公开(公告)号：WO2012060923A1

公开(公告)日：2012-05-10

申请号：PCT/US2011/049330

申请日：2011-08-26

Applicant: BATTELLE MEMORIAL INSTITUTE ,  TOTH, James, J. ,  SODERQUIST, Chuck, Z. ,  GREENWOOD, Lawrence, R. ,  MATTIGOD, Shas, V. ,  FRYXELL, Glen, E. ,  O'HARA, Matthew, J.

Inventor： TOTH, James, J. ,  SODERQUIST, Chuck, Z. ,  GREENWOOD, Lawrence, R. ,  MATTIGOD, Shas, V. ,  FRYXELL, Glen, E. ,  O'HARA, Matthew, J.

IPC: G21G1/00

CPC classification number: G21G1/0005 ,  G21G1/001 ,  G21G2001/0042

Abstract: A system and a process for producing selected isotopic daughter products from parent materials characterized by the steps of loading the parent material upon a sorbent having a functional group configured to selectively bind the parent material under designated conditions, generating the selected isotopic daughter products, and eluting said selected isotopic daughter products from the sorbent. In one embodiment, the process also includes the step of passing an eluent formed by the elution step through a second sorbent material that is configured to remove a preselected material from said eluent. In some applications a passage of the material through a third sorbent material after passage through the second sorbent material is also performed.

Abstract translation: 一种用于从母体材料生产选择的同位素子产物的系统和方法，其特征在于以下步骤：将母体材料加载到具有官能团的吸附剂上，所述吸附剂配置成在指定条件下选择性地结合母体材料，产生所选择的同位素子产物， 所述选择的来自吸附剂的同位素子产物。 在一个实施方案中，该方法还包括将通过洗脱步骤形成的洗脱液通过第二吸附剂材料的步骤，该第二吸附剂材料被配置为从所述洗脱液中除去预选物质。 在一些应用中，还进行通过第二吸附剂材料之后材料通过第三吸着剂材料的通道。

公开(公告)号：WO2021158491A1

公开(公告)日：2021-08-12

申请号：PCT/US2021/016105

申请日：2021-02-01

Applicant: BATTELLE MEMORIAL INSTITUTE

Inventor： O'HARA, Matthew, J.

IPC: C22B3/06

Abstract: Systems and methods for separating Y and Sr are provided. The systems and methods provide combinations of solutions, vessels, and/or media that can provide Y solutions of industrially beneficial concentration.

公开(公告)号：WO2020247880A1

公开(公告)日：2020-12-10

申请号：PCT/US2020/036503

申请日：2020-06-05

Applicant: BATTELLE MEMORIAL INSTITUTE

Inventor： O'HARA, Matthew, J.

IPC: B01D59/08 ,  B01D9/02 ,  G21G1/10

Abstract: Systems for separating Ra from a mixture comprising at least Ra, Pb, Bi, and Th are provided. The systems can include: a first vessel housing a first media and Th or Bi; a second vessel in fluid communication with the first vessel, the second vessel housing a second media and Pb; and a third vessel in fluid communication with the second vessel, the third vessel housing a third media and Ra, wherein at least one of the first, second, or third medias are different from the other media. Methods for separating Ra from Pb, Bi, and Th are provided, the methods can include: providing a first mixture comprising Ra, Pb, Bi, and/or Th; providing a system that can include: a first vessel housing a first media; a second vessel in fluid communication with the first vessel, the second vessel housing a second media; and a third vessel in fluid communication with the second vessel, the third vessel housing a third media; and exposing the first mixture to the first media within the first vessel then, through the fluid communication, exposing the first remainder to the second media in the second vessel, then, through fluid communication, exposing the next remainder to the third media in the third vessel, the exposing separating the Th and Bi from the Ra and Pb, and the Ra from the Pb. Methods for separating Ra from being associated with a media are also provided. The methods can include: exposing the Ra and media to a chelating agent to form a mixture comprising the Ra complexed with the chelating agent.

公开(公告)号：WO2015175758A1

公开(公告)日：2015-11-19

申请号：PCT/US2015/030734

申请日：2015-05-14

Applicant: BATTELLE MEMORIAL INSTITUTE

Inventor： VASDEKIS, Andreas, E. ,  GRATE, Jay, W. ,  O'HARA, Matthew, J.

IPC: G01N21/77 ,  G01N21/64 ,  G01N21/05 ,  G01N31/22 ,  B01L3/00 ,  B01J19/00

CPC classification number: G01N21/6428 ,  B01L3/502707 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0887 ,  B05D5/06 ,  B32B37/18 ,  B32B37/24 ,  B32B38/0012 ,  B32B2037/243 ,  G01N21/05 ,  G01N21/6408 ,  G01N21/645 ,  G01N21/77 ,  G01N2021/773 ,  G01N2021/7786 ,  Y10T156/1039

Abstract: A sensor, system, and method of making a sensor are disclosed. The sensor includes a solid polymer material (710, 760), and a dopant-containing region (750) of discrete thickness at a surface (720) of the solid polymer (710, 760). The method of creating the sensor includes impregnating the polymer material (710, 760) with the dopant by contact with a solvent solution (730) containing the dopants. A polymer/solvent gel-layer (750), whose depth increases with impregnation time, forms after contact of the polymer material (710, 760) in the solvent solution (730). The dopants are diffused into the polymer material (710, 760), forming a dopant-containing region (750) of discrete thickness at a surface (720) of the solid polymer (710, 760). A microfluid structure with microchannels is formed by imprinting grooves or channels in the polymer/solvent gel-layer or dopant-containing region (750), for example by using a stamp (740), and bonding the imprinted layer to a top plate (780).

Abstract translation: 公开了传感器，系统和制造传感器的方法。 该传感器包括固体聚合物材料（710,760）和在固体聚合物（710,760）的表面（720）处具有离散厚度的含掺杂剂区域（750）。 创建传感器的方法包括通过与含有掺杂剂的溶剂溶液（730）接触来掺杂掺杂剂的聚合物材料（710,760）。 在聚合物材料（710,760）在溶剂溶液（730）中接触之后形成其浸渍时间深度增加的聚合物/溶剂凝胶层（750）。 掺杂剂扩散到聚合物材料（710,760）中，在固体聚合物（710,760）的表面（720）处形成离散厚度的掺杂剂区域（750）。 具有微通道的微流体结构通过在聚合物/溶剂凝胶层或掺杂剂区域（750）中压印凹槽或沟道而形成，例如通过使用印模（740），并将印刷层结合到顶板（780 ）。

公开(公告)号：WO2008130881A1

公开(公告)日：2008-10-30

申请号：PCT/US2008/060181

申请日：2008-04-14

Applicant: BATTELLE MEMORIAL INSTITUTE ,  O'HARA, Matthew, J. ,  RAPKO, Brian, M. ,  EDWARDS, Matthew, K. ,  WESTER, Dennis, W.

Inventor： O'HARA, Matthew, J. ,  RAPKO, Brian, M. ,  EDWARDS, Matthew, K. ,  WESTER, Dennis, W.

IPC: G21G1/04 ,  B01D15/18

CPC classification number: G21G4/08 ,  B01J20/0259 ,  B01J20/10 ,  B01J20/18 ,  B01J20/22 ,  B01J20/262 ,  B01J20/265 ,  B01J20/268 ,  B01J20/28042 ,  B01J20/3204 ,  B01J20/3206 ,  B01J20/3208 ,  B01J2220/46

Abstract: Medical isotope generator systems are disclosed according to some aspects. In one aspect, a 90 Y generator system comprises a generator column (202), a concentration column (203), and a flow control system, through which the generator column and the concentration column are in fluid communication. The flow control system provides a plurality of flow configurations for delivering a milking solution to the generator column, the concentration column, or both, and for delivering an eluent solution to the concentration column in either a forward or a reverse flow direction. The generator column can comprise a 90 Sr stock adsorbed on a sorbent. The milking solution preferentially elutes 90 Y from the generator column. The concentration column comprises a sorbent that captures 90 Y from the milking solution without altering the milking solution. The eluent solution elutes 90 Y from the concentration column.

Abstract translation: 根据一些方面公开了医用同位素发生器系统。 在一个方面，发电机系统包括发电机塔（202），浓缩塔（203）和流量控制系统，发电机塔和浓缩塔通过该系统流体连通 。 流量控制系统提供多个流动配置，用于将挤奶溶液输送到发生器塔，浓缩塔或两者，并用于在前向或反向流动方向上将洗脱液输送到浓缩塔。 生成塔可以包含吸附剂上吸附的超临界流体原料。 挤奶溶液优先从发生器柱洗脱90％。 浓缩柱包括从挤奶溶液捕获<！ - SIPO - >而不改变挤奶溶液的吸附剂。 洗脱溶液从浓缩柱洗脱出90℃。