公开(公告)号：WO2022056278A1

公开(公告)日：2022-03-17

申请号：PCT/US2021/049890

申请日：2021-09-10

Applicant: ALEXION PHARMACEUTICALS, INC.

Inventor： POTTER, David George ,  DZIELAWA, Jennifer Ann ,  CARTER, Brenda Sue ,  MA, Mark

IPC: A61K39/395 ,  C07K16/38 ,  C12Q1/26 ,  G01N33/84

Abstract: Provided herein are antibodies which bind to ceruloplasmin and are useful for various applications, including detecting ceruloplasmin and immunocapturing ceruloplasmin in biological samples. The antibodies are useful in methods of measuring non-ceruloplasmin-bound copper concentrations and labile-bound copper concentrations in biological samples.