公开(公告)号：WO2023014933A2

公开(公告)日：2023-02-09

申请号：PCT/US2022/039507

申请日：2022-08-05

申请人： IMMUNIS.AI, INC. ,  KASSIS, Amin ,  ERICKSON, Geoffrey ,  WOJNO, Kirk ,  VAN NESTE, Leander ,  HENAO, Ricardo ,  STYLLI, Harry

发明人： KASSIS, Amin ,  ERICKSON, Geoffrey ,  WOJNO, Kirk ,  VAN NESTE, Leander ,  HENAO, Ricardo ,  STYLLI, Harry

IPC分类号： C12Q1/68 ,  C12Q1/6886 ,  C07K1/13 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N2800/52 ,  G01N2800/56 ,  G01N33/5047 ,  G01N33/56972 ,  G01N33/57434

摘要： The present disclosure relates to compositions and methods for assessing prostate cancer (e.g., identification of the aggressiveness or indolence of prostate cancer) in a subject. The compositions and methods include obtaining subject specific information (e.g., age, digital rectal exam (DRE) data, prostate volume, prostate density, total prostate-specific antigen (PSA)) and obtaining a biological sample from a subject and determining a measurement for a panel of biomarkers in the biological sample. Compositions and methods of the disclosure find use in both clinical and research settings, for example, within the fields of biology, immunology, medicine, and oncology.