公开(公告)号：WO2019143629A1

公开(公告)日：2019-07-25

申请号：PCT/US2019/013685

申请日：2019-01-15

申请人： CARDIAC PACEMAKERS, INC.

发明人： DELANEY, JR, Joseph T. ,  RO, Andrew J. ,  WULFMAN, David R. ,  GURUNG, Niraj ,  WILLOUGHBY, Patrick

IPC分类号： A61L27/18 ,  C08G18/48 ,  C08G18/62 ,  C08G18/76 ,  C08G18/12 ,  C08G18/40 ,  C08G18/28

CPC分类号： C08G18/6208 ,  A61L27/16 ,  A61L29/041 ,  A61L31/048 ,  A61L31/129 ,  A61L31/143 ,  C08G18/12 ,  C08G18/2865 ,  C08G18/4063 ,  C08G18/4808 ,  C08G18/4854 ,  C08G18/6204 ,  C08G18/7671 ,  C08G18/833 ,  C08G18/3206 ,  C08L53/00

摘要： A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.

公开(公告)号：WO2018165273A1

公开(公告)日：2018-09-13

申请号：PCT/US2018/021311

申请日：2018-03-07

申请人： CARDIAC PACEMAKERS, INC.

发明人： DELANEY, Joseph T. Jr. ,  RO, Andrew J. ,  WILLOUGHBY, Patrick ,  GURUNG, Niraj

IPC分类号： C08F110/10 ,  C08F8/02 ,  C08F8/06

摘要： A method for making a polyisobutylene diol from a polyisobutylene diallyl. The method includes hydroborating the polyisobutylene diallyl to produce a polyisobutylene dialkyl borane, and oxidizing the polyisobutylene dialkyl borane to form the polyisobutylene diol. The polyisobutylene diallyl is hydroborated by combining in situ the polyisobutylene diallyl with a borane-coordinating solvent, an alkaline metal salt of borohydride, and an acid. The alkaline metal salt of borohydride is combined with the polyisobutylene diallyl before the acid is combined with the polyisobutylene diallyl.