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公开(公告)号：WO2022258841A1
公开(公告)日：2022-12-15
申请号：PCT/EP2022/065915
申请日：2022-06-10
Applicant: BIOARCTIC AB
Inventor： FALK, Ronny , FRESKGÅRD, Per-Ola , HONEK, Ken , SANDERSJÖÖ, Lisa
Abstract: A bispecific binding molecule is provided, which comprises two identical antibody heavy chains and a single chain component which is a polypeptide chain comprising two identical antibody light chains linked to a single chain binding module with affinity for a target which mediates transport of the bispecific binding molecule across the blood-brain barrier (BBB). Also provided are therapeutic, prophylactic, prognostic and diagnostic uses of the bispecific binding molecule.
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