公开(公告)号：WO2017140774A1

公开(公告)日：2017-08-24

申请号：PCT/EP2017/053492

申请日：2017-02-16

Applicant: BASF SE

Inventor： RIEDEL, Dominic ,  TELES, Joaquim H. ,  SCHELLING, Heiner ,  WEGERLE, Ulrike ,  MÜLLER, Ulrich ,  PARVULESCU, Andrei-Nicolae ,  MANNWEILER, Jochen ,  HENN, Timo ,  LÜDERITZ, Thomas ,  WÖRZ, Nicolai Tonio ,  MÜLLER, Christian ,  WEBER, Markus ,  URBANCZYK, Daniel

IPC: C07D301/12 ,  C07D301/36

CPC classification number: C07D301/12 ,  C07D301/36

Abstract: A continuous process for the preparation of propylene oxide, comprising a start-up stage and normal run stage, wherein the normal run stage comprises (i) continuously providing a liquid feed stream comprising propene, hydrogen peroxide, acetonitrile, a formate salt, water and optionally propane, wherein in the liquid feed stream, the molar amount of the formate salt relative to the molar amount of hydrogen peroxide at a given point of time during the normal run stage is a N (Fo/H 2 O 2 ); (ii) continuously passing the liquid feed stream provided in (i) into an epoxidation zone comprising a catalyst comprising a titanium zeolite having framework type MWW, and subjecting the liquid feed stream to epoxidation reaction conditions in the epoxidation zone, obtaining a reaction mixture comprising propylene oxide, acetonitrile, water, the formate salt, optionally propene, and optionally propane; (iii) continuously removing an effluent stream from the epoxidation zone, the effluent stream comprising propylene oxide, acetonitrile, water, at least a portion of the formate salt, optionally propene, and optionally propane; wherein the normal run stage is characterized in an average rate of change of a N (Fo/H 2 O 2 ) of less than 0 h -1 .

Abstract translation: 一种用于制备环氧丙烷的连续方法，其包括启动阶段和正常运行阶段，其中正常运行阶段包括（i）连续提供包含丙烯，过氧化氢， 乙腈，甲酸盐，水和任选的丙烷，其中在液体进料流中，相对于在正常运行阶段期间的给定时间点的过氧化氢的摩尔量，甲酸盐的摩尔量是N （F0 / H <子> 2 0 <子> 2 ）; （ii）将（i）中提供的液体进料流连续通入包含催化剂的环氧化区中，所述催化剂包含具有骨架型MWW的钛沸石，并使液体进料流在环氧化区中经受环氧化反应条件，获得反应混合物，所述反应混合物包含 环氧丙烷，乙腈，水，甲酸盐，任选的丙烯和任选的丙烷; （iii）连续地从环氧化区中除去流出物流，所述流出物流包含环氧丙烷，乙腈，水，至少一部分甲酸盐，任选的丙烯和任选的丙烷; 其中所述正常运行阶段的特征在于小于0小时的αN（Fo / H2θO 2）的平均变化率 ^-1