公开(公告)号：WO2014017986A1

公开(公告)日：2014-01-30

申请号：PCT/SG2013/000311

申请日：2013-07-26

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： PEH, Ruey Feng ,  CHEW, Jing Ming ,  LOKE, Wei Ling Fiona ,  TAY, Hsien Ts'ung

IPC: A61M5/158

CPC classification number: A61M5/3273 ,  A61B17/0057 ,  A61B17/06114 ,  A61B17/132 ,  A61B18/1477 ,  A61B90/39 ,  A61B90/80 ,  A61B2017/00004 ,  A61B2017/00526 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2018/00577 ,  A61B2090/062 ,  A61B2090/3962 ,  A61M1/3653 ,  A61M1/3659 ,  A61M5/158 ,  A61M5/3286 ,  A61M5/3287 ,  A61M5/329 ,  A61M39/0208 ,  A61M39/0247 ,  F04C2270/0421

Abstract: According to various embodiments, a method and system to obtain access to a blood vessel underneath a skin layer that may preserve lifespan of the blood vessel and reduce executional skill variability may be provided. The method includes placing a guiding portion between the blood vessel and the skin layer; and configuring the guiding portion to receive and guide a needle to reach the same location of the blood vessel repeatedly and consistently; and forming a resultant scarred track between the blood vessel and the skin layer as the guiding portion is resorbed over time. The system includes a vascular access device configurable to first possess strength to penetrate through a tissue layer, subsequently possess flexibility to conform to the surrounding tissue beneath the tissue layer; and a guiding portion which may be resorbable, wherein the inlet includes a larger diameter compared to the outlet.

Abstract translation: 根据各种实施例，可以提供一种方法和系统，用于获得对皮肤层下方的血管的通路，其可以保持血管的寿命并降低执行技能的变异性。 该方法包括在血管和皮肤层之间放置引导部分; 以及构造所述引导部分以重复且一致地接收和引导针头到达所述血管的相同位置; 并且随着引导部分随着时间的推移而吸收，在血管和皮肤层之间形成由此引起的伤痕痕迹。 该系统包括可配置为首先具有穿透组织层的强度的血管通路装置，随后具有柔性以适应组织层下方的周围组织; 以及可再吸收的引导部分，其中所述入口与所述出口相比具有较大的直径。

公开(公告)号：WO2016111650A1

公开(公告)日：2016-07-14

申请号：PCT/SG2016/050007

申请日：2016-01-07

Applicant: AGENCY FOR SCIENCE,TECHNOLOGY AND RESEARCH ,  SINGAPORE HEALTH SERVICES PTE LTD

Inventor： PEH, Ruey Feng ,  LIM, Soo Ghim ,  KUAN, Yee Han ,  TOH, Yanling ,  TAY, Hsien Ts'ung ,  TAN, Seck Guan

IPC: A61M5/158 ,  A61M39/02

CPC classification number: A61M1/3653 ,  A61M1/3655 ,  A61M1/3659 ,  A61M39/0208 ,  A61M39/0247 ,  A61M2039/0273

Abstract: A subcutaneous implantable device for guiding a vascular access member, the device including a channel defined by a through-hole in the device, wherein the channel is configured to guide the vascular access member there-through to a vascular site; and anchoring means adapted for fixedly attaching, in a form of using suture, tissue ingrowth, tissue encapsulation or tissue adhesion, the device io at least one of a dermis or a subcutaneous tissue at a position underneath the dermis to allow repeated access of the vascular access member through the channel to the vascular site, wherein the device is dimensioned to allow the device to be attached through the anchoring means for anchoring the entire device at a distance away from the vascular site, A method of creating scar tissue track for vascular access is also disclosed where the subcutaneous implantable device for guiding vascular access member is first implanted sub-dermally, the dermis is palpated to feel for the device location and orientation, the guiding channel is accessed using the sharp vascular access member and following the angle of the guiding channel to access the vascular site and repeating the steps till scarred tissue track is created and finally, switching the sharp vascular access member to a blunt vascular access member to access the vascular site via the scarred tissue track.

Abstract translation: 一种用于引导血管通路构件的皮下可植入装置，所述装置包括由所述装置中的通孔限定的通道，其中所述通道构造成将所述血管通路构件引导到血管部位; 以及锚固装置，其适于以使用缝合线的形式固定地附接组织向内生长，组织包封或组织粘附，所述装置在真皮下面的位置处的真皮或皮下组织中的至少一个，以允许血管的重复进入 通过所述通道进入所述血管部位，其中所述装置的尺寸被设计成允许所述装置通过所述锚固装置附接，用于在远离所述血管部位的距离处锚定整个装置。创建用于血管通路的瘢痕组织轨迹的方法 还公开了用于引导血管通路构件的皮下可植入装置首先被皮下植入，触摸皮肤以感觉到装置的位置和取向，导引通道使用尖锐的血管通路构件接近并沿着 引导通道进入血管部位并重复步骤，直到形成瘢痕组织轨迹，最后切换sh arp血管通路构件到平坦的血管通路构件，以通过瘢痕组织轨道进入血管部位。

公开(公告)号：WO2016111642A1

公开(公告)日：2016-07-14

申请号：PCT/SG2015/050508

申请日：2015-12-28

Applicant: AGENCY FOR SCIENCE,TECHNOLOGY AND RESEARCH

Inventor： LIM, Soo Ghim ,  PEH, Ruey Feng ,  KUAN, Yee Han ,  TOH, Yanling

IPC: A61B17/00 ,  A61M31/00 ,  A61M37/00

CPC classification number: A61B17/062 ,  A61B17/0482 ,  A61B17/3468 ,  A61B2017/00115 ,  A61B2017/00876 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2090/0811 ,  A61M1/3653 ,  A61M1/3655 ,  A61M25/06

Abstract: According to embodiments of the present invention, a subcutaneous implant delivery apparatus is provided. The apparatus includes a receiving portion configured to receive a subcutaneous implantable device; and a stabilizing portion configured to cooperate with the receiving portion to hold the subcutaneous implantable device in a fixed position. The receiving portion and the stabilizing portion are movable relative to each other between a released configuration, wherein the receiving portion and the stabilizing portion are configured to move apart from each other to allow the receiving portion to be inserted under a skin layer, and a closed configuration, wherein the receiving portion and the stabilizing portion are configured to move toward each other to allow the subcutaneous implantable device to be held adjacent to the skin layer. According to further embodiments of the present invention, a method of delivering a subcutaneous implantable device for accessing a vascular site is also provided.

Abstract translation: 根据本发明的实施例，提供了一种皮下植入物输送装置。 该装置包括被配置为接收皮下可植入装置的接收部分; 以及稳定部，其构造成与所述接收部配合以将所述皮下可植入装置保持在固定位置。 接收部分和稳定部分可在释放构造之间相对于彼此移动，其中接收部分和稳定部分被构造成彼此分开移动以允许接收部分插入皮肤层下面，并且闭合 配置，其中所述接收部分和所述稳定部分被配置成朝向彼此移动，以允许所述皮下可植入装置被保持在所述皮肤层附近。 根据本发明的另外的实施例，还提供了一种输送用于进入血管部位的皮下可植入装置的方法。