公开(公告)号：WO2016092333A2

公开(公告)日：2016-06-16

申请号：PCT/GB2015053975

申请日：2015-12-14

Applicant: BIO AMD HOLDINGS LTD

Inventor： DJENNATI NASR-EDDINE ,  MITCHELL ANDREW ,  BANKS DOMINIC

IPC: B01L3/00 ,  B01F13/00

CPC classification number: B01L3/502723 ,  B01F13/0059 ,  B01F13/0818 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2300/0825 ,  B01L2300/087 ,  B01L2400/0406 ,  B01L2400/0633 ,  B01L2400/0683 ,  B01L2400/0694 ,  G01N33/4905

Abstract: An assay apparatus for determining properties of a sample, such as coagulation properties of blood comprises first and second chambers for receiving the sample. The chambers are arranged so that the sample can move downstream from the first chamber to the second chamber in series. The apparatus is provided with an openable valve or vent arranged such that opening the valve or vent allows flow from the first chamber to the second chamber. The openable vent can be located in, or downstream of the second chamber and can be opened by moving a closure to reveal holes, or by puncturing a layer to open the passage. The valve may be formed of a frustoconical seat and a spherical body.

Abstract translation: 用于确定样品的性质（例如血液的凝固性质）的测定装置包括用于接收样品的第一和第二室。 这些室被布置成使得样品可以从第一室的下游串联移动到第二室。 该设备设置有可打开的阀或通风口，其布置成使得打开阀或排气口允许从第一室流到第二室。 可打开的通气口可以位于第二室的第二室中或下游，并且可以通过移动封闭件以露出孔来打开，或者通过穿刺层来打开通道。 阀可以由截头圆锥形座和球体形成。

公开(公告)号：WO2015087092A3

公开(公告)日：2015-09-11

申请号：PCT/GB2014053703

申请日：2014-12-15

Applicant: BIO AMD HOLDINGS LTD

Inventor： DJENNATI NASR-EDDINE ,  MITCHELL ANDREW

IPC: B01L3/00 ,  F16K99/00

CPC classification number: B01L3/502738 ,  A61M39/22 ,  B01L2400/0633 ,  F16K99/0011 ,  F16K99/0046 ,  F16K2099/0086

Abstract: An assay apparatus for determining properties of a sample. The apparatus has first and second chambers for receiving a sample. The first and second chambers are linked by a conduit along which at least part of the sample may travel so that the sample can move from the first chamber to the second chamber in series. The apparatus also has a slot extending from the conduit and a valve body comprising magnetic or magnetically susceptible material which is housed at least substantially within the slot. The valve body is movable between a first position in which the valve body is arranged at least substantially outside the conduit and a second position in which the valve body extends across the conduit thereby restricting a sample from travelling along the conduit from the first chamber to the second chamber. The valve body is slidably movable between the two positions by an external magnetic field.

Abstract translation: 一种测定样品性质的测定装置。 该设备具有用于接收样品的第一和第二室。 第一腔室和第二腔室由导管连接，至少部分样品可以沿着导管行进，使得样品可以从第一腔室串联移动到第二腔室。 该设备还具有从导管延伸的槽和包括磁性或磁性敏感材料的阀体，该阀体至少基本上容纳在槽内。 所述阀体可在第一位置和第二位置之间移动，在所述第一位置中，所述阀体至少基本上布置在所述导管的外部，在所述第二位置，所述阀体横跨所述导管延伸，从而限制样品沿着所述导管从所述第一腔室行进到所述第一腔室 第二室。 阀体通过外部磁场在两个位置之间可滑动地移动。