公开(公告)号：WO2018152544A1

公开(公告)日：2018-08-23

申请号：PCT/US2018/018848

申请日：2018-02-20

Applicant: MARVELL WORLD TRADE LTD. ,  SHU, Biing, Long ,  MENG, Dehuan ,  WALSH, Hugh ,  WU, Fei

Inventor： SHU, Biing, Long ,  MENG, Dehuan ,  WALSH, Hugh ,  WU, Fei

IPC: H04L12/40 ,  H04L12/24 ,  G06F17/40

Abstract: Embodiments described herein provide a method for an error logging mechanism operated with controller area network (CAN) buses within an Ethernet network. A first interrupt request indicative of a first error condition that occurs at the first CAN bus is received at an Ethernet bridge and from a first CAN controller connected to a first CAN bus. In response to the first interrupt request, the first interrupt request is serviced by retrieving, from a first error register at the first CAN controller, information relating to the first error condition. The information relating to the first error condition is encapsulated in a first frame in compliance with a layer 2 transport protocol for time-sensitive applications. The encapsulated first frame is then sent, via an Ethernet switch, to an error logging device installed at a location remote to the first CAN bus.

公开(公告)号：WO2017095874A1

公开(公告)日：2017-06-08

申请号：PCT/US2016/064136

申请日：2016-11-30

Applicant: MARVELL WORLD TRADE LTD. ,  MENG, Dehuan ,  SHU, Biing Long ,  WALSH, Hugh ,  WU, Fei

Inventor： MENG, Dehuan ,  SHU, Biing Long ,  WALSH, Hugh ,  WU, Fei

IPC: H04L12/40 ,  H04L12/46

CPC classification number: H04L45/745 ,  H04L12/40 ,  H04L12/40143 ,  H04L12/40163 ,  H04L12/4625 ,  H04L12/4633 ,  H04L12/4662 ,  H04L12/66 ,  H04L43/106 ,  H04L45/021 ,  H04L45/16 ,  H04L45/54 ,  H04L47/28 ,  H04L2012/40215

Abstract: Systems and methods are provided for routing a message in a network. A bit length of an identifier field of a received message is identified. A lookup table is selected based on the bit length of the identifier field. The identifier field is used as a reference for the lookup table to identify a bus for the message, and the message is forwarded to the bus.

Abstract translation: 提供用于在网络中路由消息的系统和方法。 识别接收到的消息的标识符字段的比特长度。 基于标识符字段的位长来选择查找表。 标识符字段用作查找表的参考，以标识消息的总线，并且消息被转发到总线。

公开(公告)号：WO2012129758A1

公开(公告)日：2012-10-04

申请号：PCT/CN2011/072155

申请日：2011-03-25

Applicant: BIOMERIEUX ,  YE, Xun ,  WU, Fei ,  XU, Qinghua ,  LIU, Fang ,  MENG, Xia ,  MOUGIN, Bruno

Inventor： YE, Xun ,  WU, Fei ,  XU, Qinghua ,  LIU, Fang ,  MENG, Xia ,  MOUGIN, Bruno

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/158

Abstract: The present invention discloses a method for determining in vitro, in a peripheral blood sample, the probability for an individual to suffer from a colorectal cancer, using the comparison of the amount of expression products of nucleic acids of genes of the individual to be tested with the amount of expression products of nucleic acids of the same genes obtained from a CRC group of patients constituting the positive control and with the same genes obtained from a CNC group of individuals constituting the negative control; and a kit comprising specific binding partners for the expression products.

Abstract translation: 本发明公开了一种用于在外周血样品中测定个体遭受结肠直肠癌的可能性的方法，该方法使用待测个体的基因核酸的表达产物的量与 从构成阳性对照的CRC组的患者获得的相同基因的核酸的表达产物的量和从构成阴性对照的个体的CNC组获得的相同基因的表达产物的量; 以及包含用于表达产物的特异性结合伴侣的试剂盒。

公开(公告)号：WO2011153684A1

公开(公告)日：2011-12-15

申请号：PCT/CN2010/073659

申请日：2010-06-08

Applicant: BIOMERIEUX ,  YE, Xun ,  WU, Fei ,  XU, Qinghua ,  LIU, Fang ,  MENG, Xia ,  MOUGIN, Bruno

Inventor： YE, Xun ,  WU, Fei ,  XU, Qinghua ,  LIU, Fang ,  MENG, Xia ,  MOUGIN, Bruno

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/172

Abstract: The present invention discloses a method and kit for the prognosis of colorectal cancer, especially a method comprising: a) obtaining the peripheral blood sample and extracting total RNA from the blood sample, b) contacting the total RNA with at least one reagent that is specific for at least one NK cell gene and no more than 25 specific reagents for 25 NK cell genes, c) determining the expression level of the at least one NK cell gene and of the most 25 NK cell genes to obtain an expression profile for the patient, and d) performing analysis of the expression profile of the patient.

Abstract translation: 本发明公开了一种用于预后结直肠癌的方法和试剂盒，特别是一种方法，包括：a）获得外周血样品并从血液样品中提取总RNA，b）使总RNA与至少一种特异性试剂 对于至少一种NK细胞基因，对于25个NK细胞基因不超过25种特异性试剂，c）确定至少一种NK细胞基因和最多25个NK细胞基因的表达水平以获得患者的表达谱 ，以及d）对患者的表达谱进行分析。

公开(公告)号：WO2011150976A1

公开(公告)日：2011-12-08

申请号：PCT/EP2010/057843

申请日：2010-06-04

Applicant: BIOMÉRIEUX ,  YE, Xun ,  WU, Fei ,  XU, Qinghua ,  MENG, Xia ,  MOUGIN, Bruno ,  LIU, Fang

Inventor： YE, Xun ,  WU, Fei ,  XU, Qinghua ,  MENG, Xia ,  MOUGIN, Bruno ,  LIU, Fang

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q1/6837 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C40B40/06

Abstract: The present invention relates to method and kit for the prognosis of colorectal cancer. Especially a method comprising: a) obtaining the peripheral blood sample and extracting total RNA from the blood sample, b) contacting the total RNA with at least one reagent that is specific for at least one NK cell gene and no more than 25 specific reagents for 25 NK cell genes, c) determining the expression level of the at least one NK cell gene and of the most 25 NK cell genes to obtain an expression profile for the patient, d) performing analysis of the expression profile of the patient with expression profiles of NK cell genes from patients previously clinically classified as a good prognosis and expression profiles of NK cell genes from patients previously classified as a poor prognosis, wherein - if the expression profile for the patient is clustered with the expression profiles from patients previously clinically classified as a poor prognosis, then the patient is determined to have a poor prognosis, and - if the expression profile for the patient is clustered with the expression profiles from patients previously clinically classified as a good prognosis, then the patient is determined to have a good prognosis.

Abstract translation: 本发明涉及结直肠癌预后的方法和试剂盒。 特别是一种方法，包括：a）获得外周血液样品并从血液样品中提取总RNA，b）使总RNA与至少一种对至少一种NK细胞基因特异性的试剂和不超过25种特异性试剂接触 25个NK细胞基因，c）确定至少一个NK细胞基因和最多25个NK细胞基因的表达水平以获得患者的表达谱，d）用表达谱分析患者的表达谱 来自先前临床分类为良好预后的患者的NK细胞基因的NK细胞基因和先前归类为不良预后的患者的NK细胞基因的表达谱，其中 - 如果患者的表达谱与来自先前临床分类为 预后不良，那么患者的预后判定不佳，如果患者的表达谱与快速聚集 离子谱从先前临床分类为良好的预后，然后确定患者有良好的预后。

公开(公告)号：WO2010088299A1

公开(公告)日：2010-08-05

申请号：PCT/US2010/022274

申请日：2010-01-27

Applicant: GOOGLE INC. ,  WU, Fei ,  MADHAVAN, Jayant ,  HALEVY, Alon

Inventor： WU, Fei ,  MADHAVAN, Jayant ,  HALEVY, Alon

IPC: G06F17/30

CPC classification number: G06F17/30554 ,  G06F17/30528 ,  G06F17/3053 ,  G06F17/30672 ,  G06F17/30867

Abstract: Methods, systems, and apparatus, including computer program products, for generating aspects associated with entities. In some implementations, a method includes receiving data identifying an entity; generating a group of candidate aspects for the entity; modifying the group of candidate aspects to generate a group of modified candidate aspects comprising combining similar candidate aspects and grouping candidate aspects using one or more aspect classes each associated with one or more candidate aspects; ranking one or more modified candidate aspects in the group of modified candidate aspects based on a diversity score and a popularity score; and storing an association between one or more highest ranked modified candidate aspects and the entity. The aspects can be used to organize and present search results in response to queries for the entity.

Abstract translation: 用于生成与实体相关的方面的方法，系统和装置，包括计算机程序产品。 在一些实现中，一种方法包括接收识别实体的数据; 为该实体产生一组候选方面; 修改所述候选方面的组以生成一组修改的候选方面，其包括组合类似候选方面并使用与一个或多个候选方面相关联的一个或多个方面类别对候选方面分组; 基于多样性分数和受欢迎程度，对修改的候选方面组中的一个或多个修改后的候选方面进行排序; 以及存储一个或多个最高排名的修改候选方面与所述实体之间的关联。 这些方面可用于组织和呈现搜索结果以响应对实体的查询。

公开(公告)号：WO2013048786A1

公开(公告)日：2013-04-04

申请号：PCT/US2012/055501

申请日：2012-09-14

Applicant: APPLE INC. ,  GAMADIA, Mark, N. ,  WU, Fei ,  SHEN, Shizhe ,  RUKES, Jason

Inventor： GAMADIA, Mark, N. ,  WU, Fei ,  SHEN, Shizhe ,  RUKES, Jason

IPC: H04N17/00 ,  H04N1/00 ,  G01M11/02

CPC classification number: H04N17/002

Abstract: A test chart can be used to test sharpness performance of an imaging system's full image field by having a sharpness inspection area formed of a plurality of identical visual elements that abut each other leaving no gaps to thereby form a mosaic. Each visual element may be a plurality of groups of differently oriented contrasting lines. The mosaic may fill an entire image captured by an imager of the imaging system. Thus, a test system can image the chart to objectively assess the performance of the imaging system in terms of a certain level of image quality (e.g. sharpness, tilt, etc) throughout the entire spatial area of the captured image. The size of the chart and spatial frequency (e.g., spacing) of the visual element lines can be selected to test an imaging system's full field sharpness at selected spatial frequencies. The full field sharpness results can be used to more quickly and accurately determine different aspects of image quality from a given imaging system and its components.

Abstract translation: 可以使用测试图来通过具有由相互邻接的多个相同视觉元件形成的清晰度检查区域来测试成像系统的全图像场的锐度性能，而不产生间隙从而形成马赛克。 每个视觉元素可以是多组不同方向的对比线。 马赛克可以填充由成像系统的成像器捕获的整个图像。 因此，测试系统可以对图表进行成像，以客观地评估成像系统在拍摄图像的整个空间区域中的一定水平的图像质量（例如锐度，倾斜度等）方面的性能。 可以选择图表的尺寸和视觉元素线的空间频率（例如，间隔）以在选定的空间频率处测试成像系统的全场锐度。 可以使用全场锐度结果更快速和准确地确定给定成像系统及其组件的图像质量的不同方面。

公开(公告)号：WO2008141496A1

公开(公告)日：2008-11-27

申请号：PCT/CN2007/002962

申请日：2007-10-16

Applicant: JIN, Tuo ,  GENG, Yan ,  WU, Fei ,  YUAN, Weien

Inventor： JIN, Tuo ,  GENG, Yan ,  WU, Fei ,  YUAN, Weien

IPC: A61K9/16 ,  A61K38/18 ,  A61K38/19 ,  A61K47/34 ,  A61K47/36 ,  A61P9/04 ,  A61P35/00

CPC classification number: A61K47/36 ,  A61K9/1652 ,  A61K9/19 ,  A61K38/1816 ,  A61K38/193

Abstract: This patent disclosed sustained-release microsphere dosage forms of EPO and GM-CSF respectively and methods for their preparation. The proteins are first loaded in solvent-resistant polysaccharide particles using a stabilized aqueous-aqueous emulsion consisting of polysaccharide dispersed phase and polyethylene glycol (PEG) continuous phase, followed by freeze-drying. This particle forming process avoids exposing proteins to water-oil or water-air (or intra-particle cross-linking reagent), factors known to denature proteins. The lyophilized powder was then washed using organic solvent to remove the PEG continuous phase. The proteins loaded in the solvent-resistant polysaccharide particles can easily be sustained-release microsphere formulation without denaturing, aggregation, adsorption and deactivation.

Abstract translation: 该专利公开了EPO和GM-CSF的缓释微球剂形式及其制备方法。 首先使用由多糖分散相和聚乙二醇（PEG）连续相组成的稳定的水性乳液将蛋白质负载在耐溶剂的多糖颗粒中，然后冷冻干燥。 这种颗粒形成过程避免将蛋白质暴露于已知会使蛋白质变性的因素的水油或水 - 空气（或颗粒内交联试剂）中。 然后使用有机溶剂洗涤冻干的粉末以除去PEG连续相。 负载在耐溶剂的多糖颗粒中的蛋白质可以容易地是缓释微球制剂，而不变性，聚集，吸附和失活。

公开(公告)号：WO2007025441A1

公开(公告)日：2007-03-08

申请号：PCT/CN2006/001777

申请日：2006-07-20

Applicant: JIN, Tuo ,  WU, Fei ,  YUAN, Weien

Inventor： JIN, Tuo ,  WU, Fei ,  YUAN, Weien

IPC: A61K9/14 ,  A61K9/19 ,  A61K47/36 ,  A61K47/40 ,  A61K47/30 ,  A61K39/00 ,  A61K9/107

CPC classification number: A61K9/1694 ,  A61K9/0024 ,  A61K9/1623 ,  A61K9/1647 ,  A61K9/1652 ,  A61K9/19 ,  A61K9/7007 ,  A61K39/00 ,  A61L27/48 ,  A61L31/10 ,  A61L31/129

Abstract: A method of preparing polysaccharide glassy microparticles which are less than 10μm in diameter and contain structurally delicate agents, such as proteins, peptides, gene materials, vaccines, antibodies, viruses and liposomes using low-temperature aqueous-aqueous emulsification (free of polyelectrolytes) and freezing-induced phase separation. When delicate agents are added to a polysaccharide-PEG two phase system followed by homogenization (or other shear adding process), the agents partition into the polysaccharide dispersed phase preferentially. These processes help to avoid aggregation of proteins caused by interaction with charged polyelectrolytes used for stabilizing the polysaccharide dispersed phase in our previously reported aqueous-aqueous emulsion. When this system is frozen and lyophilized, glassy particles less than 10μm in diameter containing delicate agents can be formed. These fine polysaccharide particles protect proteins within their hydrophilic glassy matrix, and can therefore be easily suspended in hydrophobic polymer solutions and formulated to various forms of sustained release devices such as microsphere, sheets, fibers, coating layers, and scaffolds. The particles can also be dispersed in hydrophilic gels to improve releasing kinetics and to deliver vaccines and antibodies for immune therapy.

Abstract translation: 制备直径小于10μm并含有结构上细腻的试剂如蛋白质，肽，基因材料，疫苗，抗体，病毒和脂质体的多糖玻璃状微粒的方法，该方法使用低温水性乳化（无聚电解质）和 冷冻诱导相分离。 当将精制剂加入到多糖-PEG两相体系中，随后进行均质化（或其他剪切加料法）时，试剂优先分配到多糖分散相中。 这些过程有助于避免与我们以前报道的水性乳液中稳定多糖分散相的带电聚电解质相互作用引起的蛋白质聚集。 当该系统被冷冻和冻干时，可以形成直径小于10μm的含有精细剂的玻璃状颗粒。 这些细多糖颗粒保护其亲水性玻璃质基质内的蛋白质，因此可以容易地悬浮在疏水性聚合物溶液中并配制成各种形式的缓释装置，例如微球，片，纤维，涂层和支架。 颗粒也可以分散在亲水性凝胶中，以改善释放动力学和递送用于免疫治疗的疫苗和抗体。

公开(公告)号：WO2017095907A1

公开(公告)日：2017-06-08

申请号：PCT/US2016/064192

申请日：2016-11-30

Applicant: MARVELL WORLD TRADE LTD. ,  WU, Fei ,  MENG, Dehuan ,  SHU, Biing, Long ,  WALSH, Hugh

Inventor： WU, Fei ,  MENG, Dehuan ,  SHU, Biing, Long ,  WALSH, Hugh

IPC: H04L12/40 ,  H04L12/46

CPC classification number: H04L45/745 ,  H04L12/40 ,  H04L12/40143 ,  H04L12/40163 ,  H04L12/4625 ,  H04L12/4633 ,  H04L12/4662 ,  H04L12/66 ,  H04L43/106 ,  H04L45/021 ,  H04L45/16 ,  H04L45/54 ,  H04L47/28 ,  H04L2012/40215

Abstract: Systems, methods, and apparatuses are described herein for implementing a switched Controller Area Network ("CAN"). In some embodiments, control circuitry of a bridge may receive a CAN message. The control circuitry may identify a first plurality of nodes to which the CAN message is addressed by comparing a virtual CAN bus identifier of the CAN message to entries of a virtual CAN bus lookup table, and may identify a second plurality of nodes to which the CAN message is addressed by comparing a message identifier ("ID") of the CAN message to entries of a message ID lookup table. The control circuitry may perform a logical AND operation between the first plurality of nodes and the second plurality of nodes, and may transmit the CAN message to a node that satisfies the logical AND operation.

Abstract translation: 这里描述了用于实现开关控制器区域网络（“CAN”）的系统，方法和装置。 在一些实施例中，桥的控制电路可以接收CAN消息。 控制电路可以通过将CAN消息的虚拟CAN总线标识符与虚拟CAN总线查找表的条目进行比较来标识CAN消息被寻址到的第一多个节点，并且可以标识CAN的第二多个节点 消息通过将CAN消息的消息标识符（“ID”）与消息ID查找表的条目进行比较来寻址。 控制电路可以执行第一多个节点和第二多个节点之间的逻辑“与”操作，并且可以将CAN消息发送到满足逻辑与操作的节点。