公开(公告)号：WO2022232834A1

公开(公告)日：2022-11-03

申请号：PCT/US2022/072008

申请日：2022-04-29

Applicant: ABBVIE INC.

Inventor： PHILLIPS, Andrew C. ,  REILLY, Regina M. ,  DOHERTY, George A. ,  JI, Cheng ,  BRUNCKO, Milan ,  BOGHAERT, Erwin R. ,  ANDERSON, Mark

IPC: C07K16/28 ,  A61K47/68 ,  C07D491/22 ,  C07D317/44 ,  C07D317/70

Abstract: The present disclosure provides c-Met antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.

公开(公告)号：WO2017214322A4

公开(公告)日：2017-12-14

申请号：PCT/US2017/036428

申请日：2017-06-07

Applicant: ABBVIE INC.

Inventor： BENATUIL, Lorenzo ,  BRUNCKO, Milan ,  CHAO, Debra ,  DOHERTY, George ,  FREY, Robin R. ,  IZERADJENE, Kamel ,  JUDD, Andrew S. ,  PHILLIPS, Andrew C. ,  SONG, Xiaohong ,  SOUERS, Andrew J. ,  SULLIVAN, Gerard M. ,  TAO, Zhi-Fu ,  THAKUR, Archana

IPC: C07K16/28 ,  A61K47/68 ,  A61K31/337 ,  A61K39/00 ,  A61P35/00

Abstract: The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

公开(公告)号：WO2017214322A1

公开(公告)日：2017-12-14

申请号：PCT/US2017/036428

申请日：2017-06-07

Applicant: ABBVIE INC.

Inventor： BENATUIL, Lorenzo ,  BRUNCKO, Milan ,  CHAO, Debra ,  DOHERTY, George ,  FREY, Robin R. ,  IZERADJENE, Kamel ,  JUDD, Andrew S. ,  PHILLIPS, Andrew C. ,  SONG, Xiaohong ,  SOUERS, Andrew J. ,  SULLIVAN, Gerard M. ,  TAO, Zhi-Fu ,  THAKUR, Archana

IPC: C07K16/28 ,  A61K47/68 ,  A61K31/337 ,  A61K39/00 ,  A61P35/00

Abstract: The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Abstract translation: 本发明涉及B7同源3蛋白（B7-H3）抗体和抗体药物缀合物（ADC），包括使用所述抗体和ADC的组合物和方法。