structure.
-
公开(公告)号:WO2019226812A1
公开(公告)日:2019-11-28
申请号:PCT/US2019/033587
申请日:2019-05-22
发明人: ISENBERG, Brett C. , COPPETA, Jonathan R. , DUBAY, Ryan A. , SCADDEN, David T. , SHARDA, Azeem Sanjay
IPC分类号: C12N5/00 , C12N5/0789
摘要: The present disclosure describes a system, device and method for differentiating cells such as, for example, generating ex vivo common lymphoid progenitors (CLPs) from human hematopoietic stem cells (HSCs). The system and method can be fully automated requiring minimal touch input from a user. Once harvested, the CLPs can be transplanted into a patient for cellular immune therapy.
-
-
-
-
-
-
-
-
-