公开(公告)号：WO2020201458A1

公开(公告)日：2020-10-08

申请号：PCT/EP2020/059460

申请日：2020-04-02

Applicant: 4D PHARMA CORK LIMITED

Inventor： O'TOOLE, Paul ,  SHANAHAN, Fergus ,  JEFFERY, Ian ,  O'HERLIHY, Eileen ,  DAS, Anubhav

IPC: C12Q1/689 ,  C12Q1/04

Abstract: The application provides new and improved methods for diagnosing BAM.

公开(公告)号：WO2020201457A1

公开(公告)日：2020-10-08

申请号：PCT/EP2020/059459

申请日：2020-04-02

Applicant: 4D PHARMA CORK LIMITED

Inventor： O'TOOLE, Paul ,  SHANAHAN, Fergus ,  JEFFERY, Ian ,  O'HERLIHY, Eileen ,  DAS, Anubhav

IPC: C12Q1/689 ,  C12Q1/04

Abstract: The application provides new and improved methods for diagnosing IBS.

公开(公告)号：WO2022058552A1

公开(公告)日：2022-03-24

申请号：PCT/EP2021/075705

申请日：2021-09-17

Applicant: 4D PHARMA CORK LIMITED

Inventor： O'TOOLE, Paul ,  SHANAHAN, Fergus ,  JEFFERY, Ian

IPC: C12Q1/6883 ,  C12Q1/70

Abstract: The invention provides a method for diagnosing irritable bowel syndrome (IBS) in a patient, the method comprising: (a) analysing the viral content of a gastrointestinal sample, such as a faecal sample, obtained from the patient; (b) calculating the gastrointestinal virome diversity of the patient on the basis of said analysing in (a); (c) comparing the gastrointestinal virome diversity of the patient calculated in (b) to the gastrointestinal virome diversity of a control population of one or more further patients; wherein if the gastrointestinal virome diversity of the patient is less than the gastrointestinal virome diversity of the control population, the patient is diagnosed as having IBS.