公开(公告)号：WO2022246055A1

公开(公告)日：2022-11-24

申请号：PCT/US2022/030014

申请日：2022-05-19

Applicant: AMGEN INC.

Inventor： GOSWAMI, Devrishi ,  ZHANG, Jun ,  PIEDMONTE, Deirdre ,  PADMAKUMAR, Vikashni ,  LE, David ,  SANTOS, Maria, Raquel ,  QI, Wei

IPC: B65B3/00

Abstract: A method of filling a vial. The method includes providing a pump corresponding to a vial and setting a drip retraction parameter for the pump to any value equal to or less than 20 degrees. The method also includes setting a no adjustment limit for a fill weight of the vial to T1, with T1 being at or in a range of about 2% more or less than a fill weight of a target fill weight T0, wherein a process performance index Cpk (Cpk) for the vial throughout a fill cycle exceeds a minimum value.