公开(公告)号：WO1992008785A1

公开(公告)日：1992-05-29

申请号：PCT/AU1991000519

申请日：1991-11-14

Applicant: THE UNIVERSITY COMPANY PTY. LTD. ,  COOK, Robert, David

Inventor： THE UNIVERSITY COMPANY PTY. LTD.

IPC: C12N07/00

CPC classification number: C07K16/1027 ,  A61K39/12 ,  A61K39/155 ,  A61K2039/55566 ,  A61K2039/58 ,  C12N7/00 ,  C12N2760/18421 ,  C12N2760/18434 ,  G01N33/56983

Abstract: A morbillivirus, multiple sclerosis virus (MSV), is isolated from multiple sclerosis (MS) brain tissue. Antibodies which recognize or bind to MSV are used in diagnosis or treatment of MS. Serological diagnosis of MS comprises detection of circulating anti-MSV antibodies. Compositions and methods for producing an immune response against MS are also disclosed.

Abstract translation: 从多发性硬化（MS）脑组织中分离出流行病毒，多发性硬化病毒（MSV）。 识别或结合MSV的抗体用于MS的诊断或治疗。 MS的血清学诊断包括循环抗MSV抗体的检测。 还公开了用于产生针对MS的免疫应答的组合物和方法。