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公开(公告)号：WO2009152777A1
公开(公告)日：2009-12-23
申请号：PCT/CN2009/072352
申请日：2009-06-19
CPC classification number: A61K9/703 , A61K9/7053 , A61K9/7061 , A61K9/7069 , A61K9/7084
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公开(公告)号：WO2012072014A1
公开(公告)日：2012-06-07
申请号：PCT/CN2011/083040
申请日：2011-11-28
IPC: A61K9/70 , A61K31/135 , A61K47/32 , A61K47/34 , A61P25/00
CPC classification number: A61K9/7061 , A61K31/135
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公开(公告)号：WO2011050728A1
公开(公告)日：2011-05-05
申请号：PCT/CN2010/078189
申请日：2010-10-28
Applicant: 重庆医药工业研究院有限责任公司 , 林佳亮 , 邓杰 , 陈皓 , 张涛
CPC classification number: A61K31/135 , A61K9/0014 , A61K9/06 , A61K9/7061 , A61K9/7069 , A61K31/355 , A61K31/375 , A61K47/10 , A61K47/22 , A61K2300/00
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公开(公告)号：WO2007101400A1
公开(公告)日：2007-09-13
申请号：PCT/CN2007/000713
申请日：2007-03-06
Applicant: 重庆医药工业研究院有限责任公司 , 上海复星医药(集团)股份有限公司 , 林佳亮 , 肖进迈 , 邓杰
IPC: A61K9/70 , A61K47/30 , A61K31/135 , A61P25/00
CPC classification number: A61K31/135 , A61K9/7053 , A61K9/7061 , A61K9/7069 , A61K9/7092
Abstract: A transdermal patch of rasagiline for treatment or prophylaxis of nervous system disease and its preparation process, comprises: a backing layer inert to the components of the matrix a matrix layer contg. rasagiline and its or its salt, and a removable protective layer, characterised in that the matrix is an adhesive system having distribured therein as polymer and organic or inorganic bulking agent and dermal penetration enhancer, the reservoir in the matrix layer contains rasagiline, said polymer is based on organic macromolecular material and useful as the active substance reservoir and adhesive.
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